People Behind the Science Podcast Stories from Scientists about Science, Life, Research, and Science Careers

Dr. Marie McNeely, featuring top scientists speaking about their life and c
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May 18, 2020 • 42min

554: Using Rehabilitation Robotics and Noninvasive Brain Stimulation to Promote Recovery After Brain Injury - Dr. Dylan Edwards

Dr. Dylan Edwards is Director of the Moss Rehabilitation Research Institute as well as an Institute Scientist and Director of the Human Motor Recovery Laboratory there. In addition, he is Professor of Neuroscience at Edith Cowan University in Australia, and Faculty at Harvard Medical Schools Continuing medical education program in Transcranial Magnetic Stimulation. In his research, Dylan studies the recovery of movement following damage to the nervous system that may occur after stroke or spinal cord injury. He and his team use rehabilitation robots to assess and train motor function. They also apply noninvasive stimulation to test the circuitry of the nervous system and as an experimental treatment to augment function. When he's not at work, you can find Dylan hanging out with his family, enjoying fantastic food, playing the guitar, observing nature, traveling, and thinking about the future of technology and human civilization. He stays active through running and hitting the waves at his favorite surfing destinations around the world. Dylan received a B.App.Sci. degree with a focus in exercise physiology from Edith Cowan University in Australia and a B.S. degree in Physical Therapy from Curtin University of Technology in Australia. He was awarded his PhD in clinical neurophysiology at the Centre for Neuromuscular and Neurological Disorders at the University of Western Australia (now the Perron Institute for Neurological and Translational Sciences), and he conducted postdoctoral research there afterwards. Prior to joining the team at MRRI, Dylan served as Director of the Non-Invasive Brain Stimulation Laboratory at Burke Neurological Institute, and was Associate Professor of Clinical Neurophysiology at Weill Cornell Medicine in New York.
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May 11, 2020 • 40min

553: Examining the Impacts of Exercise on Cardiovascular Health After Stroke - Dr. Ada Tang

Dr. Ada Tang is a physical therapist, an Associate Professor in the School of Rehabilitation Science at McMaster University, and a Clinician-Scientist with the Ontario Heart and Stroke Foundation. We know that exercise is an important part of healthy living for everyone, but it can be more difficult for people with stroke to exercise as a result of mobility problems and other factors. Unfortunately, exercise is typically not a strong focus in stroke rehabilitation. Ada and her research team are assessing the impacts of exercise on the cardiovascular health of people with stroke, as well as other populations, and they are working to develop safe and effective exercise programs for people with stroke. Sport and exercise have always been important in Ada's life. In addition to studying exercise in the lab, Ada loves being active outdoors. She spends her free time hiking, enjoying nature, and traveling. Ada is also an avid sports fan, and she enjoys watching sporting events, particularly basketball games with the Toronto Raptors. Ada completed her BSc in Physical Therapy, MSc in Rehabilitation Science, and PhD in Medical Science from the University of Toronto. Afterwards, she was awarded a Canadian Institutes of Health Research Fellowship and conducted postdoctoral research at the University of British Columbia before joining the faculty at McMaster University. In our interview, Ada shares more about her life and science.
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May 4, 2020 • 41min

552: Making a Mechatronic Tremor Suppression Glove for People with Parkinson's Disease - Dr. Ana Luisa Trejos

Dr. Ana Luisa Trejos is an Associate Professor of Electrical and Computer Engineering as well as Biomedical Engineering at Western University in Canada. She is also an Associate Scientist at the Lawson Health Research Institute. Ana Luisa's research is in the area of mechatronic systems engineering. This field combines mechanical, electrical, computer, and software engineering to develop smart machines that can perceive what is happening in the environment and react intelligently. In particular, she is designing wearable mechatronic technologies that can help people recover from mobility problems due to a musculoskeletal injury or a movement disorder like Parkinson's disease. Her goal is to make these technology solutions more comfortable for users and to restore mobility and quality of life for people with upper body movement impairments. When she's not at work, Ana Luisa enjoys hanging out with her family, reading, putting together jigsaw puzzles, hiking, swimming, running, and renovating her house. Ana Luisa was awarded her B.Sc. degree in mechanical engineering from the University of Costa Rica and her M.A.Sc. in mechanical engineering from the University of British Columbia. She worked as an Applications Engineer for Progressive Moulded Products in Ontario from 2000-2003. She then joined the team at Canadian Surgical Technologies & Advanced Robotics at Western University as a research engineer. Ana Luisa later attended graduate school at Western University where she was awarded her Ph.D. degree in electrical and computer engineering in 2012. Ana Luisa has been awarded the IEEE London Section Outstanding Women in Engineering Award and the For Inspiration and Recognition of Science and Technology (FIRST) Canada District Volunteer Appreciation Award. In our interview, Ana Luisa shares more about her life and research.
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Apr 27, 2020 • 41min

551: Applying Insights from Human Genetics to Create New Cancer Therapies - Dr. Tim Behrens

Dr. Tim Behrens is Senior Vice President of Human Genetics at the biotech company Maze Therapeutics and Adjunct Professor of Medicine in Rheumatology at the Medical College of Wisconsin. In his research, Tim is working to apply lessons and insights from human genetics to develop new drugs for different diseases. For example, Tim and the team at Maze Therapeutics are working on developing a drug that activates the immune system in new ways to fight cancer. Tim is an avid outdoors enthusiast, so he loves spending his free time canoeing, fishing, and going on wilderness trips. He also enjoys spending time playing the guitar, hanging out with his wife and two children, and playing fetch with the family dogs. Tim received his B.S. in biology from the University of Illinois at Urbana-Champaign and his M.D. from Southern Illinois University School of Medicine. He completed his residency in Internal Medicine and a fellowship in Rheumatology/Immunology at the Medical College of Wisconsin. Afterwards, Tim worked as an emergency room physician at Brookfield Memorial Hospital in Wisconsin for about a year before accepting a postdoctoral fellowship at the National Cancer Institute of the National Institutes of Health. Tim joined the faculty at the University of Minnesota Medical School in 1992, and he worked there until 2006 when he accepted the position of Senior Director and Head of the Department of Human Genetics at Genentech, Inc. After over a decade at Genentech, Tim became an independent consultant and later accepted his current position at Maze Therapeutics.Tim has received numerous awards and honors over the course of his career, including recognition for one of the Top 10 Advances in Rheumatology in 2003 and 2004 by the Arthritis Foundation, being named the John F. Finn Arthritis Foundation Land Grant Endowed Chair at the University of Minnesota Medical School, as well as receipt of the Edmund L. Dubois Memorial Award for Research in Lupus from the American College of Rheumatology, the Leukemia & Lymphoma Society Scholar Award, the Feltl Family Award for Research in Rheumatic Disease, and other honors. In our interview, Tim shares more about his life and science.
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Apr 20, 2020 • 55min

550: Developing Novel Drugs to Treat Autoimmune Disease and Inflammation - Dr. Paul Changelian

Dr. Paul Changelian is Vice President of Biology at Aclaris Therapeutics and Director of Biology at Confluence Life Sciences. He is working to discover new drugs to treat autoimmune disease and inflammation in conditions like rheumatoid arthritis, ulcerative colitis, Crohn's disease, and multiple sclerosis. In these conditions, the immune system inadvertently attacks cells in your body. He and his team are working to identify and test small molecule drugs that patients could take by pill that would inhibit this abnormal activation of the immune system to slow down damage to joints or other areas that may be under attack. They have also recently begun working on potential cancer treatments that can impact inflammation around tumors to improve the body's ability to clear tumors. Some of Paul's passions outside of science include exercising, walking around in nature, and music. He listens to hard rock and jazz music, and he enjoys playing jazz music on the trumpet. Paul received his B.S. in chemistry from the University of Michigan in Ann Arbor and his Ph.D. in immunology from Harvard University in Cambridge. Afterwards, he conducted postdoctoral research in neurobiology at Washington University in St. Louis. Paul then worked in various roles at Pfizer for about 18 years. He served briefly on the faculty at the University of Michigan in Ann Arbor before becoming Director of Biology at Lycera Corporation. From 2012 - 2014, Paul served as Senior Director of Pharmacology at Infinity Pharmaceuticals before accepting his current positions.
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Apr 13, 2020 • 44min

549: Unearthing Clues to Reveal How People Lived in Early Mesoamerican Cities - Dr. Verónica Pérez Rodríguez

Dr. Verónica Pérez Rodríguez is an Associate Professor of Anthropology at the University at Albany, State University of New York (SUNY). Verónica is an archaeologist and anthropologist who is interested in studying people and life in cities over time. Through her work, she examines how people lived many years ago, what brought them to cities, what made them stay, what were the tradeoffs, and what were the environmental impacts. Her work focuses on the highlands of the Mixteca Alta in the southern Mexican state of Oaxaca. This region was a cradle of urbanism, innovation, and complex societies as early as 300 BC. When she's not working, Verónica loves relaxing at home, watching movies, and hiking with her children and her husband. She also loves running outdoors, knitting, and reading fiction books in her free time. She earned a B.A. in Anthropology as well as a B.A. in Linguistics from the University of Texas at El Paso. Verónica then attended graduate school at the University of Georgia where she was awarded her Ph.D. in Ecological and Environmental Anthropology. She served on the faculty at Northern Arizona University before joining the faculty at the University at Albany, SUNY in 2013. In our interview, Verónica shares more about her life and science.
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7 snips
Apr 6, 2020 • 47min

548: Studying New Cellular Mechanisms of Memory Involving Myelin - Dr. Douglas Fields

Dr. R. Douglas Fields, Chief of the Nervous System Development and Plasticity Section at the NIH, dives deep into the fascinating world of neuroscience. He discusses how myelin actively contributes to memory and learning, reshaping our understanding of the brain. The conversation also explores the challenges and joys of scientific discovery, including failures and innovative funding approaches. Beyond research, Doug shares his passion for guitar building and the delightful craft of brewing, illustrating the artistic side of science.
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Mar 30, 2020 • 36min

547: Examining Episodic Memory and Making Sense of Memory Failures - Dr. Ayanna Thomas

Dr. Ayanna Thomas is Professor of Psychology and Director of the Graduate Program in Psychology at Tufts University. Ayanna conducts research to answer a wide variety of questions related to memory. She aims to better understand how our memories work, how our memories fail, how we perceive our memory function (metacognition), how memories change over time, and what are the impacts and implications of these aspects of memory for our everyday lives. In her free time, Ayanna loves watching movies. She and her husband have a tradition where they watch a different horror movie every night throughout the month of October to celebrate Halloween. Ayanna was awarded her B.A. in psychology from Wesleyan University and her Ph.D. in cognitive psychology from the University of Washington. Afterwards, Ayanna conducted postdoctoral research at Washington University in St. Louis. She worked as an Assistant Professor at Colby College before joining the faculty at Tufts in 2007. In our interview, Ayanna tells us more about her life and science.
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Mar 23, 2020 • 51min

546: Investigating the Impacts of Geochemistry and Nanoscale Materials on our Planet - Dr. Michael Hochella

Dr. Michael Hochella is a University Distinguished Professor Emeritus at Virginia Tech. Michael's research is at the intersection of nanoscience and environmental geochemistry. He studies very small things that can impact the health of the planet and the health of humans. Since childhood, Mike has been fascinated by airplanes and flying, and he received his pilot's license as an undergraduate student. Over 45 years later, Mike still delights in seeing Earth from the pilot's seat thousands of feet above ground. He received his B.S. and M.S. degrees in Geological Sciences from Virginia Tech, and was awarded his Ph.D. in Earth Sciences from Stanford University. Michael served on the faculty at Stanford University before joining the faculty at Virginia Tech. He has been the recipient of many awards and honors throughout his career. Michael is an elected Fellow of the Geological Society of America, the Mineralogical Society of America, the American Geophysical Union, the European Association of Geochemistry, the Geochemical Society, the American Association for the Advancement of Science, the International Association of GeoChemistry, the Royal Society of Chemistry, and Pacific Northwest National Laboratory. He has also been awarded a Senior Fulbright Scholar Award, an Alexander von Humboldt Award, the Dana Medal of the Mineralogical Society of America, the Department of Energy Outstanding Research Award for Geosciences, the Virginia Tech Alumni Award for Research Excellence, the Virginia Scientist of the Year Award, the Distinguished Service Medal from The Geochemical Society, the George W. Brindley Lecture Award from the Clay Minerals Society, and most recently the Virginia Outstanding Faculty award in 2016. In addition, Michael is a former President of both the Geochemical Society, as well as the Mineralogical Society of America. In our interview, Michael shares more about his life and science.
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Mar 16, 2020 • 46min

545: Applying CRISPR Technologies to Advance Food Science, Health, and Sustainability - Dr. Rodolphe Barrangou

Dr. Rodolphe Barrangou is the Todd R. Klaenhammer Distinguished Professor in the Department of Food, Bioprocessing and Nutrition Sciences at North Carolina State University. He is also Editor-In-Chief of The CRISPR Journal and co-founder of Intellia Therapeutics, Locus Biosciences and TreeCo. Rodolphe's research is focused on CRISPR gene editing technologies that allow us to modify the DNA in organisms ranging from bacteria to trees to humans. His lab primarily works to study and apply CRISPR technologies in bacteria to make food healthier, promote beneficial gut microbes, and help us be healthier. When he's not working, Rodolphe enjoys spending time with his wife and three teenage children. He typically wakes up early and gets energized to greet each day with high intensity cardiovascular exercise as well as yoga. Rodolphe received his B.S. degree in biological sciences from Rene Descartes University in France, a M.S. in biological engineering from the University of Technology in Compiegne in France, a M.S. in food science from North Carolina State University, and his Ph.D. in functional genomics from North Carolina State University. He worked as an R&D Director at Danisco (a company now affiliated with DuPont) before returning to school to earn his MBA in Executive Business Administration from the University of Wisconsin-Madison. He has received numerous awards and honors for his research, including the National Academy of Sciences Prize in Food and Agriculture Sciences, the Award in Molecular Biology from the National Academy of Sciences, the Warren Alpert Foundation Prize, and the Canada Gairdner International Prize. In addition, Rodolphe is an Elected Member of the National Academy of Sciences, the National Academy of Engineering and the National Academy of Inventors. In our interview, Rodolphe shares more about his life and science.

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