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#256 ‒ The endocrine system: exploring thyroid, adrenal, and sex hormones | Peter Attia, M.D.

The Peter Attia Drive

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Understanding Testosterone Replacement Therapy and Free Testosterone

Testosterone replacement therapy is more complicated than people think. The biologically active free testosterone only represents 1-3% of total testosterone, but it's all you need. Calculating free T is difficult, but online calculators can help. DHT is more potent than testosterone and affects transcription inside the nucleus of a cell.

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