The personal list of top problems to work on is crucial for one's career as it accounts for individual values, judgments, and opportunities. Personal fit and motivation play a significant role in determining where one can have the most impact. It is essential to find work aligned with personal motivation to maximize impact. There are numerous opportunities to make a difference in areas that one might find enjoyable, even if they are not initially considered. Developing new passions is easier than anticipated, allowing for the pursuit of meaningful work that aligns with personal interests and strengths.