eanCast: Weekly Neurology

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May 18, 2025 • 21min

Ep. 148: Ultrasound-Guided Botulinum Toxin Injection in Dystonia

Moderator: Nihat Mustafayev (Istanbul, Türkiye) Guest: Dr Anna Castagna (Milano, Italy) This episode explains how ultrasound-guided botulinum toxin injections are performed in patients with dystonia. Mustafayev and Castagna discuss who benefits most fr Moderator: Nihat Mustafayev (Istanbul, Türkiye)Guest: Dr Anna Castagna (Milano, Italy) This episode explains how ultrasound-guided botulinum toxin injections are performed in patients with dystonia. Mustafayev and Castagna discuss who benefits most from this method and why it is considered a safe and effective approach in clinical practice.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely already an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password’-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.
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May 11, 2025 • 31min

Ep. 147: Basic Immunology in Rare CNS Disorders

Moderator: Gianmarco Abbadessa (Naples, Italy) Guest: Heinz Wiendl (Muenster, Germany) In this episode, Abbadessa and Wiendl delve into the pathogenesis and pathophysiology of rare CNS autoimmune disorders, examining the intricate immune mechanisms that Moderator: Gianmarco Abbadessa (Naples, Italy)Guest: Heinz Wiendl (Muenster, Germany)Moderator: Gianmarco Abbadessa (Naples, Italy)Guest: Heinz Wiendl (Muenster, Germany)In this episode, Abbadessa and Wiendl delve into the pathogenesis and pathophysiology of rare CNS autoimmune disorders, examining the intricate immune mechanisms that underpin these conditions. Wiendl emphasized the crucial role that a deeper understanding of these processes plays in shaping therapeutic strategies. They explored the distinctive features of disorders such as NMO, MOGAD, autoimmune encephalitis, and immune checkpoint inhibitor-associated neurological diseases, discussing how these differences guide the selection of targeted treatments.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely already an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password’-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.
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May 4, 2025 • 28min

Ep. 146: Importance of brain donation in neurodegenerative diseases

Ean Moderator: Yıldız Değirmenci (Istanbul, Türkiye) Guest: Didem Öz (Izmir, Türkiye) In this episode, Değirmenci and Öz discuss the vital importance of brain donation in understanding and treating neurodegenerative diseases. They also highlight the Tu Ean Moderator: Yıldız Değirmenci (Istanbul, Türkiye)Guest: Didem Öz (Izmir,  Türkiye)In this episode, Değirmenci and Öz discuss the vital importance of brain donation in understanding and treating neurodegenerative diseases. They also highlight the Turquoise Outreach Project—a meaningful initiative that builds bridges between the community and dementia research, promoting awareness, inclusion, and progress.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely already an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password’-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.
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Apr 27, 2025 • 20min

Ep. 145: Why Should Neurologists Care About the World Dance Day?

Moderator: Alicia Gonzalez Martinez (Madrid, Spain) Guests: Thomas Berger (Vienna, Austria), Julia Polai (Innsbruck, Austria) In this episode for World Dance Day, Gonzales Martinez discusses the physical, emotional, and neurological benefits of dancing w Moderator: Alicia Gonzalez Martinez (Madrid, Spain)Guests: Thomas Berger (Vienna, Austria), Julia Polai (Innsbruck, Austria)In this episode for World Dance Day, Gonzales Martinez discusses the physical, emotional, and neurological benefits of dancing with neurologist Berger, and dancer and patient Polai. They emphasize its therapeutic potential for people with neurological conditions and highlight how dance engages multiple brain functions and fosters social connection, making it a valuable tool for both patients and healthcare professionals.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely already an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password’-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.
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Apr 20, 2025 • 19min

Ep. 144: New Methods to Identify Larger Structural Variants

Moderator: Maria Judit Molnar (Budapest, Hungary) Guest: Arianna Tucci (London, UK) In this episode Molnar hosts Tucci as they explore how advancements in short- and long-read sequencing technologies are revolutionizing the diagnosis of neurogenetic diso Moderator: Maria Judit Molnar (Budapest, Hungary)Guest: Arianna Tucci (London, UK)In this episode Molnar hosts Tucci as they explore how advancements in short- and long-read sequencing technologies are revolutionizing the diagnosis of neurogenetic disorders by uncovering genetic variants previously missed by traditional methods.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely already an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password’-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.
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Apr 13, 2025 • 22min

Ep. 143: Novel Aspects of Repeat Expansions in Disease

Moderator: Francesca Magrinelli (London, UK)Guest: Andrea Cortese (London, UK)Join Magrinelli as she interviews Cortese about recent developments in the diagnosis and management of repeat expansion disorders, including diseases caused by repeats in non-coding genomic regions.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely aleady an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password’-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.
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Apr 6, 2025 • 30min

Ep. 142: Papers of the Month: Mismatch Repair & DNA Expansion in Huntington’s Disease

Moderator: Jean-Marc Burgunder (Guemligen, Switzerland)Guest: Sandrine Humbert (Paris, France)In this week's episode, Burgunder and Humbert discuss the intriguing phenomenon of somatic expansion—the further increase of CAG repeat numbers in the gene involved in Huntington’s disease, particularly in the striatum. They explore the molecular mechanisms behind this process, as addressed in two recent research papers.Please find here the papers discussed in this episode: Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s diseaseand Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely aleady an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password’-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.
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Mar 30, 2025 • 19min

Ep. 141: Sodium Valproate in Men

EAN moderator: Barbara Tettenborn (St. Gallen, Switzerland) Guest: Tony Marson (Liverpool, UK) In this special episode, Tettenborn and Marson discuss sodium valproate treatment for epilepsy, focusing on its use in men. They try to deemphasize the potenti EAN moderator: Barbara Tettenborn (St. Gallen, Switzerland)Guest: Tony Marson (Liverpool, UK)In this special episode, Tettenborn and Marson discuss sodium valproate treatment for epilepsy, focusing on its use in men. They try to deemphasize the potential risks of reduced fertility and the lately published potential neurodevelopmental effects on children born to men taking the drug, while also addressing the challenges in balancing treatment effectiveness and safety.
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Mar 23, 2025 • 20min

Ep. 140: Transition from Childhood to Adulthood​

Moderator: Gudrun Gröppel​ (Linz, Austria) Guests: Dana Craiu​ (Bucharest, Romania), Thomas Berger​ (Vienna, Austria) This episode explores the challenges and solutions in transitioning young neurology patients from pediatric to adult care. Gröppel, Cra Moderator: Gudrun Gröppel​ (Linz, Austria)Guests: Dana Craiu​ (Bucharest, Romania), Thomas Berger​ (Vienna, Austria)This episode explores the challenges and solutions in transitioning young neurology patients from pediatric to adult care. Gröppel, Craiu and Berger discuss the importance of patient education, parental involvement, and collaborative efforts between pediatric and adult neurologists to ensure a smooth transition.If you want to participate in the mentioned survey, please see here: Transition from child to adult care in Pediatric Neurological Disorders in Europe – a joint EAN-EPNS Survey (available until 28 March 2025, 23:59).
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Mar 16, 2025 • 24min

Ep. 139: Supporting Early Brain Development

Moderator: Leena Haataja (Helsinki, Finland) Guests: Silja Kosola (Helsinki, Finland), Liisa Lehtonen (Turku, Finland) In the third March episode Haataja, Kosola and Lehtonen focus on evidence-based antenatal and neonatal care practices to protect the b Moderator: Leena Haataja (Helsinki, Finland)Guests: Silja Kosola (Helsinki, Finland), Liisa Lehtonen (Turku, Finland)In the third March episode Haataja, Kosola and Lehtonen focus on evidence-based antenatal and neonatal care practices to protect the brains and later outcomes of newborn infants. Furthermore, the phenomena and effects of excessive internet use, sleep deprivation and loneliness among school aged children and adolescents are discussed.

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