People Behind the Science Podcast Stories from Scientists about Science, Life, Research, and Science Careers

Dr. Marie McNeely, featuring top scientists speaking about their life and c
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Jun 24, 2019 • 43min

507: Investigating How Frogs are Impacted by Climate Change, Fungal Disease, and Selection Pressures - Dr. Cori Richards-Zawacki

Dr. Cori Richards-Zawacki is an Associate Professor in the Department of Biological Sciences and Director of the Pymatuning Lab of Ecology at the University of Pittsburgh. Cori studies topics in ecology, evolutionary biology, behavior, and conservation in frogs. In particular, she is working to understand how frogs use different body forms, colors, and other features to survive partially on land and partially in water. When she’s not working and doing research, Cori enjoys spending time outside with her husband and two young daughters. She likes to play soccer, hike, go mountain biking, and do other outdoor activities. Cori received her Bachelor’s degree in engineering and biology as well as her PhD in ecology and evolutionary biology both from the University of Michigan. She conducted postdoctoral research at the Smithsonian Institute and the University of California, Berkeley. Cori next served on the faculty at Tulane University prior to joining the faculty at the University of Pittsburgh in 2015. In our interview, Cori shares more about her life and science.
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Jun 17, 2019 • 35min

506: Sage Scientist Developing New Drugs for Depression and Other Neurological Diseases - Dr. Jim Doherty

Dr. Jim Doherty is Chief Research Officer at Sage Therapeutics, a clinical-stage biopharmaceutical company committed to developing and commercializing novel medicines to treat life-altering central nervous system disorders. Jim and his colleagues are focused on developing new treatments for different brain disorders including psychiatric, neurodegenerative, and movement disorders. Outside of science, Jim enjoys traveling, seeing cool new sites, and exploring the history of different places with his wife and two kids. He also enjoys participating in a variety of team sports like golf, softball, and ultimate frisbee leagues. Jim received his B.A. in biology from the University of Delaware and his Ph.D. in neuroscience from Georgetown University. Next, he conducted postdoctoral research at Emory University Medical School and subsequently served on the faculty at Emory for about two years. Prior to joining the team at Sage in 2014, Jim worked for about eleven years at AstraZeneca Pharmaceuticals. In our interview Jim shares more about his life and science.
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Jun 10, 2019 • 25min

505: Developing Drugs to Treat Lupus Nephritis and Other Rare Diseases - Dr. Neil Solomons

Dr. Neil Solomons is Chief Medical Officer and Co-Founder of Aurinia Pharmaceuticals, a clinical stage biopharmaceutical company focused on developing and commercializing therapies in disease areas of high unmet medical need. Neil is working to develop a drug to treat a rare autoimmune disease called lupus nephritis. In lupus nephritis, there is inflammation of the kidneys that can result in kidney failure, need for dialysis, or kidney transplant. Currently, there are no FDA-approved therapies for this disease, and the team at Aurinia is excited to be in the final stages of developing a drug called Voclosporin to treat lupus nephritis. Outside of research, Neil is an obsessive soccer fan, and he has been avidly watching English Premier League games since he was a child. He also enjoys playing the guitar and spending time with his family. Neil was awarded his Medical Degree from the University of London’s Guys Hospital Medical School. Afterwards, he worked as a physician in London and completed specialist training in anesthesia and intensive care. Neil held positions at Roche Pharmaceuticals, Aspreva Pharmaceuticals, and Vifor Pharma before co-founding Aurinia. In our interview Neil will tell us more about his life and science.
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Jun 3, 2019 • 39min

504: Researching Age-Related Retinal Degeneration Diagnostics and Therapeutics - Dr. Anne Fung

Dr. Anne Fung is the Global Development Lead for the Port Delivery System with Ranibizumab and Lucentis at Genentech. She is also a practicing retina specialist and researcher at Pacific Eye Associates and California Pacific Medical Center in San Francisco. Macular degeneration is a degenerative condition of a portion of the retina in the eye. This disease generally affects older adults. While there are some amazing medicines that can help people with macular degeneration, these medicines must be injected into the eye every 4-6 weeks. Anne is working on a tiny implant that serves as a reservoir for medicine so it can be slowly released over 6 months or more. They are currently investigating how long this implant can effectively treat the disease. Outside of science, Anne loves practicing yoga, as well as reading, listening to podcasts, and listening to audiobooks on a variety of topics including business, organizations, and psychology. Anne received her undergraduate degree from Wellesley College and her Medical Degree from Cornell University. She completed her residency in ophthalmology at Stanford University School of Medicine and then pursued a Medical Retina Fellowship at the Bascom Palmer Eye Institute and the University of Miami Miller School of Medicine. Anne worked in clinical practice for ten years before joining the team at Genentech in 2014. Anne is a Board Certified Ophthalmologist and is a Fellow of the American Academy of Ophthalmology. In our interview she shares more about her life and science.
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May 27, 2019 • 36min

503: Identifying Genetic Variants and Phenotypic Traits Associated with Parkinson's Disease - Dr. Karl Heilbron

Dr. Karl Heilbron is a Scientist I in Statistical Genetics at 23andMe. He focuses on identifying genetic variants that are associated with diseases such as Parkinson’s disease. Once variants are identified, he conducts more targeted analyses to better understand the genetic basis of disease. When he’s not working, Karl enjoys staying active by playing soccer and other sports. In addition, he has been having fun staying in touch with old friends by playing Dungeons and Dragons together online. Karl received his Bachelor's degree in Evolutionary Science from Western University where he was awarded the Western Gold medal for highest course average. He next attended The University of Oxford where he earned his Ph.D. degree in evolutionary genomics. Karl was awarded a Julie Payette Research Scholarship from The Natural Sciences and Engineering Research Council of Canada for his graduate work. Afterwards, Karl conducted postdoctoral research in computational biology at 23andMe before accepting his current position there. In our interview Karl will tell us more about his life and science.
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May 20, 2019 • 35min

502: Investigating the Impacts of the Gut Microbiome on Immunotherapy Cancer Treatments - Dr. Jennifer Wargo

Dr. Jennifer Wargo is an Associate Professor in the Department of Surgical Oncology at The University of Texas MD Anderson Cancer Center and a Stand Up To Cancer researcher. Jennifer is a physician scientist, and this means she splits her time between providing care to patients and doing research to find better ways of treating disease. Specifically, Jennifer performs surgeries and treats patients one day each week. She spends the rest of her week studying how to treat patients with cancer and how cancer may ultimately be prevented. When she’s not doing research or treating patients, Jennifer enjoys spending quality time with her family. Some of their favorite activities include going for walks, biking, hiking, and visiting the beach. Jennifer also likes to explore her creative side through art and photography, as well as to be active through running, biking, yoga, and surfing. She received her A.S. degree in nursing and B.S. degree in biology from Gwynedd-Mercy College. Afterwards, Jennifer attended the Medical College of Pennsylvania where she earned her M.D. Jennifer completed her Clinical Internship and Residency in General Surgery at Massachusetts General Hospital. Next, Jennifer was a Research Fellow in Surgical Oncology at the University of California, Los Angeles. She then accepted a Clinical Residency in General Surgery at Massachusetts General Hospital. From 2006-2008, Jennifer was a Clinical Fellow in Surgical Oncology at the National Cancer Institute of the National Institutes of Health. She then served on the faculty at Massachusetts General Hospital and Harvard University. In 2012, Jennifer received her MMSc. degree in Medical Science from Harvard University. Jennifer joined the faculty at The University of Texas MD Anderson Cancer Center in 2013. She is Board Certified by the American Board of Surgery, and she has received numerous awards and honors throughout her career. These have included the R. Lee Clark Prize and Best Boss Award from the MD Anderson Cancer Center, the Rising STARS and The Regents’ Health Research Scholars Awards from the University of Texas System, the Outstanding Young Investigator and Outstanding Investigator Awards from the Society for Melanoma Research, as well as a Stand Up To Cancer Innovative Research Grant for her microbiome work. She has also received other awards for excellence in teaching, research, and patient care. In our interview, Jennifer will tell us more about her life and science.
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May 13, 2019 • 32min

501: Modeling Social Systems to Inform Interventions and Impact Policies - Dr. Brian Goode

Dr. Brian Goode is a Research Scientist at the Fralin Life Science Institute at Virginia Tech, formerly the Biocomplexity Institute. Brian’s background is in engineering, and his current research aims to understand how data-driven and theoretical models can be applied to the real world. For example, in one project, he is working to predict outcomes for people and their families using data from their first nine years of life. Their goal is to make the best models they can, identify the considerations needed to apply these models to reality, and then determine how their models can be used to help craft interventions and policies. Lately, Brian has been spending his weekends with his wife repairing and preparing their sailboat. He learned how to sail during graduate school, and he is excited to be nearly ready to set sail in his own sailboat. Brian received his B.S. and Ph.D. in mechanical engineering from Virginia Tech. He was awarded an Office of Naval Research assistantship to complete his doctoral work. Afterwards, Brian went on a working holiday visa to Australia where he was a Field Engineer for Infrastructure Management Group, a bartender in Port Douglas, Queensland, and started freelance web developing while traveling. He then became an English Teacher in Thailand, and a Logistics Engineer at JB Hunt Transport Services, Inc. before returning to Virginia Tech to accept a postdoctoral fellowship. In 2016, Brian transitioned into his current position as a Research Scientist at Virginia Tech, and in 2017, he was awarded an Innovation Award from the Fragile Families Challenge held at Princeton University. In our interview, Brian will tell us more about his life and research.
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May 6, 2019 • 43min

500: Deep Sea Explorer Seeking Solutions to Stop Marine Pollution - Dr. Edith Widder

Dr. Edith Widder is Co-Founder, CEO, and Senior Scientist at the Ocean Research & Conservation Association (ORCA), a scientific based conservation nonprofit. ORCA aims to find upstream solutions to the pollution problems that are plaguing our oceans. They use science-based approaches to determine where pollution is coming from and what can be done to stop it. When Edie isn’t doing science, she loves immersing herself in nature through hiking and kayaking. She also enjoys visiting museums, especially art museums. Edie received a BS in Biology from Tufts University and worked as a Laboratory Technician at Harvard Medical School before enrolling in graduate school. She attended UC, Santa Barbara where she earned a MS in biochemistry and a PhD in Neurobiology. Prior to founding ORCA, Edie worked for 16 years as a senior scientist at Harbor Branch Oceanographic Institute. Edie has received numerous awards and honors throughout her career, including a MacArthur Fellowship, the 2018 Explorers Club Citation of Merit, Induction into the Women Diver’s Hall of Fame, and Certifications as a research pilot for single-person submersibles, including wasp, Deep Rover, and Deep Worker. Edie also has the honor of having her underwater images featured on seven of the ten recently released bioluminescence stamps from the U.S. Postal Service. In our interview, Edie shares more about her life and science.
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Apr 29, 2019 • 44min

499: Developing New Vaccines to Prevent Infectious Diseases from Bacteria - Dr. Annaliesa Anderson

Dr. Annaliesa Anderson is Vice President and Chief Scientific Officer of Bacterial Vaccines within Vaccine Research and Development at Pfizer Inc. In the lab, Liesa is working to develop new vaccines that prevent infectious diseases caused by bacteria. Outside of work, Liesa loves spending time at home with her husband, sixteen year old son, twelve year old daughter, and the family’s new dog. She also enjoys being outside, visiting the Jersey Shore beaches, taking exercise classes with her husband, and serving as a girl scout leader. She earned her PhD in Biological Sciences from the University of Warwick in the UK. Afterwards, Liesa was awarded a Natural Environment Research Council postdoctoral fellowship which she completed at the University of Coventry. She was subsequently awarded a Royal Society postdoctoral fellowship during which she conducted research at the University of Warwick. Next, Liesa worked for about 9 years at Merck Research Laboratories. She then joined the team at Wyeth a few years before it was acquired by Pfizer, and she has been with Pfizer ever since. Liesa is a Member of the Microbiology Society, a Fellow of the American Academy for Microbiology, a Fellow of the Royal Society of Medicine, and she serves on the Microbiology and Infectious Disease Steering Committee at the NY Academy of Sciences. In our interview Annaliesa will share more about her life and science.
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Apr 22, 2019 • 41min

498: Researching Novel Methods to Regenerate Functionally-Polarized Tissues - Dr. Denver Lough

Dr. Denver Lough is President, Chief Executive Officer, and Chairman of PolarityTE, a biotech company developing methods for patients’ own cells to regenerate functionally-polarized tissues. Denver and the team at Polarity TE have developed novel methods to successfully induce regeneration across the full spectrum of tissue types including skin, muscle, and bone. They have accomplished this by understanding the environment, stimuli, and interactions needed for these tissues to orient, self-organize, and develop. With their technology, patients with a variety of diseases and injuries can regenerate fully functional tissues from their own cells. When he isn’t working at PolarityTE, Denver enjoys spending time with his wife and three young children. It is exciting to watch them learn and discover new things about the world, and it makes Denver appreciate all the incredible things in life that we sometimes overlook. Denver received his MD and PhD in Biochemistry and Molecular and Cell Biology from Georgetown University. He completed his residency in Plastic Surgery at Johns Hopkins University. Afterwards, Denver founded PolarityTE. In our interview Denver will tell us more about his life and science.

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