Ahmed Alkarkhi
@IbnAlHaytham
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CRISPR | The Future of Genetic Engineering

Dr. Matt and Dr. Mike's Medical Podcast

Recessive and Dominant Inheritance of Diseases and Disorders

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Some diseases and disorders can be inherited in a recessive manner, while others are inherited dominantly. In recessive inheritance, there is a backup gene that compensates for any dysfunction caused by a mutation in one gene. However, in dominantly inherited disorders, a mutation in one gene can lead to a toxic gain of function, where the protein produced by the gene is changed in a way that is detrimental to the organism. This overrides any functionality provided by the other gene. Recessive mutations usually result in a loss of function, while dominant mutations result in a gain of function that is harmful to the organism.

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