Clear+Vivid with Alan Alda

Mario Livio, an astrophysicist who dedicated 24 years to the Hubble Space Telescope, dives into the thrilling implications of recent discoveries that may signal life beyond Earth. He passionately discusses the idea that our galaxy could be teeming with life and explores the complexities of identifying biosignatures on distant planets. Livio also addresses the challenges of intelligent life, the skepticism surrounding colonizing Mars, and the intersection of AI and consciousness. His insights encourage a deeper curiosity about our universe and humanity's future.

Colman Domingo, a celebrated actor, playwright, and producer known for his roles in Rustin and The Four Seasons, shares his inspiring journey in this conversation. He highlights the transformative power of theater programs in prisons, discussing how art can promote rehabilitation. Domingo also uncovers the legacy of Bayard Rustin, emphasizing the need to recognize hidden figures in civil rights history. Additionally, he reflects on the importance of authentic connections in performance, blending preparation with emotion to create impactful art.

Eric Topol, a physician and expert in genomics and digital medicine, discusses revolutionary insights into aging and health. He emphasizes the importance of enhancing life quality over mere longevity through lifestyle changes he calls 'Lifestyle+'. Topol explores exciting advancements in early disease detection and draws parallels between dog aging studies and human health. He also highlights challenges in funding for biomedical research that could impact crucial clinical trials and vaccine communication efforts.

AI generated voices like Alexa and Siri are now so much a part of our everyday experience that disembodied chatbots that talk are edging ever closer to being accepted as real. And not for the first time: attempts to generate artificial human voices date back over two centuries.

Carl Zimmer, an award-winning science writer and New York Times columnist, dives into the invisible life thriving in our air and its overlooked significance during the COVID-19 pandemic. He discusses the historical misconceptions about airborne pathogens and highlights key research from the 1930s that shaped our understanding today. Zimmer further elaborates on the use of UV light for disinfection during airborne disease outbreaks and emphasizes the critical need for clear scientific communication and historical context in public health.

John Leguizamo, a dynamic actor, writer, and producer celebrated for his roles in 'Ice Age' and 'The Untold History of Latinos in the US,' shares his insights on creativity and Latino representation. He reflects on the spontaneity of performance and the deep emotional roots of his new film, 'Bob Trevino Likes It.' The conversation humorously touches on chaotic experiences in transitioning to Broadway and discusses the importance of recognizing Latino contributions in Hollywood and American culture. His anecdotes emphasize the significance of communication and family legacy.

Carl Zimmer, a renowned science writer and author who specializes in biology and evolution, delves into the fascinating world of airborne life and disease transmission. He discusses insights from his book 'Airborne,' shedding light on how airborne pathogens impact us and drawing connections to historical expeditions like the Lindberghs'. Zimmer also emphasizes the urgency of understanding modern virus transmission, especially in light of recent global health challenges.

Bill Pullman, celebrated actor known for his roles in Independence Day and The Sinner, opens up about his remarkable journey after surviving a near-fatal stage fall. He shares insights on transitioning from theater to screen, emphasizing the fusion of art and science in his projects. Bill discusses the emotional nuances of character development and the significance of impactful direction in filmmaking. Plus, he reflects on how near-death experiences shifted his perspective on life, and how he's now venturing into science communication while making cider for his community.

Alison Wood Brooks, a Harvard Business School professor and author of "Talk: The Science of Conversation and the Art of Being Ourselves," dives into the complexities of communication. She introduces the powerful acronym TALK, highlighting the significance of Topic, Questions, Levity, and Kindness in fostering meaningful connections. The conversation covers practical strategies for engaging children in dialogue, reframing anxiety into excitement, and the art of concluding conversations with empathy. Brooks shares anecdotes that illuminate the intricate dance of effective communication.

A psychiatrist, engineer and neuroscientist, Kaf Dzirasa is researching ways to reengineer the brain to make it better able to cope with stress and so improve mental health.