Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast cover image

Episode 46: Obstetric Pharmacology and Fetal Assessment with Mike Hofkamp

Anesthesia and Critical Care Reviews and Commentary (ACCRAC) Podcast

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Can Propofol Cross Placenta?

propofol obviously is lipophilic it can cross the placenta. Apgar scores are higher in thiopental inductions compared to propofol inductions. The effects of propofol are going to be short-lived and not realized unless the fetus is delivered with the propofol in its bloodstream. With medazlam that is a theoretical risk of tragedy and acidity so we do avoid medazlam in the first and second trimesters.

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