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#99 – Karl Friston: Neuroscience and the Free Energy Principle

Lex Fridman Podcast

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Metabolism and Blood Flow in the Brain

The brain's gray matter forms a surface on a large network of structured connections. Neural activity in a small area of the brain requires rapid and specific blood flow to meet its energy demands. This need for immediate and precise blood supply means that brain metabolism must be driven in the moment, requiring quick response within a few seconds. This rapid metabolism and blood flow patterns can be detected through imaging techniques.

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