
Medicine Redefined
Dr. Darsh Shah & Dr. Altamash Raja interview practitioners who challenge the norm and promote health during a time when the healthcare system is broken. Learn how experts in the fields of sleep, nutrition, exercise, stress resilience, rehabilitation, lifestyle medicine, and others are using new-age thinking to move the needle forward and redefine medicine as we know it.
Latest episodes

Mar 25, 2024 • 1h 23min
148. Physique Optimization: Psychology, Longevity & Lifestyle (Part 2) | Joe Farese
Joe Farese is a natural-for-life pro bodybuilder who has competed for the last 36 years consecutively. He has also worked over the past 36 years as a trainer and health coach for populations ranging from young athletes to seniors.
Joe's recent bodybuilding resume includes:
2021 WNBF Pro Mr. Universe winner
2021 and 2022 Pro Masters Mr. America winner
2023 Pro Mr. America lightweight class winner and Grandmasters (50+) Mr America class winner
In this episode, we discuss:
Sleep and distress tolerance in relation to physique transformation
The power of social connection
Longevity in bodybuilding
Injury prevention
Drug testing and steroids in bodybuilding
The psychology of bodybuilding
Body dysmorphia and body image
Resources mentioned in the show:
Mike Israetel on sleep for muscle growth (Modern Wisdom)
Joe on the three kinds of performance intelligence: mind, body, and emotion

Mar 18, 2024 • 1h 47min
147. Physique Optimization: Muscle Building & Fat Loss (Part I) | Joe Farese
Joe Farese is a natural-for-life pro bodybuilder who has competed for the last 36 years consecutively. He has also worked the past 36 years as a trainer and health coach for populations ranging from young athletes to seniors.
Joe's recent bodybuilding resume includes:
2021 WNBF Pro Mr. Universe winner
2021 and 2022 Pro Masters Mr. America winner
2023 Pro Mr. America lightweight class winner and Grandmasters (50+) Mr America class winner
In this episode, we discuss:
-Background in bodybuilding and coaching
-Competing at a high level
-Pros/Cons of “bodybuilding mentality”
-Specific training philosophies
-Traditional bodybuilding vs “functional” training
-Bodybuilding nutrition

Mar 11, 2024 • 1h 13min
146. The Rise of the Self-Determined Physician | Jimmy Turner, MD
Dr. Jimmy Turner is an academic anesthesiologist, entrepreneur, author, and life coach. He obtained his medical degree from Wake University and then completed an Anesthesia residency at the same institution. Subsequently, he completed a Regional Anesthesia and Acute Pain Medicine fellowship. After his training, he stayed on within the Department of
Anesthesia and now holds the title of Associate Professor.
Dr. Turner is passionate about teaching doctors how to create the time, financial
freedom, and mindset shifts they need to create a life they love, which he does
through books, podcasts, and his coaching program.
In this episode, we discuss:
Jimmy's origin story
Disability insurance
The arrival fallacy
Shift from physician burnout to entrepreneur burnout
the importance of setting boundaries
Jimmy’s hell yes policy
Revamping medical education to empower physicians, help promote autonomy, and minimize the risk of burnout
What makes a self-determined physician
Jimmy's FREE Book
Find Jimmy Turner:
Money Meets Medicine
The Physician Philosopher
Podcasts
Books
Coaching

Mar 4, 2024 • 35min
145. Progress Note #16: Osteopathic (DO) vs. Allopathic (MD) Medicine & The Bias Against DOs
Drs. Altamash and Darsh are both DOs - osteopathic physicians. They break down the recent biases against this branch of medicine and explain the education process as well as similarities and differences to their allopathic (MD) peers.
Mentioned in the show:
Hasan Minhaj Stand-Up
"Somebody who does something other than osteopathy"

Feb 26, 2024 • 1h 28min
144. Minimalist Shoes, Running Mechanics & Barefoot Training | Irene Davis, PhD, PT
Irene Davis, PhD, PT, is a Professor in the School of Physical Therapy and Rehabilitation Science in the Morsani College of Medicine at the University of South Florida. Prior to this, she was the founding Director of the Spaulding National Running Center in the Department of Physical Medicine and Rehabilitation at Harvard Medical School. Dr. Davis received her Bachelor of Science in Exercise Science from the University of Massachusetts, and in Physical Therapy from the University of Florida. She earned her Masters degree in Biomechanics from the University of Virginia, and her PhD in Biomechanics from Pennsylvania State University. Her research is focused on the relationship between lower extremity structure, mechanics and injury and extends to the development of interventions to alter faulty mechanics through gait retraining. Her interests also include the effect of minimal footwear on mechanics and injury. She has given over 350 lectures both nationally and internationally and authored 160 publications on the topic of lower extremity mechanics during walking and running gait. She has been named one of the 50 Most Influential People in Running. She is the current President of the American College of Sports Medicine.
In this episode, we discuss:
Dr. Davis’ journey into PT and how she developed a passion into minimalist footwear
and training.
Foot anatomy and the importance of spending time training and addressing the foot
core
Various foot strike patterns and force distribution
Foot types, and shoe types such as motion control, stability, etc.
The role of minimalist footwear training and how it applies to clinical medicine
Early and lifetime exposure to barefoot training
Studies mentioned in the show:
Injury reduction effectiveness of assigning running shoes based on plantar shape in Marine Corps basic training
Injury reduction effectiveness of selecting running shoes based on plantar shape
Injury-reduction effectiveness of prescribing running shoes on the basis of foot arch height: summary of military investigations
Foot strike patterns and collision forces in habitually barefoot versus shod runners
Walking in Minimalist Shoes Is Effective for Strengthening Foot Muscles
The foot core system: a new paradigm for understanding intrinsic foot muscle function
The effect of a 12-week custom foot orthotic intervention on muscle size and muscle activity
Other resources mentioned in the show:
Born to Run by Chris McDougall
Follow Dr. Davis:
Twitter @IreneSDavis

Feb 19, 2024 • 1h 30min
143. Solving the Mental Health Crisis, Intuitive Mental Health & The Human Condition | Ravi Hariprasad, MD, MPH
Ravi Hariprasad, MD, MPH, is the founder and CEO of Intuitive Mental Health, a start up focused on partnering with primary care physicians to deliver comprehensive and personalized mental health support. Dr. Hariprasad obtained his medical degree of the University of Pennsylvania and completed his Masters in Public Health as well as his psychiatry residency at Harvard University. Dr. Hariprasad is well versed in both Western medicine as well as holistic and complementary perspectives such as Ayurveda. His early experience as an engineer and an entrepreneur have helped him understand system design, root cause analysis, and solution development and implementation.
Ravi Hariprasad LinkedIn
Mentioned in the show:
Intuitive Mental Health
Intuitive Psychiatry
Episode 127 - Ayurvedic Principles (Jyoti Patel, MD)
Episode 86 - Ayurveda in Modern Life (Shivani Gupta, PhD)
Jean Paul Sartre
Viktor Frankl
Stoicism
Selective Serotonin Reuptake Inhibitors (SSRIs)

Feb 12, 2024 • 1h 1min
142. The Med Matrix & AI in Medical Education | Deepak Melwani
Deepak Melwani is a serial entrepreneur and a 3rd year medical student at Midwestern University Chicago of Osteopathic Medicine, with a robust background in computer science. Before starting medical school, Deepak co-founded a retail software service, scaling it to achieve millions in revenue. His passion lies in leveraging business and technology to reach and impact lives globally. Deepak is deeply committed to integrating these interests with the transformative power of healthcare to profoundly influence individual lives. As a founding partner of Med Matrix, he is at the forefront of innovating the educational landscape for health professional students, revolutionizing their daily study routines.
Social Media:
Instagram
Twitter
Mentioned in the Show:
The Med Matrix (code 'MEDREDEFINED' for 15$ off 1st month)
Episode 76 - Rami Wehbi
MatchDay Health

Feb 5, 2024 • 49min
141. Progress Note #15: 2024 Health Trends, 100 Grams of Protein in One Meal & Visceral Fat Causing Joint Pain
Drs. Darsh and Altamash sit down to discuss what they beleive will be the biggest health trends of 2024, a recent paper in the Cell Reports Medicine about maximizing protein consumption for muscle growth, and a paper discussing the role of visceral fat in joint pain.
SIGN UP FOR OUR NEWSLETTER!
Mentioned in the Show:
Episode 4 - Shawn Arent (Nutrient Timing)
Episode 130 - Jonathon Baktari (Digital Health)
Episode 114 - Jo Bhakdi (AI in Medicine)
Episode 104 - Bill Cromwell (Cardiovascular Disease)
Episode 8 - Patrick Finan (Pain)
The anabolic response to protein ingestion... (Cell Reports Medicine)
Visceral adiposity is associated with pain...
Williamsburg Bathhouse
DexaFit
You Are What You Eat (Netflix)

Jan 29, 2024 • 57min
140. A Change of Heart: The Pulse on Life After Transplant | Alin Gragossian, DO
Dr. Alin Gragossian completed a residency program in Emergency Medicine at Drexel University, where she cultivated the skills required to manage critical and time-sensitive diagnoses. Following her residency, Dr. Gragossian pursued a 2-year multidisciplinary fellowship in Critical Care Medicine at Mount Sinai Hospital in New York City. Her experiences in these environments equipped her with a unique insight into the intricacies of managing critical cardiac conditions.
Remarkably, Dr. Gragossian's personal journey has been deeply intertwined with her professional pursuits. In 2019, she underwent an urgent heart transplant herself after being diagnosed with familial dilated cardiomyopathy, a life-changing experience that gave her a unique understanding of the patient's perspective.
Presently, Dr. Gragossian is an Intensivist through Equum Medical. Additionally, she holds the position of Associate Medical Director at Donor Network West, where she guides the organization's donor management initiatives. Furthermore, her contributions extend to the realm of medical technology as a consultant for various medical technology companies, where she leverages her expertise to advance medical innovation in critically ill patients.
Most recently, Dr. Gragossian's dedication to advocacy has earned her the esteemed role of Chair of the American Society of Transplantation's Transplant Community Advisory Council. Here, she helps shape the future of transplant medicine and health education for patients and caregivers.
Things we discuss in the show:
Alin's genesis story
Illness to heart transplant
Lessons learned from being at death's door
Alin's future
Follow Dr. Gragossian:
LinkedIn
Instagram
Blog
Podcast

Jan 22, 2024 • 1h 1min
139. Behind the Scenes of News Outlets, Journalist Incentives, Biased Media, Incorporating Feedback & Tangle News | Isaac Saul
Isaac Saul is the reporter and founder of Tangle, an independent, ad-free, non-partisan politics newsletter that summarizes the best arguments from the left and right on the news of the day. Isaac is based in Philadelphia, PA, and grew up in the politically divisive Bucks County. Before Tangle, Isaac worked joined the The Pitt News during my sophomore year of college at the University of Pittsburgh and served as the sports editor. He then worked at the Huffington Post as well as along side Ashton Kutcher to build A Plus, one of the world's largest positive news outlets. His work at Tangle has been recognized by The New York Times, Forbes, The Hustle, Substack and many others as one of the most successful politics newsletters on the internet.
Mentioned in the show:
Tangle News
Non-Partisan Perspective on the Israel-Hamas War
10 Thoughts on What is Happening in Israel
Hasan Minhaj Rebuttal to New Yorker
Succession