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Ep 180 Acetaminophen Poisoning – Pitfalls in Assessment and Management

Emergency Medicine Cases

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Acetaminophen toxicity: what to do when you see a rise in ALT levels

Toxicologists prefer using AST as it rises first and falls faster than ALT, providing a better indication of patient recovery. Some acetaminophen tablets are slow release, with the second dose being released in the small bowel. This may lead to line-crossers and requires repeat testing in 8-12 hours for an accurate result.

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