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Metabolic Mind cover image

Metformin, Insulin Resistance and Bipolar depression: From research to clinical care

Metabolic Mind

NOTE

High Rates of Insulin Resistance in Patients with Bipolar Disorder

Patients with bipolar disorder exhibit alarming rates of metabolic dysregulation, with 54% demonstrating either type 2 diabetes or insulin resistance, a prevalence three times higher than that observed in the general population. Furthermore, a significant diagnostic gap exists, as 40% of those with type 2 diabetes in the examined cohort were undiagnosed, indicating that the metabolic dysregulation associated with bipolar disorder is frequently overlooked and under-tested.

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