eanCast: Weekly Neurology

Moderator: Justyna Paprocka (Katowice, Poland) Guests: Stephan Rüegg (Basel, Switzerland), Markus Leitinger (Salzburg, Austria) In this episode, Justyna Paprocka welcomes Stefan Rüegg and Markus Leitinger to examine how clinicians can approach emergency EEG in suspected non-convulsive status epilepticus (NCSE). They discuss NCSE epidemiology, the importance of continuous EEG, and the use of structured diagnostic frameworks including the Salzburg criteria and the 2HELPS2B score. The conversation highlights practical strategies such as IV anti-seizure medication trials, pitfalls in benzodiazepine use, and the complexities of distinguishing NCSE from encephalopathy. The experts also address EEG interpretation in post-anoxic patients and recommend foundational literature for early-career neurologists.

Moderator: Messud Ashina (Copenhagen, Denmark) Guests: Theodoros Mavridis (Dublin, Ireland), Oxana Grosu (Chișinău, Moldova) In this episode, Messud Ashina is joined by Theodoros Mavridis and Oxana Grosu to discuss the latest advances in pain and headache medicine, as highlighted in the EAN Pain and Headache Panels' Yearbook chapters. The conversation dives into recent breakthroughs in the pathophysiology of pain and headaches, as well as cutting-edge approaches to prevention and treatment. The experts explore how new research is influencing clinical practice, with a focus on the synergies between pain and headache management. They also examine emerging trends, potential future directions, and the impact of these developments on patient care.

Moderator: Theodoros Mavridis (Dublin, Ireland) Guests: Diana Aguiar de Sousa (Lisbon, Portugal), Mira Katan (Basel, Switzerland) Embolic stroke of undetermined source (ESUS) continues to challenge clinicians as its definition and diagnostic approach evolve. In this episode, Theodoros Mavridis is joined by Diana Aguiar de Sousa and Mira Katan. They explore the epidemiological, clinical and mechanistic nuances of ESUS, discuss insights gained from major clinical trials, and examine current therapeutic strategies. The conversation also highlights advances in detecting covert embolic sources, the emerging relevance of atrial myopathy, the role of PFO closure, and the promise of biomarkers in shaping future patient care.

Theodoros Mavridis (Dublin, Ireland) Ana Catarina Fonseca (Lisbon, Portugal) In this episode, Theodoros Mavridis speaks with Ana Catarina Fonseca about the updated European guidelines for acute ischemic stroke. They discuss advances in reperfusion therapy, including extended time windows for thrombolysis using advanced imaging, broader eligibility criteria, and evidence supporting thrombectomy in patients with low ASPECTS scores, mild deficits, and posterior circulation strokes. The conversation also highlights the continued importance of stroke unit care and emerging pre-hospital technologies aimed at speeding diagnosis and improving outcomes.

Moderator: Theodoros Mavridis (Dublin, Ireland) Guest: David Seiffge (Bern, Switzerland) In this episode, Theodoros Mavridis speaks with guest David Seiffge about breakthrough strokes, a challenging condition where ischemic strokes occur despite the use of antithrombotic therapies. They explore the diagnostic process, investigating compliance, and identifying competing etiologies. Prof. Seiffge also discusses potential treatment options, including emerging therapies like Factor 11 inhibitors and left atrial appendage closure, offering insights into ongoing trials aimed at improving patient outcomes.

Moderator: Benedetta Storti (San Donà di Piave, Italy) Guest: Charlotte Cordonnier (Lille, France) Join Benedetta Storti and Charlotte Cordonnier for a discussion on the acute management of intracerebral hemorrhage. Discover the latest European Stroke Organization guidelines, the importance of timely intervention, and the evolving role of reversal agents and surgical approaches in stroke care.

Moderator: Mathilde Leonardi (Milan, Italy) Guests: Sanja Gluscevic (Podgorica, Montenegro), Simone Salemme (Modena, Italy) This episode explores how early-career neurologists can bridge science, policy, and society through advocacy—highlighting real examples of how EAN Brain Health Ambassadors are translating brain health into action both within and beyond clinical practice. Becoming a certified Brain Health Ambassador through the EAN's Advocacy Training programme offers neurologists the chance to advance brain health by gaining the knowledge and practical skills needed to advocate effectively at local, national, and European levels. As part of the training, participants will explore the principles of effective advocacy, develop communication strategies, and learn how to engage with key stakeholders such as policymakers and patient organizations in order to drive positive change. Applications for the third class of EAN Advocacy Training are now open, with the deadline for submissions set for 30 November 2025.

Moderator: Alice Accorroni (Geneva, Switzerland) Guests: James Teo (London, UK), Giuseppe Jurman (Trento, Italy) In this special episode, Dr Alice Accorroni is joined by Professor James Teo and Professor Giuseppe Jurman to discuss the impact of artificial intelligence in neurology: They analyse the actual improvements provided by its adoption, the factors that are hindering this same adoption, especially in a clinical setting, the potential future landscape clinicians and data scientists will be facing and how neurologists' attitude can be oriented more favourably towards new AI solutions. The Task Force on Artificial Intelligence in Clinical Neurology is cordially inviting listeners to take our survey: Artificial Intelligence in Clinical Neurology Survey.

Moderator: Raphael Wurm (Vienna, Austria) Guest: Francisco Cardoso (Belo Horizonte, Brasil) Artificial intelligence - hype or revolution? For this week’s special episode, Dr Raphael Wurm welcomes Prof. Cardoso, a movement disorder expert and busy clinician, to explain why he believes that human interaction and connection will remain the most important part of our profession. The Task Force on Artifical Intelligence in Clinical Neurology is cordially inviting listeners to take our survey: Artificial Intelligence in Clinical Neurology Survey

Join us as Dr Roberta Balestrino and Professor Nathalie Nasr takes us on a journey into the brain in space—uncovering the vascular challenges of microgravity, their impact on astronauts, and surprising lessons for our health here on Earth.