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Joel Greene Podcast Part 1: How To Reboot The Gut, Eat Cheesecake Without Gaining Weight, Amplify Any Fasting Protocol & Maximize Fat Loss.

Ben Greenfield Life

NOTE

Butyrate Production and TNF-Alpha Impairment in Gut Inflammation

The impairment of butyrate production and transport in inflamed mucosa is linked to the presence of TNF-alpha, necessitating its clearance before fiber can effectively work. The shared receptor GDP-109, which is expressed in the gut and adipose tissue, plays a role in this process. Niacin application into the impaired butyrate transporter in inflamed mucosa seems to contribute to restoring mucosal lining function. Further steps to clear TNF-alpha can aid in addressing gut issues effectively.

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