eanCast: Weekly Neurology

eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely already an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password’-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.

Moderator: Francesca Magrinelli (London, UK)Guest: Andrea Cortese (London, UK)Join Magrinelli as she interviews Cortese about recent developments in the diagnosis and management of repeat expansion disorders, including diseases caused by repeats in non-coding genomic regions.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely aleady an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password’-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.

Moderator: Jean-Marc Burgunder (Guemligen, Switzerland)Guest: Sandrine Humbert (Paris, France)In this week's episode, Burgunder and Humbert discuss the intriguing phenomenon of somatic expansion—the further increase of CAG repeat numbers in the gene involved in Huntington’s disease, particularly in the striatum. They explore the molecular mechanisms behind this process, as addressed in two recent research papers.Please find here the papers discussed in this episode: Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s diseaseand Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely aleady an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password’-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.

EAN moderator: Barbara Tettenborn (St. Gallen, Switzerland)Guest: Tony Marson (Liverpool, UK)In this special episode, Tettenborn and Marson discuss sodium valproate treatment for epilepsy, focusing on its use in men. They try to deemphasize the potential risks of reduced fertility and the lately published potential neurodevelopmental effects on children born to men taking the drug, while also addressing the challenges in balancing treatment effectiveness and safety.

Moderator: Gudrun Gröppel​ (Linz, Austria)Guests: Dana Craiu​ (Bucharest, Romania), Thomas Berger​ (Vienna, Austria)This episode explores the challenges and solutions in transitioning young neurology patients from pediatric to adult care. Gröppel, Craiu and Berger discuss the importance of patient education, parental involvement, and collaborative efforts between pediatric and adult neurologists to ensure a smooth transition.If you want to participate in the mentioned survey, please see here: Transition from child to adult care in Pediatric Neurological Disorders in Europe – a joint EAN-EPNS Survey (available until 28 March 2025, 23:59).

Moderator: Leena Haataja (Helsinki, Finland)Guests: Silja Kosola (Helsinki, Finland), Liisa Lehtonen (Turku, Finland)In the third March episode Haataja, Kosola and Lehtonen focus on evidence-based antenatal and neonatal care practices to protect the brains and later outcomes of newborn infants. Furthermore, the phenomena and effects of excessive internet use, sleep deprivation and loneliness among school aged children and adolescents are discussed.

Moderator: Elena Moro (Grenoble, France)Guest: Paul Boon​ (Gent, Belgium)This special episode of eanCast explores the Brain Health Roadmap Paper initiated by the European Academy of Neurology, highlighting its goals to advance brain health through research, education, policy initiatives, and public awareness. Prof. Moro (EAN President) and lead author, Prof. Boon (EAN Past President & BHM Co-Chair) discuss the urgent need for preventive measures, multidisciplinary collaboration, and the integration of brain health into neurology education and healthcare systems across Europe.For more information on the Brain Health Mission, please visit Brain Health Mission - ean.org. If you are interested to learn about the School Challenge mentioned in the episode, check it out here: Join the Brain Health School Challenge! - ean.org.

Moderator: Justyna Paprocka (Katowice, Poland)Guests: Laurent Servais (Oxford, UK), Michelangelo Mancuso (Pisa, Italy)In this first March episode, Paprocka, Mancuso, and Servais explore groundbreaking advancements in treating rare neurological disorders, focusing on paediatric and adolescent neurology. They discuss the role of gene therapy, emerging treatment strategies for neuromuscular disorders, and the evolving challenges of transitioning care from paediatric to adult neurology.

Moderator: Andreu Vilaseca (Rochester, USA)Guest: Barbara Willekens (Edegem, Belgium) and Ilka Kleffner (Bochum, Germany)For the last February episode join Vilaseca, Willekens and Kleffner as they explore the complexities of Susac syndrome, a rare neuroimmunological disorder, through insightful case discussions and expert opinions. They discuss its diagnosis, pathophysiology, and the latest approaches to treatment.

Moderator: Yıldız Değirmenci (Istanbul, Türkiye)Guest: Natalia Szejko (Warsaw, Poland)In this episode Yıldız Değirmenci interviews Natalia Szejko about the controversial topic of cannabis-based medicine (CBM) in neurology.Değirmenci and Szejko raise awareness and resolve some important misconceptions, as questions about CBM are frequently asked by patients.