PsychEd: Educational Psychiatry Podcast

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners.   This episode covers the psychiatric aspects of chronic pain with expert guest:   Dr. Leon Tourian, Associate Professor in the Department of Psychiatry at McGill University, and psychiatrist at the MUHC Alan Edwards Pain Management Unit.   The learning objectives for this episode are as follows: By the end of this episode, you should be able to Explore the role of psychiatry in the management of pain Discuss the epidemiology of psychiatric comorbidities in pain disorders. Outline the pathophysiology of pain and its relationship to psychiatric disorders. Outline the role of non-pharmacological management/treatment of pain including psychotherapy and central neuromodulation Discuss a general psychopharmacology approach in the management of pain relief and psychiatric comorbidities with chronic pain (including SNRI, TCAs, anticonvulsants, antipsychotics and cannabinoids). Discuss the intersection of pain medicine with somatic symptom and related disorders   Guest: Dr. Leon Tourian Hosts: Dr. Sarah Hanafi (PGY3), Dr. Nima Nahiddi (PGY3), Audrey Le (CC4) Audio editing by Audrey Le Show notes by Dr. Nima Nahiddi Episode Infographic by Dr. Luba Bryushkova     Interview Content: Introduction and learning objectives – 0:00 Role of psychiatry in management of chronic pain – 1:45 Psychiatric co-morbidities in patients with chronic pain – 5:45 Biological link between pain and psychiatric co-morbidities – 11:00 Psychological approach to understanding and management of chronic pain– 14:30 Central neuromodulation strategies for chronic pain – 21:00 General pharmacological approach to the management of chronic pain – 22:30 Pathogenesis of neuropathic and somatic visceral pain – 30:00 Antipsychotics in the management of chronic pain – 37:00 Cannabis in the management of chronic pain – 40:30 Somatic symptom disorder – 46:00 Stigma in chronic pain disorders – 53:10 Treatment of somatic symptom disorder – 58:30 Psychiatry and the stigma of chronic pain disorders– 61:00 Closing remarks – 65:15   Articles and Resources: Guideline for opioid therapy and chronic noncancer pain (CMAJ) Guideline The 2017 Canadian Guideline for Opioids for Chronic Non-Cancer Pain (McMaster University) List of Pain & Opioid Initiatives (2017) (CFPC) Canadian Pain Task Force Report: June 2019   References: Dersh, J., Polatin, P. B., & Gatchel, R. J. (2002). Chronic pain and psychopathology: research findings and theoretical considerations. Psychosomatic medicine, 64(5), 773–786. https://doi.org/10.1097/01.psy.0000024232.11538.54   Katz, J., Rosenbloom, B. N., & Fashler, S. (2015). Chronic Pain, Psychopathology, and DSM-5 Somatic Symptom Disorder. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 60(4), 160–167. https://doi.org/10.1177/070674371506000402   O'Connell, N. E., Marston, L., Spencer, S., DeSouza, L. H., & Wand, B. M. (2018). Non-invasive brain stimulation techniques for chronic pain. The Cochrane database of systematic reviews, 4(4), CD008208. https://doi.org/10.1002/14651858.CD008208.pub5   Ratcliffe, G. E., Enns, M. W., Belik, S. L., & Sareen, J. (2008). Chronic pain conditions and suicidal ideation and suicide attempts: an epidemiologic perspective. The Clinical journal of pain, 24(3), 204–210. https://doi.org/10.1097/AJP.0b013e31815ca2a3   Tunks, E. R., Crook, J., & Weir, R. (2008). Epidemiology of chronic pain with psychological comorbidity: prevalence, risk, course, and prognosis. Canadian journal of psychiatry. Revue canadienne de psychiatrie, 53(4), 224–234. https://doi.org/10.1177/070674370805300403   CPA Note: The views expressed in this podcast do not necessarily reflect those of the Canadian Psychiatric Association. For more PsychEd, follow us on Twitter (@psychedpodcast), Facebook (PsychEd Podcast), and Instagram (@psyched.podcast). You can provide feedback by email at psychedpodcast@gmail.com. For more information, visit our website at psychedpodcast.org.

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This episode covers ketamine for treatment-resistant depression (TRD) with Dr. Sandhya Prashad, a psychiatrist and the founder and medical director of Houston Ketamine Therapeutics. She has extensive expertise using ketamine and is one of the most experienced ketamine psychiatrists in the United States, with her clinical practice focusing on TRD and incorporating transcranial magnetic stimulation (TMS), sometimes in conjunction with ketamine. Dr. Prashad is also a founding member and current president of the American Society of Ketamine Physicians (ASKP), a non-profit organization created to advocate for the safe use of ketamine for mental illness and pain disorders and to expand access to ketamine therapy.   We’re also experimenting with something new for this episode — providing a transcript of the entire interview! The transcript can be found at psychedpodcast.org/transcripts/ketamine. We’d love to hear your feedback as listeners on this as a feature, including whether it’s something you’d be interested in seeing for other episodes moving forward!   The learning objectives for this episode are as follows:   By the end of this episode, you should be able to… Describe ketamine and how it came to be used in the field of psychiatry. Develop an appreciation for benefits and potential harms associated with ketamine and how this compares to other treatments for depression. Understand how ketamine fits into the treatment of depression and suicidality, patient characteristics to consider before initiation, potential mechanisms of action, different models of administration, and incorporation of psychotherapy.   Guest expert: Dr. Sandhya Prashad   Hosts: Jimmy Qian (MS2), Dr. Nikhita Singhal (PGY2), Dr. Chase Thompson (PGY3)   Audio editing by: Dr. Chase Thompson   Show notes by: Gray Meckling (MS4)   Interview transcript by: Gray Meckling   00:00 – Introduction 03:00 – Learning objectives 03:30 – History of ketamine 06:20 – Recreational use of ketamine, phenomenology of the ketamine experience 09:45 – Where does ketamine fall in the algorithm for treatment of depression? 11:50 – Ketamine’s use in acute suicidality 13:40 – Ketamine contraindications 14:40 – Ketamine efficacy 19:00 – Combining ketamine with rTMS 21:15 – Limitations to ketamine 24:35 – Ketamine mechanism of action 26:05 – Ketamine formulations, and integrating ketamine into psychotherapy 33:10 – Combining ketamine with traditional antidepressant treatment 37:30 – Practicalities of administering ketamine 39:40 – Ketamine as treatment for OCD and PTSD 41:40 – Closing remarks   Resources: American Society of Ketamine Physicians, Psychotherapists & Practitioners (ASKP) Sandhya Prashad, MD (Website) NEJM interview with Dr. Roy Perlis: Esketamine for Treatment-Resistant Depression — First FDA-Approved Antidepressant in a New Class   References: Berman, R., Cappiello, A., Anand, A., Oren, D., Heninger, G., Charney, D.. (2000) Antidepressant effects of ketamine in depressed patients. Biol Psychiatry 47: 351–354. Daly, E. J., Trivedi, M. H., Janik, A., Li, H., Zhang, Y., Li, X., ... & Thase, M. E. (2019). Efficacy of esketamine nasal spray plus oral antidepressant treatment for relapse prevention in patients with treatment-resistant depression: a randomized clinical trial. JAMA psychiatry, 76(9), 893-903. J.W. Murrough, D.V. Iosifescu, L.C. Chang, et al. Antidepressant efficacy of ketamine in treatment-resistant major depression: a two site randomized controlled trial. Am. J. Psychiatry, 2013 (170) (2013), pp. 1134-1142 Kim, J., Farchione, T., Potter, A., Chen, Q., & Temple, R. (2019). Esketamine for treatment-resistant depression-first FDA-approved antidepressant in a new class. N Engl J Med, 381(1), 1-4. McIntyre, R. S., Rosenblat, J. D., Nemeroff, C. B., Sanacora, G., Murrough, J. W., Berk, M., ... & Stahl, S. (2021). Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation. American Journal of Psychiatry, appi-ajp. Muetzelfeldt L, Kamboj SK, Rees H, Taylor J, Morgan CJA, Curran HV. Journey through the K-hole: Phenomenological aspects of ketamine use. Drug and Alcohol Dependence [Internet]. 2008 Jun 1;95(3):219–29. Sanacora G, Frye MA, McDonald W, Mathew SJ, Turner MS, Schatzberg AF, Summergrad P, Nemeroff CB. A consensus statement on the use of ketamine in the treatment of mood disorders. JAMA psychiatry. 2017 Apr 1;74(4):399-405. Williams NR, Heifets BD, Blasey C, Sudheimer K, Pannu J, Pankow H, Hawkins J, Birnbaum J, Lyons DM, Rodriguez CI, Schatzberg AF. Attenuation of antidepressant effects of ketamine by opioid receptor antagonism. American Journal of Psychiatry. 2018 Dec 1;175(12):1205-15. Williams NR, Heifets BD, Bentzley BS, Blasey C, Sudheimer KD, Hawkins J, Lyons DM, Schatzberg AF. Attenuation of antidepressant and anti suicidal effects of ketamine by opioid receptor antagonism. Molecular psychiatry. 2019 Dec;24(12):1779-86. Zarate, C., Singh, J., Carlson, P., Brutsche, N., Ameli, R., Luckenbaugh, D.. (2006a) A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. Arch Gen Psychiatry 63: 856–864.   CPA Note: The views expressed in this podcast do not necessarily reflect those of the Canadian Psychiatric Association (CPA). For more PsychEd, follow us on Twitter (@psychedpodcast), Facebook (PsychEd Podcast), and Instagram (@psyched.podcast). You can provide feedback by email at psychedpodcast@gmail.com. For more information, visit our website at psychedpodcast.org.

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This episode covers the treatment of borderline personality disorder with expert guests: Dr. Robert Biskin, Associate Professor in the Department of Psychiatry at McGill University, and inpatient psychiatrist at the Borderline Personality Disorder Clinic at the McGill University Health Centre, as well as the inpatient psychiatrist at the Jewish General Hospital. Dr. Ronald Fraser, Associate Professor in the Department of Psychiatry at McGill University, Adjunct Professor at Dalhousie University, and head of the Inpatient Detoxification Services and Addictions Unit, as well as director of the Extended Care Borderline Personality Disorder Clinic at the McGill University Health Centre. The learning objectives for this episode are as follows:  By the end of this episode, you should be able to… Understand the frame and principles of care for the treatment of individuals with borderline personality disorder. Explore the approach to the treatment of individuals with borderline personality disorder: On presentation in crisis to the emergency department. During an inpatient psychiatric admission. In the context of psychiatric outpatient care. Understand the use of psychotherapy in the treatment of individuals with borderline personality disorder. Understand the use of pharmacotherapy in the treatment of individuals with borderline personality disorder Guest: Dr. Robert Biskin and Dr. Ronald Fraser Hosts: Dr. Sarah Hanafi (PGY3), Dr. Nima Nahiddi (PGY3), Audrey Le (CC4) Audio editing by Audrey Le Show notes by Dr. Nima Nahiddi Interview Content:  Introduction – 0:00 Learning objectives – 0:35 Principles of care for treatment of BPD – 1:16 The therapeutic frame – 5:40  Approach to the management of emergency department presentations – 9:10 Dialectical behaviour therapy (DBT) – 16:15 Suicidality and self-harm in BPD diagnosis – 21:05 Pharmacotherapy for symptom treatment – 22:40 Treatment of co-morbid disorders – 32:35  Management of safety risk – 39:30 Stigma in treatment of BPD – 46:05 Closing remarks – 52:00 Resources/Articles: The Treatment of Borderline Personality Disorder: Implications of Research on Diagnosis, Etiology, and Outcome | Annual Review of Clinical Psychology (annualreviews.org) Efficacy of Psychotherapies for Borderline Personality Disorder: A Systematic Review and Meta-analysis | Psychiatry | JAMA Psychiatry | JAMA Network National Education Alliance for Borderline Personality Disorder References:   Cristea I.A., Gentili C, Cotet CD, Palomba D, Barbui C, Cuijpers P. (2017) Efficacy of Psychotherapies for Borderline Personality Disorder: A Systematic Review and Meta-analysis. JAMA Psychiatry. 74(4):319–328. doi:10.1001/jamapsychiatry.2016.4287 Ingenhoven T, Lafay P, Rinne T, Passchier J, Duivenvoorden H  J. (2010) Effectiveness of pharmacotherapy for severe personality disorders: meta-analyses of randomized controlled trials. Clin Psychiatry. 71(1):14.  Paris J. (2009). The Treatment of Borderline Personality Disorder: Implications of Research on Diagnosis, Etiology, and Outcome. Review of Clinical Psychology. 5:1, 277-290 Stoffers J, Vollm BA, Rucker G, Timmer A, Huband N. (2010) Pharmacological interventions for borderline personality disorder. Cochrane Database of Systematic Reviews, Issue 6. Art. No.: CD005653. DOI: 10.1002/14651858.CD005653 Storebø  OJ, Stoffers-Winterling  JM, Völlm  BA, Kongerslev  MT, Mattivi  JT, Jørgensen  MS, Faltinsen  E, Todorovac  A, Sales  CP, Callesen  HE, Lieb  K, Simonsen  E.  (2020) Psychological therapies for people with borderline personality disorder. Cochrane Database of Systematic Reviews, Issue 5. Art. No.: CD012955. DOI: 10.1002/14651858.CD012955.pub2     CPA Note: The views expressed in this podcast do not necessarily reflect those of the Canadian Psychiatric Association. For more PsychEd, follow us on Twitter (@psychedpodcast), Facebook (PsychEd Podcast), and Instagram (@psyched.podcast). You can provide feedback by email at psychedpodcast@gmail.com. For more information, visit our website at psychedpodcast.org.  

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This episode covers the diagnosis of borderline personality disorder with expert guests: Dr. Robert Biskin, Associate Professor in the Department of Psychiatry at McGill University, psychiatrist at the Borderline Personality Disorder Clinic at the McGill University Health Centre, as well as inpatient psychiatrist at the Jewish General Hospital. Dr. Ronald Fraser, Associate Professor in the Department of Psychiatry at McGill University, Adjunct Professor at Dalhousie University, head of the Inpatient Detoxification Services and Addictions Unit, as well as director of the Extended Care Borderline Personality Disorder Clinic at the McGill University Health Centre.   By the end of this episode, you should be able to… List the DSM-5 diagnostic criteria of borderline personality disorder. Recall the epidemiology of borderline personality disorder. Consider the risk factors and posited causal mechanisms for borderline personality disorder, including developmental and neurobiological mechanisms.  Discuss the clinical presentation of borderline personality in different clinical settings, including the Emergency and Outpatient settings.  Recognize the differential diagnoses for patients presenting with borderline personality disorder. List the common comorbid psychiatric and general medical conditions with borderline personality disorder. Discuss the common diagnostic challenges and pitfalls. Explore the stigma surrounding the diagnosis of borderline personality disorder, and discuss a therapeutic approach to providing psychoeducation to patients with this diagnosis.    Guests: Dr. Robert Biskin and Dr. Ronald Fraser. Hosts: Dr. Sarah Hanafi (PGY3), Dr. Nima Nahiddi (PGY3), Audrey Le (CC4). Audio editing by Audrey Le. Show notes by Dr. Nima Nahiddi.   Interview Content: Introduction – 0:00 Learning objectives – 2:03 DSM-5 definition of personality disorder, and borderline personality disorder (BPD) – 3:00 Other associated features of BPD – 4:36 Distinguishing BPD from other psychiatric and co-morbid conditions – 5:55 Epidemiology of BPD – 13:48 BPD over the lifecycle – 18:05 Explanatory models for the development of BPD – 21:20 Differences in the presentation of BPD – 26:00 Approach to a BPD diagnosis in the emergency department – 31:05 Stigma surrounding BPD diagnosis and disclosure of diagnosis – 33:51 Clinical pearls for screening of BPD – 41:11 Evidenced based screening tools or scales for BPD diagnosis – 46:22 Closing – 48:40 Resources: MSI-BDP: MacLean Screening Index for BPD Diagnostic Interview for BPD – Revised (DIB-R): https://psycnet.apa.org/record/1990-11356-001 Articles: Diagnosing borderline personality disorder | CMAJ   References: Biskin, R.S., Paris, J. (2012). Diagnosing borderline personality disorder. CMAJ. 184 (16), 1789-1794. Zanarini, M. C., Gunderson, J. G., Frankenburg, F. R., & Chauncey, D. L. (1989). The revised Diagnostic Interview for Borderlines: Discriminating BPD from other Axis II disorders. Journal of Personality Disorders, 3(1), 10–18. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). https://doi.org/10.1176/appi.books.9780890425596   CPA Note: The views expressed in this podcast do not necessarily reflect those of the Canadian Psychiatric Association. For more PsychEd, follow us on Twitter (@psychedpodcast), Facebook (PsychEd Podcast), and Instagram (@psyched.podcast). You can provide feedback by email at psychedpodcast@gmail.com. For more information, visit our website at psychedpodcast.org.

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This episode covers psychodynamic psychotherapy with Dr. Rex Kay. Dr. Kay is a staff psychiatrist at Mount Sinai Hospital, assistant professor and modality lead for dynamic psychotherapy at the University of Toronto, as well as a faculty member at the Toronto Institute for Contemporary Psychoanalysis.    The learning objectives for this episode are as follows:   By the end of this episode, you should be able to… Define psychodynamic psychotherapy.  Describe the core concepts of psychodynamic therapy.  Determine who may be an appropriate patient for psychodynamic psychotherapy.  Describe the evidence base for psychodynamic psychotherapy.  Compare and contrast psychodynamic therapy to other psychotherapies.    Guest: Dr. Rex Kay   Produced and Hosted by: Jordan Bawks and Anita Corsini   Audio editing by: Anita Corsini   Resources: Ars Medica: A Journal of Medicine, the Arts, and Humanities Canadian Institute for Child and Adolescent Psychoanalytic Psychotherapy  Narrative Competence Psychotherapy Group at Mount Sinai Hospital Toronto Institute for Contemporary Psychoanalysis Toronto Institute of Psychoanalysis    References: Black, M. & Mitchell, S. (2016). Freud and beyond: A history of modern psychoanalytic thought. Basic Books.  Cabaniss, D. L., Cherry, S., Douglas, C. J., & Schwartz, A. R. (2017). Psychodynamic psychotherapy: A clinical manual. Wiley.   Driessen, E., Hegelmaier, L. M., Abbass, A. A., Barber, J. P., Dekker, J. J., Van, H. L., Jansma, E. P., & Cuijpers, P. (2015). The efficacy of short-term psychodynamic psychotherapy for depression: A meta-analysis update. Clinical Psychology Review, 42, 1-15. doi: 10.1016/j.cpr.2015.07.004 Eppel, A. (2018). Short-term psychodynamic psychotherapy. Springer.  Karen, R. (1994). Becoming attached: First relationships and how they shape our capacity to love. Oxford.  Safran, J. D. (2012). Psychoanalysis and Psychoanalytic Therapies. American Psychological Association.  Summers, R. F. & Barber, J. P. (2010). Psychodynamic Therapy: A Guide to Evidence-Based Practice. Guilford. CPA Note: The views expressed in this podcast do not necessarily reflect those of the Canadian Psychiatric Association. For more PsychEd, follow us on Twitter (@psychedpodcast), Facebook (PsychEd Podcast), and Instagram (@psyched.podcast). You can provide feedback by email at psychedpodcast@gmail.com. For more information, visit our website at psychedpodcast.org.

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This episode covers anti-black racism and mental health with Dr. Kwame McKenzie. Dr. McKenzie is an international expert on the social causes of illness, suicide and the development of effective, equitable health systems. He is a Professor of Psychiatry at University of Toronto and a staff psychiatrist and Director of Health Equity at the Centre of Addiction and Mental Health.   The learning objectives:   By the end of this episode, you should be able to… Understand the history and legacy of racism and mental health in the black community Understand the current state of racism towards black people and the impacts on their mental health. Explore how healthcare workers can be anti-racist in providing mental health care and how the system can change to improve the mental health of black people.   Host(s): Anita Corsini (social worker), Dr. Alex Raben (staff psychiatrist), and Rebecca Marsh (CC4)   Produced by: Anita Corsini, Rebecca Marsh, Randi Wang (CC4), and Dr. Alex Raben   Guest experts: Dr. Kwame McKenzie, staff psychiatrist   Resources:   Manual for Cognitive-Behavioural Therapy for English-Speaking People of Caribbean Origin The City of Toronto has curated a list of Mental Health Resources for Black Communities. Organizations include: Across Boundaries Black Creek Community Health Centre Caribbean African Canadian Social Services Rexdale Community Health Centre TAIBU Community Health Centre The Black Health Alliance Women’s Health in Women’s Hands Community Health Centre   References:   Adelman, J. (2003). Study in Blue and Grey, Police Interventions with People with Mental Illness: A Review of Challenges and Responses [Ebook]. Canadian Mental Health Association. Retrieved 7 October 2020, from https://cmha.bc.ca/wp-content/uploads/2016/07/policereport.pdf. Bailey, R. K., Mokonogho, J., & Kumar, A. (2019). Racial and ethnic differences in depression: current perspectives. Neuropsychiatric disease and treatment, 15, 603–609. https://doi.org/10.2147/NDT.S128584 Bor, J., Venkataramani, A., Williams, D., & Tsai, A. (2018). Police killings and their spillover effects on the mental health of black Americans: a population-based, quasi-experimental study. The Lancet, 392(10144), 302-310. https://doi.org/10.1016/s0140-6736(18)31130-9 Bresnahan, M., Begg, M., Brown, A., Schaefer, C., Sohler, N., & Insel, B. et al. (2007). Race and risk of schizophrenia in a US birth cohort: another example of health disparity?. International Journal Of Epidemiology, 36(4), 751-758. https://doi.org/10.1093/ije/dym041 Chakraborty, A., McKenzie, K., & King, M. (2009). Discrimination, ethnicity and psychosis — a qualitative study. Ethnicity And Inequalities In Health And Social Care, 2(1), 18-29. https://doi.org/10.1108/17570980200900004 Fernando, S. (2014). Racism in psychiatry. In R. Moodley & M. Ocampo (Eds.), Critical Psychiatry and Mental Health: Exploring the Work of Suman Fernando in Clinical Practice (pp. 22-32). Taylor & Francis.   Kirkmayer, L. J. (2014). Critical psychiatry in Canada. In R. Moodley & M. Ocampo (Eds.), Critical Psychiatry and Mental Health: Exploring the Work of Suman Fernando in Clinical Practice (pp. 170-181). Taylor & Francis.   Kuper, A. (2018). Cultural Safety & Equity [Lecture PDF]. Retrieved from University of Toronto Faculty of Medicine.  Maynard, R. (2017). Policing Black Lives: State Violence in Canada from Slavery to the Present. Fernwood. McKenzie, K. (2002). Does racial discrimination cause mental illness?. European Psychiatry, 17, 84. https://doi.org/10.1016/s0924-9338(02)80385-6 McKenzie, K., & Bhui, K. (2007). Institutional racism in mental health care. BMJ, 334(7595), 649-650. https://doi.org/10.1136/bmj.39163.395972.80 MCRRT - St. Joseph's Healthcare Hamilton. St. Joseph's Healthcare Hamilton. (2020). Retrieved 7 October 2020, from https://www.stjoes.ca/health-services/mental-health-addiction-services/mental-health-services/coast/mcrrt. Richardson, L. (2019). Diversity and Advocacy [Lecture PDF]. Retrieved from University of Toronto Faculty of Medicine.  CPA Note: The views expressed in this podcast do not necessarily reflect those of the Canadian Psychiatric Association. For more PsychEd, follow us on Twitter (@psychedpodcast) and Facebook. You can provide feedback by email at psychedpodcast@gmail.com.  For more information visit our website: psychedpodcast.org.

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This episode covers the topic of cultural psychiatry with expert guest Dr. Eric Jarvis, Staff Psychiatrist and Director of the Cultural Consultation Service and the First Episode Psychosis Program at the Jewish General Hospital in Montreal, Quebec and Associate Professor in the Department of Psychiatry at McGill University.   The learning objectives for this episode are as follows:   By the end of this episode, you should be able to… Define culture Describe how culture affects psychiatric care Outline the goal and structure of a Cultural Formulation Interview Evaluate clinical scenarios to determine whether to employ the Cultural Formulation Interview or seek a cultural consultation Define the three types of cultural concepts of distress, and compare these with DSM-5 nosology Discuss the concept of cultural competency  Explore the role of advocacy in psychiatric practice   Guest expert: Dr. Eric Jarvis Hosts: Dr. Sarah Hanafi (PGY3), Audrey Le (CC4) Audio editing by Dr. Sarah Hanafi (PGY3) Show notes by Dr. Sarah Hanafi (PGY3)   Interview Content: Introductions: 0:28 Learning objectives: 3:01 Definition of cultural psychiatry: 3:52 Definition of culture: 6:50 Disparities in mental health outcomes 12:48 The Cultural Formulation Interview (CFI) 15:59 Cultural concepts of distress 34:28 Cultural competency 40:46 Role of advocacy in psychiatry 48:04 Tips for those interested and training opportunities 51:26 Closing 61:01   Resources: McGill Summer Program in Social and Cultural Psychiatry McGill Advanced Study Institute in Cultural Psychiatry Society for the Study of Psychiatry and Culture Cultural Psychiatry Day   References: Cultural Formulation. (2017). In Diagnostic and statistical manual of mental disorders: DSM-5. Arlington, VA: American Psychiatric Association. Kirmayer, L. J., Fung, K., Rousseau, C., Lo, H. T., Menzies, P., Guzder, J., . . . Mckenzie, K. (2020). Guidelines for Training in Cultural Psychiatry. The Canadian Journal of Psychiatry, 070674372090750. doi:10.1177/0706743720907505 Kirmayer, L. J., Kronick, R., & Rousseau, C. (2018). Advocacy as Key to Structural Competency in Psychiatry. JAMA Psychiatry, 75(2), 119. doi:10.1001/jamapsychiatry.2017.3897  Kirmayer, L.J., Rousseau, C., Jarvis, G.E. and Guzder, J. (2008). The Cultural Context of Clinical Assessment. In Psychiatry (eds A. Tasman, J. Kay, J.A. Lieberman, M.B. First and M. Maj). doi:10.1002/9780470515167.ch4    CPA Note: The views expressed in this podcast do not necessarily reflect those of the Canadian Psychiatric Association. For more PsychEd, follow us on Twitter (@psychedpodcast), Facebook (PsychEd Podcast), and Instagram (@psyched.podcast). You can provide feedback by email at psychedpodcast@gmail.com. For more information visit our website at psychedpodcast.org.

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This episode covers Immigrant and Refugee mental health with not one, not two but three experts in the field: Dr. Lisa Andermann, Dr. Clare Pain, and Norma Hannant.   The learning objectives for this episode are as follows:   By the end of this episode, you should be able to: Explore the social, political and legal context of refugees and immigrants presenting with mental health concerns: Appreciate the specific mental health needs of refugee and immigrant populations in Canada. Describe the clinical approach to providing mental health care for this population: Produced and Hosted by: Dr. Sarah Hanafi (PGY 3), Weam Sieffien (CC3), and Shaoyuan (Randi) Wang (CC3)   Produced by: Dr. Sarah Hanafi (PGY 3), Weam Sieffien (CC3), and Shaoyuan (Randi) Wang (CC3)   Guest experts: Dr. Lisa Andermann, Dr. Clare Pain, Norma Hannant  Resources:  Immigrant and Refugee Mental Health Project (courses, community of practice and toolkits) Listen to Weam’s hands-on impressions of this resource in the post-credits of this episode References  Edmonston, B. (2016). Canadian immigration trends and patterns. Canadian Studies in Population, 43(1-2), 78-116.  Duffin, E. (2020). Immigration in Canada - Statistics & Facts. Statista. Retrieved 2020-06-16 from https://www.statista.com/topics/2917/immigration-in-canada/ Statistics Canada. (2019). Classification of admission category of immigrant. Retrieved 2020-06-16 from https://www23.statcan.gc.ca/imdb/p3VD.pl?Function=getVD&TVD=323293&CVD=323294&CLV=0&MLV=4&D=1 Robert, A. & Gilkinson, T. (2012). Mental health and well-being of recent immigrants in Canada: Evidence from the Longitudinal Survey of Immigrants to Canada. Citizenship and Immigration Canada. Retrieved 2020-06-16 from https://novascotia.cmha.ca/wp-content/uploads/2020/01/mental-health.pdf Ng, E. (2015). The healthy immigrant effect and mortality rates. Statistics Canada. Retrieved 2020-06-16 from https://www150.statcan.gc.ca/n1/pub/82-003-x/2011004/article/11588-eng.htm Immigrant and Refugee Mental Health Project. (n.d.). Retrieved from https://irmhp-psmir.camhx.ca/ Stats Canada 2016 Stats Canada 2017 Blair AH, Schneeberg A. Changes in the ‘healthy migrant effect’ in Canada: are recent immigrants healthier than they were a decade ago?. Journal of immigrant and minority health. 2014 Feb 1;16(1):136-42 Vang Z, Sigouin J, Flenon A, Gagnon A. The healthy immigrant effect in Canada: A systematic review. Population Change and Lifecourse Strategic Knowledge Cluster Discussion Paper Series/Un Réseau stratégique de connaissances Changements de population et parcours de vie Document de travail. 2015;3(1):4. Close C, Kouvonen A, Bosqui T, Patel K, O’Reilly D, Donnelly M. The mental health and wellbeing of first generation migrants: a systematic-narrative review of reviews. Globalization and health. 2016 Dec;12(1):47. Kirmayer LJ, Narasiah L, Munoz M, Rashid M, Ryder AG, Guzder J, Hassan G, Rousseau C, Pottie K. Common mental health problems in immigrants and refugees: general approach in primary care. Cmaj. 2011 Sep 6;183(12):E959-67 Betancourt, J.R., Green, A.R., Carrillo, J.E., & Ananeh-Firempong, O. (2003). Defining cultural competence: A practical framework for addressing racial/ethnic disparities in health and health care. Public Health Reports, 118, 293-302. Harris, M. & Fallot, R.D. (2001). Envisioning a Trauma-informed service system: A vital paradigm shift. New Directions in Mental Health Services, 89, 3-22. Chen AW, Kazanjian A, Wong H. Why do Chinese Canadians not consult mental health services: health status, language or culture?. Transcultural psychiatry. 2009 Dec;46(4):623-41. Durbin A, Lin E, Moineddin R, Steele LS, Glazier RH. Use of mental health care for nonpsychotic conditions by immigrants in different admission classes and by refugees in Ontario, Canada. Open Medicine. 2014;8(4):e136. Hansson, E., Tuck, A., Lurie, S., and McKenzie, K. for the Task Group of the Services Systems Advisory Committee, Mental Health Commission of Canada.  (2010). Improving mental health services for immigrant, refugee, ethno-cultural and racialized groups: Issues and options for service improvement. Available: http://www.mentalhealthcommission.ca/English/document/457/improving-mental-health-services-immigrant-refugee-ethno-cultural-and-racialized-groups Paniagua, F. (2014). Assessing and Treating Culturally Diverse Clients: A Practical Guide. Thousand Oaks, California: Sage CPA Note: The views expressed in this podcast do not necessarily reflect those of the Canadian Psychiatric Association.   For more PsychEd, follow us on Twitter (@psychedpodcast) and Facebook. You can provide feedback by email at psychedpodcast@gmail.com.  For more information visit our website: psychedpodcast.org.

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners.   In this episode, we begin to explore the neurobiology of the serotonin system — along with key pharmacological agents (SSRIs and classical psychedelics) that act on this system — with guest expert Dr. Robin Carhart-Harris, a neuroscientist and head of the Centre for Psychedelic Research at Imperial College London.   Our discussion is more theoretical than directly clinically relevant, striving to provide a mechanistic understanding of how serotonin functions within the brain and how serotonin-modulating drugs influence this system. The episode was inspired by a review published by our guest expert and Dr. David Nutt called “Serotonin and brain function: a tale of two receptors” (cited below). If you are interested in the topic, you might consider reading this review in full! Please note that the figures referenced during this episode can be accessed at https://journals.sagepub.com/doi/figure/10.1177/0269881117725915.   The learning objectives for this episode are as follows:    By the end of this episode, you should be able to…   Understand the general anatomy and function of the serotonin system, with a focus on the purported activity of the more common serotonin receptors and transporters. Describe the effects of serotonin reuptake inhibitors and how they lead to symptom improvement in mood and anxiety disorders, in addition to the mechanism of action of other serotonergic medications. Consider the two-pronged serotonin system conceptualized by Dr. Carhart-Harris, and understand how serotonergic agents (including SSRIs and classic psychedelics) and the concepts of active and passive coping fit within this theory.   Guest: Dr. Robin Carhart-Harris, a neuroscientist and head of the Centre for Psychedelic Research at Imperial College London.   Produced and hosted by: Dr. Chase Thompson (PGY3), Dr. Lucy Chen (Psychiatrist), Dr. Nikhita Singhal (PGY2)   Audio editing by: Dr. Chase Thompson   Infographic by: Dr Chase Thompson, Dr Nikhita Singhal   Interview Content:   00:18 - Introductions 3:00 - Learning objectives 4:10 - Introduction to serotonin 10:30 - 5HT1A receptors 24:30 - 5HT2A receptors 30:20 - Serotonin system operation under normal conditions 35:00 - Introduction of bipartite model / two divergent methods for addressing depression 42:20 - Parallels between psychological destabilization (through therapy) and the psychedelic effect  46:20 - Who should not have a psychedelic experience? Are psychedelics intrinsically psychotherapeutic or facilitative in nature? 50:20 - Brief discussion of the neuroimaging correlates of psychotherapeutic benefits from psychedelic experiences 58:40 - Discussion of why 2A agonists cause psychedelic effects but high serotonin release does not   Resources:   Carhart-Harris RL, Nutt DJ. Serotonin and brain function: a tale of two receptors. J Psychopharmacol. 2017;31(9):1091-1120. https://doi.org/10.1177/0269881117725915 Artigas F, Nutt DJ, Shelton R. Mechanism of action of antidepressants. Psychopharmacol Bull. 2002;36 Suppl 2:123-132. Antidepressants. In: Stahl SM. Stahl's Essential Psychopharmacology: Neuroscientific Basis and Practical Applications. 4th ed. Cambridge University Press; 2013:284-369. Beliveau V, Ganz M, Feng L, et al. A High-Resolution In Vivo Atlas of the Human Brain's Serotonin System. J Neurosci. 2017;37(1):120-128. https://doi.org/10.1523/JNEUROSCI.2830-16.2016 Carhart-Harris RL, Bolstridge M, Rucker J, et al. Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study. Lancet Psychiatry. 2016;3(7):619-627. https://doi.org/10.1016/S2215-0366(16)30065-7 Carhart-Harris RL, Leech R, Hellyer PJ, et al. The entropic brain: a theory of conscious states informed by neuroimaging research with psychedelic drugs. Front Hum Neurosci. 2014;8:20. https://doi.org/10.3389/fnhum.2014.00020 Carhart-Harris RL, Friston KJ. REBUS and the Anarchic Brain: Toward a Unified Model of the Brain Action of Psychedelics. Pharmacol Rev. 2019;71(3):316-344. https://doi.org/10.1124/pr.118.017160 Griffiths RR, Johnson MW, Carducci MA, et al. Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. J Psychopharmacol. 2016;30(12):1181-1197. https://doi.org/10.1177/0269881116675513 Griffiths RR, Richards WA, McCann U, Jesse R. Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance. Psychopharmacology (Berl). 2006;187(3):268-292. https://doi.org/10.1007/s00213-006-0457-5   CPA Note: The views expressed in this podcast do not necessarily reflect those of the Canadian Psychiatric Association. For more PsychEd, follow us on Twitter (@psychedpodcast), Facebook (PsychEd Podcast), and Instagram (@psyched.podcast). You can provide feedback by email at psychedpodcast@gmail.com. For more information, visit our website at psychedpodcast.org.

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This episode covers nutritional psychiatry with expert guest Dr. Laura LaChance, Staff Psychiatrist and Director of Outpatient Psychiatry at St. Mary’s Hospital Centre in Montreal, Quebec and Faculty Lecturer in the Department of Psychiatry at McGill University.   The learning objectives for this episode are as follows:   By the end of this episode, you should be able to…   1)      Define nutritional psychiatry 2)      Understand the mechanisms, common misconceptions, challenges, and current evidence supporting the role for nutrition in mental health 3)      Apply this understanding to clinical cases in psychiatry   Guest: Dr. Laura LaChance Hosts: Dr. Sarah Hanafi (PGY2), Dr. Nima Nahiddi (PGY2), Gray Meckling (CC3) Audio editing by Dr. Alex Raben (PGY5) Show notes by Gray Meckling   Interview Content:   ·       Introduction and learning objectives – 0:35 ·       Dr. Laura LaChance’s professional background – 1:50 ·       Definition of nutritional psychiatry and history of the field – 3:35 ·       Putative mechanisms through which nutrition is implicated in mental health – 7:00 ·       Common misconceptions surrounding the role for nutrition in mental health – 11:45 ·       Current evidence supporting the role for nutrition in the management of psychiatric illness – 16:00 ·       Case-based examples of nutrition in clinical psychiatry – 23:35 ·       Challenges to capitalizing on this mode of intervention in psychiatry – 32:30 ·       Taking a dietary history in the context of mental health – 34:50 ·       Future directions in the field of nutritional psychiatry – 41:20 ·       The gut-microbiome – 43:00 ·       Tips for those interested and how to get involved – 48:00 ·       Closing – 50:15   Resources:   ·       International Society for Nutritional Psychiatry Research ·       The Food & Mood Centre at Deakin University ·       Future Learn Online Course – Food and Mood: Improving Mental Health Through Diet and Nutrition ·       The Brain Food Academy ·       Dr. Drew Ramsey ·       Food as Medicine Update – Conference   Articles:   ·       Nutritional Psychiatry: The Gut-Brain Connection (Psychiatric Times) ·       Nutritional Psychiatry: Your Brain on Food (Harvard Health Publishing)   References:   ·       Adan, R. A., van der Beek, E. M., Buitelaar, J. K., Cryan, J. F., Hebebrand, J., Higgs, S., ... & Dickson, S. L. (2019). Nutritional psychiatry: Towards improving mental health by what you eat. European Neuropsychopharmacology. ·       Auction, Monique & LaChance, Laura & Cooley, Kieran & Kidd, Sean. (2019). Diet and Psychosis: A Scoping Review. Advances in Integrative Medicine. 6. S101. 10.1016/j.aimed.2019.03.292. ·       Firth J, Veronese N, Cotter J, Shivappa N, Hebert J, Ee C, Smith L, Stubbs B, Jackson S, Sarris J. What is the role of dietary inflammation in severe mental illness? a review of observational and experimental findings. Frontiers in psychiatry. 2019;10:350. ·       Firth, J., Carney, R., Stubbs, B., Teasdale, S. B., Vancampfort, D., Ward, P. B., ... & Sarris, J. (2018). Nutritional deficiencies and clinical correlates in first-episode psychosis: a systematic review and meta-analysis. Schizophrenia bulletin, 44(6), 1275-1292. ·       Francis HM, Stevenson RJ, Chambers JR, Gupta D, Newey B, Lim CK. A brief diet intervention can reduce symptoms of depression in young adults–A randomised controlled trial. PloS one. 2019;14(10). ·       Guu TW, Mischoulon D, Sarris J, Hibbeln J, McNamara RK, Hamazaki K, Freeman MP, Maes M, Matsuoka YJ, Belmaker RH, Jacka F. International Society for Nutritional Psychiatry Research Practice Guidelines for Omega-3 Fatty Acids in the Treatment of Major Depressive Disorder. Psychotherapy and psychosomatics. 2019;88(5):263-73. ·       Jacka, F. N. (2017). Nutritional psychiatry: where to next?. EBioMedicine, 17, 24-29. ·       Jacka F, O’Neil A, Opie R, et al. A randomized controlled trial of dietary improvement for adults with major depression (the SMILES trial). BMC Med. 2017; 15:23. ·       LaChance, L. R., & Ramsey, D. (2018). Antidepressant foods: An evidence-based nutrient profiling system for depression. World journal of psychiatry, 8(3), 97–104. https://doi.org/10.5498/wjp.v8.i3.97 ·       Lachance, L., & Ramsey, D. (2015). Food, mood, and brain health: Implications for the modern clinician. Missouri medicine, 112(2), 111. ·       Marx W, Moseley G, Berk M, Jacka F. Nutritional psychiatry: the present state of the evidence. Proc Nutr Soc. 2017;76: 427-436. ·       Lakhan, S. E., & Vieira, K. F. (2010). Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review. Nutrition journal, 9(1), 42. ·       Mörkl S, Butler MI, Holl A, Cyran JF, Dinan TG. Probiotics and the Microbiota-Gut-Brain Axis: Focus on Psychiatry. Current Nutrition Reports. 2020 May 13. ·       Mörkl, S., Wagner-Skacel, J., Lahousen, T., Lackner, S., Holasek, S. J., Bengesser, S. A., ... & Reininghaus, E. (2020). The role of nutrition and the gut-brain axis in psychiatry: a review of the literature. Neuropsychobiology, 79(1-2), 80-88. ·       Parletta N, Zarnowiecki D, Cho J, Wilson A, Bogomolova S, Villani A, Itsiopoulos C, Niyonsenga T, Blunden S, Meyer B, Segal L. A Mediterranean-style dietary intervention supplemented with fish oil improves diet quality and mental health in people with depression: A randomized controlled trial (HELFIMED). Nutritional neuroscience. 2019 Jul 3;22(7):474-87. ·       Sarris J, Logan AC, Akbaraly TN, et al. Nutritional medicine as mainstream in psychiatry. Lancet Psychiatry. 2015;2: 271-274.   CPA Note: The views expressed in this podcast do not necessarily reflect those of the Canadian Psychiatric Association.   For more PsychEd, follow us on Twitter (@psychedpodcast), Facebook (PsychEd Podcast), and Instagram (@psyched.podcast). You can provide feedback by email at psychedpodcast@gmail.com. For more information visit our website at psychedpodcast.org.