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Advantages of Epizomal Vector Gene Therapy for Sarcopenia
Epizomal vector gene therapy is non-integrating and does not pose risks to the genome like viruses. It does not require immunosuppressants and can be removed with tetracycline if needed. The therapy lasts one and a half to two years and can be repeated, unlike viral vectors. The therapy is being targeted for conditions like sarcopenia, the loss of muscle mass in older adults, which is a significant factor in aging and mortality. The therapy aims to increase levels of a naturally occurring peptide called fallestin to preserve muscle mass and promote anti-aging effects.