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Exquisite Failures: The 233rd Evolutionary Lens with Bret Weinstein and Heather Heying

DarkHorse Podcast

NOTE

Efficiency of Endogenously Generated Fever

Endogenously generated fever is more useful than behavioral fever because maintaining body temperature is energetically expensive, with 85% of calories used for this purpose. The predictability of body temperature due to endothermy allows enzymes to be more efficient and specialized, enhancing biochemical processes. In contrast, a fever can disrupt these processes by altering the expected temperature, impacting enzyme efficiency. Ectothermic organisms with fluctuating body temperatures must have generalist physiology to adapt to environmental heat variations.

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