Ijeoma Uchegbu on using nanoparticles to transform medicines
The Life Scientific
Innovating Drug Delivery: The Evolution of Stable Nanoparticles
Developing stable nanoparticles for drug delivery involves using larger polysaccharide molecules instead of smaller fatty molecules. The longer fibers of polysaccharides create a more entangled structure, which helps retain the drug within the nanoparticles, preventing leakage during transport. This innovative approach leads to the creation of nanoparticles with increased stability. Moreover, focusing on the molecular characteristics that contribute to this stability is crucial, alongside ensuring that nanoparticles possess adhesive properties. This stickiness enhances their residence time at cell surfaces, thereby improving drug uptake into cells.
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