
Depresh Mode with John Moe
Join host John Moe (The Hilarious World of Depression) for honest, relatable, and, yes, sometimes funny conversations about mental health. Hear from comedians, musicians, authors, actors, and other top names in entertainment and the arts about living with depression, anxiety, and many other common disorders. Find out what they’ve done to address it, what worked, and what didn’t. Depresh Mode also features useful insights on mental health issues with experts in the field. It’s honest talk from people who have been there and know their stuff. No shame, no stigma, and more laughs than you might expect.
Latest episodes

Aug 12, 2024 • 40min
Susan Cain on Reaching a Quiet Life
Introverts around the world celebrated, quietly, when Susan Cain’s book, Quiet: The Power of Introverts in a World That Can’t Stop Talking, became a #1 best-seller back in 2012. Her next book, Bittersweet: How Sorrow and Longing Make Us Whole, also went to #1. Now Cain is back with an audio series, A Quiet Life in Seven Steps, about how to reach a quieter mindset. In this interview, we talk through some of those steps and the challenges one might face in trying to get there.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlinesThe Depresh Mode newsletter is available twice a week. Subscribe for free and stay up to date on the show and mental health issues. https://johnmoe.substack.com/John’s acclaimed memoir, The Hilarious World of Depression, is now available in paperback. https://us.macmillan.com/books/9781250209566/thehilariousworldofdepressionFind the show on X @depreshpod and Instagram @depreshpod.John is on X @johnmoe.

Aug 5, 2024 • 41min
Gut Health, Resilience, and What the Heck Is TMS Anyway?
The gut microbiome, that little ecosystems of bacteria and microorganisms in your body, and your mental health are more closely related than we may have thought. Dr. Aparna Church led a study that points out the connection between a person’s stress resilience and the composition of their gut microbiome. She joins us and offers advice on how to eat best for your own stress management. Then host John Moe thoroughly unpacks and demystified TMS (transcranial magnetic stimulation) therapy. He explains what it is, what the different types of it are, what actually happens when you go, how it works on your brain, and what kind of results to expect.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlinesThe Depresh Mode newsletter is available twice a week. Subscribe for free and stay up to date on the show and mental health issues. https://johnmoe.substack.com/John’s acclaimed memoir, The Hilarious World of Depression, is now available in paperback. https://us.macmillan.com/books/9781250209566/thehilariousworldofdepressionFind the show on X @depreshpod and Instagram @depreshpod.John is on X @johnmoe.

Jul 29, 2024 • 46min
Mike Doughty Was Recently Hospitalized for Depression Twice. It Helped.
It was two years into a vicious cycle of depression and Mike Doughty was falling apart. He was taking more Ambien than he had been prescribed, importing huge boxes of the stuff from India, waking up to find packs of cigarettes, candy wrappers, and pizza boxes with no memory of leaving his Memphis home to make such purchases. He was convinced something was deeply wrong with his heart even though every doctor said there wasn’t. Finally, he checked into an in-patient facility that turned out to be wonderful and productive. Then he checked out. Then Mike, a recovering addict, started drinking heavily and smoking weed. Then he checked back in again. Mike Doughty is showing improvement now and talks about his treatment, his recovery, and touring again with his band Soul Coughing again 24 years after a bitter breakup.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlinesThe Depresh Mode newsletter is available twice a week. Subscribe for free and stay up to date on the show and mental health issues. https://johnmoe.substack.com/John’s acclaimed memoir, The Hilarious World of Depression, is now available in paperback. https://us.macmillan.com/books/9781250209566/thehilariousworldofdepressionFind the show on X @depreshpod and Instagram @depreshpod.John is on X @johnmoe.

Jul 22, 2024 • 42min
Reframing Your Memories, Even the Terrible Ones, To Help Your Mental Health
Memories are like the radiant light and heat of the sun. They’re always coming at us, inescapable. But like that radiant light and heat, memories can be harnessed and converted into a fuel that can provide power. That’s the thinking behind cognitive reminiscence therapy (CRT), the practice of revisiting, reexamining, and reframing your memories to get to a better place psychologically. Dr. David Hallford of Deakin University in Australia joins us to share his research into CRT and his findings that issues like depression, self-esteem, and optimism improve considerably when therapeutic practices are put in place. He also advises on how we could do exactly that to live better lives.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlinesThe Depresh Mode newsletter is available twice a week. Subscribe for free and stay up to date on the show and mental health issues. https://johnmoe.substack.com/John’s acclaimed memoir, The Hilarious World of Depression, is now available in paperback. https://us.macmillan.com/books/9781250209566/thehilariousworldofdepressionFind the show on X @depreshpod and Instagram @depreshpod.John is on X @johnmoe.

Jul 15, 2024 • 46min
Life Inside a Psych Unit and Therapy for Rock Bands
One South: Portrait of a Psych Unit is an HBO documentary about life inside an in-patient facility in Queens that specializes in helping people of college age who are in acute crisis. The filmmakers, Alexandra Shiva and Lindsay Megrue, introduce a variety of patients who have been through experiences such as suicide attempts or drug overdoses and they spotlight the unique care being administered. In-patient care has certainly been depicted often in movies and TV but this is one of few documentary approaches. Then, we’re joined by Sarah Souder Johnson, a clinician at Sentier Psychotherapy in Saint Paul, Minnesota who offers therapy for rock bands. We talk about the challenges and rewards of that and what it can teach all of us about families and groups even if we’re not a wicked guitar soloist.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlinesThe Depresh Mode newsletter is available twice a week. Subscribe for free and stay up to date on the show and mental health issues. https://johnmoe.substack.com/John’s acclaimed memoir, The Hilarious World of Depression, is now available in paperback. https://us.macmillan.com/books/9781250209566/thehilariousworldofdepressionFind the show on X @depreshpod and Instagram @depreshpod.John is on X @johnmoe.

Jul 8, 2024 • 53min
Gracie Gold, Olympic Figure Skater and Human with Mental Illness
In terms of achievement, Gracie Gold had it all: Olympic medal, world championships, beloved celebrity at the pinnacle of an incredibly competitive and difficult field. She even became friends with Taylor Swift. Unfortunately, in terms of mental health problems, she also had it all: eating disorders, body dysmorphia, depression, anxiety, suicidal ideation, ADHD, and OCD. Despite those challenges, her career required dressing up in glamorous outfits and perfect hair and makeup and going out to skate under the spotlights and be judged. It all got to be too much and Gracie fell apart, finally got treatment, and began a long road to recovery. Gracie has a new book, titled OutOfShapeWorthlessLoser: A Memoir of Figure Skating, F*cking Up, and Figuring It Out.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlinesThe Depresh Mode newsletter is available twice a week. Subscribe for free and stay up to date on the show and mental health issues. https://johnmoe.substack.com/John’s acclaimed memoir, The Hilarious World of Depression, is now available in paperback. https://us.macmillan.com/books/9781250209566/thehilariousworldofdepressionFind the show on X @depreshpod and Instagram @depreshpod.John is on X @johnmoe.

Jul 1, 2024 • 49min
The Decemberists’ Colin Meloy Opens Up About Lifelong Anxiety, Impostor Syndrome
The Decemberists have been making memorable, popular, and critically acclaimed music for over twenty years and for that entire time, lead singer and songwriter Colin Meloy has battled the feeling that he’s secretly a fraud. And the more success he’s had with his career, the more he’s been at the head of a large organization upon which people earn their livelihood, the more that feeling grew. Colin hasn’t gone into much detail about this interviews over the years but he does so in this honest and vulnerable conversation that also touches on his long-standing issues with anxiety and the formative challenge of a parent who discouraged him from pursuing the arts as a profession.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlinesThe Depresh Mode newsletter is available twice a week. Subscribe for free and stay up to date on the show and mental health issues. https://johnmoe.substack.com/John’s acclaimed memoir, The Hilarious World of Depression, is now available in paperback. https://us.macmillan.com/books/9781250209566/thehilariousworldofdepressionFind the show on X @depreshpod and Instagram @depreshpod.John is on X @johnmoe.

Jun 24, 2024 • 56min
A Regular Guy, Managing Trauma, Who Happens to Be Paul Scheer
Trauma and comedy wouldn’t seem to have a lot in common but they do have one thing: Paul Scheer. You may know Paul from TV shows like the comedy The League or from his podcasts like How Did This Get Made. In this deeply personal, vulnerable, and - yes - funny interview and in his new memoir, Joyful Recollections of Trauma, Paul Scheer recounts tales of the repeated physical and mental abuse he and his mom received from his stepfather. He also recounts how he has learned to process these and other traumatic events, draw strength from them, and become a better and stronger father, husband, and guy.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlinesThe Depresh Mode newsletter is available twice a week. Subscribe for free and stay up to date on the show and mental health issues. https://johnmoe.substack.com/John’s acclaimed memoir, The Hilarious World of Depression, is now available in paperback. https://us.macmillan.com/books/9781250209566/thehilariousworldofdepressionFind the show on X @depreshpod and Instagram @depreshpod.John is on X @johnmoe.

Jun 17, 2024 • 54min
Comedian Liz Miele on Depression, Trauma, Violence, and Live On-Stage Panic Attacks
Liz Miele has headlined on comedy stages around the world and produced numerous stand-up specials. It’s an impressive career that began at Manhattan open mics when she was 16 years old. We have a wide-ranging conversation with Liz about her recent depressive episode, the panic attacks that have been going on for years including in the middle of her sets, and her family history. Both of Liz’s grandmothers died by suicide before she was born and her home growing up featured a lot of stress, intensity, and some violence. Liz’s latest special, available on YouTube, is titled Murder Sheets.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlinesThe Depresh Mode newsletter is available twice a week. Subscribe for free and stay up to date on the show and mental health issues. https://johnmoe.substack.com/John’s acclaimed memoir, The Hilarious World of Depression, is now available in paperback. https://us.macmillan.com/books/9781250209566/thehilariousworldofdepressionFind the show on X @depreshpod and Instagram @depreshpod.John is on X @johnmoe.

Jun 10, 2024 • 44min
Comedian Sierra Katow on Big Time Achievement and Persistent Depression
Just because someone’s depressed, doesn’t mean they can’t achieve great things. Just because someone can achieve great things, doesn’t mean they aren’t depressed. You may already know these facts, especially if you’ve been listening to our show doe a while, but they bear repeating because they can be easy to forget. Sierra Katow has a new standup special, her first, called Funt (referring to the Fun Aunt she hopes to be) and she joins us to talk about the depression that has been there since she was a kid and which she’s had to work to manage ever since. It’s an honest and very funny conversation.Thank you to all our listeners who support the show as monthly members of Maximum Fun.Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.Help is available right away.The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALKCrisis Text Line: Text HOME to 741741.International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlinesThe Depresh Mode newsletter is available twice a week. Subscribe for free and stay up to date on the show and mental health issues. https://johnmoe.substack.com/John’s acclaimed memoir, The Hilarious World of Depression, is now available in paperback. https://us.macmillan.com/books/9781250209566/thehilariousworldofdepressionFind the show on X @depreshpod and Instagram @depreshpod.John is on X @johnmoe.
Remember Everything You Learn from Podcasts
Save insights instantly, chat with episodes, and build lasting knowledge - all powered by AI.