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New Books in Biology and Evolution

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Apr 30, 2024 • 1h 11min

Christian Hansel, "Memory Makes the Brain: The Biological Machinery That Uses Experiences To Shape Individual Brains" (World Scientific, 2021)

If you're interested in memory, you'll find a lot in Memory Makes the Brain: The Biological Machinery That Uses Experiences To Shape Individual Brains (World Scientific, 2021), from cellular processes to unique and interesting perspectives on autism. Detailed descriptions of cellular processes involved in forming a memory. Connecting those cellular processes to everyday experiences - like the memorable image of a butterfly seen during a hike decades ago. Comparisons of plasticity in different brain areas, like cortex, hippocampus, cerebellum. Comparisons of plasticity and learning in different phases of the human life. Important milestones in the history of neuroscience. Like Wiesel and Hubel's work identifying the critical period for plasticity, or Huttenlocher's discovery of synaptic pruning. Up-to-date science and open questions about autism, a wide range of phenomena that seems to be connected both to synaptic pruning and to the funtion of the cerebellum. An outlook on non-synaptic plasticity. Professor Christian Hansel starts both the book and the conversation with establishing a very broad definition of memory. Traditionally, a lot of research focused on the "observable outcome" of learning: acquiring new skills, changing behavior. Instead, he defines memory as any event that changes the brain.The first 2 chapters introduce major discoveries from the 1960s and 1970s. David Hubel and Thorsten Wiesel examined the visual system of kittens. They recognized that it's much more adaptive in a "critical period", ca. 4-8 weeks after birth. Peter Huttenlocher discovered another fascinating phenomena during childhood: synaptic pruning. In the years 2-12, a lot of synapses (connections between neurons) disappear.Chapter 3 describes the molecular machinery behind all these observations. We'll get to know the terms LTP (long-term potentiation) and LTD (long-term depression), which mean the long-term strengthening and weakening of synaptic connections respectively. We find a detailed description of these processes, incl. the enzymes, neurotransmitters and receptors contributing to them.Chapter 4 continues examining these processes across the human life span. The (perhaps surprising) conclusion: The machinery for synaptic plasticity is quite similar in a small child an in an adult. What's different is the magnitude of these processes.Autism is a central topic both in the book and in the Hansel Lab's work. Chapter 5 starts with describing the difficulties of a definition. ASD (autism spectrum disorder) is an umbrella term encompassing several symptoms and intensities. In the last years, it has turned out that low degree of synaptic pruning plays a significant role in multiple forms of autism. We'll see in the next years how the research about synaptic pruning and learning can be used for clinical purposes. Understanding the biological mechanism can also make it easier to relate to some peculiar-sounding symptoms. If we consider that an individual's brain contains an unusually high number of synapses, their reports about unusually intense perceptions suddenly become more understandable.A thought-provoking chapter is number 6. It describes various experiments with mouse models to study autism-like symptoms. The chapter might also make you reflect about the merits and shortcomings of animal models generally.The cerebellum was long considered to be the brain area for finetuning movements. Now, it's clear that its repertoire is much bigger. In the interview, Christian describes a hypothesis that the cerebellum has a capability of timing. This in turn makes it a crucial factor in several behaviors beyond sophisticated movements, including speech.We know a lot about synaptic plasticity and its significance in learning. Chapter 8 tackles the big, open question, what else? Which other processes contribute to memory formation? It presents some hypotheses about intrinsic plasticity. Learn more about your ad choices. Visit megaphone.fm/adchoices
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Apr 27, 2024 • 1h 2min

Charan Ranganath, "Why We Remember: Unlocking Memory's Power to Hold on to What Matters" (Doubleday, 2024)

A new understanding of memory is emerging from the latest scientific research. In Why We Remember: Unlocking Memory's Power to Hold on to What Matters (Doubleday, 2024), pioneering neuroscientist and psychologist Charan Ranganath radically reframes the way we think about the everyday act of remembering. Combining accessible language with cutting-edge research, he reveals the surprising ways our brains record the past and how we use that information to understand who we are in the present, and to imagine and plan for the future.Memory, Dr. Ranganath shows, is a highly transformative force that shapes how we experience the world in often invisible and sometimes destructive ways. Knowing this can help us with daily remembering tasks, like finding our keys, and with the challenge of memory loss as we age. What's more, when we work with the brain's ability to learn and reinterpret past events, we can heal trauma, shed our biases, learn faster, and grow in self-awareness.Including fascinating studies and examples from pop culture, and drawing on Ranganath's life as a scientist, father, and child of immigrants, Why We Remember is a captivating read that unveils the hidden role memory plays throughout our lives. When we understand its power-- and its quirks--we can cut through the clutter and remember the things we want to remember. We can make freer choices and plan a happier future. Learn more about your ad choices. Visit megaphone.fm/adchoices
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Apr 16, 2024 • 1h 7min

Bobby Cherayil, "The Logic of Immunity: Deciphering an Enigma" (Johns Hopkins UP, 2024)

Most of us appreciate the importance of the immune system yet have very little knowledge about how it actually works. If you fall into this camp and are curious to learn more about this intricate system, Bobby Cherayil's book is an excellent resource.The Logic of Immunity: Deciphering an Enigma was published in January 2024 by John Hopkins University Press. It gives a great overview of this complex system, including several findings from the recent years. It also points out the many areas of ongoing research and open questions.The book introduces the actors of the system and the many interactions between them: the various types of immune cells, the pathogens and pathogen-associated patterns they recognize, the cascade of events that ultimately leads to an immune response. The opening chapter explains (and visualizes!) where these cells are located. It explains how they contribute to the immune response, and how we broadly categorize them into innate and adaptive immunity.Chapters 2 and 3 discuss the innate immune system. We get to know the general concepts, like molecular patterns and receptors recognizing them. They describe in detail some well-studied mechanisms, like the LPS-TLR4 interaction. And we also learn the story of their research spanning multiple years and multiple discoveries building upon each other.Chapters 4-6 delve into the mechanisms of adaptive immunity and their main cell types: B- and T-lymphocytes. Have you ever wondered how the immune system is able to "remember" earlier infections? You'll find here both an overview of "immune memory" and a detailed description how B and T cell proliferate and specialize.Chapter 7 shows how these immune reactions are sometimes provoked by harmless substances - that's what we call allergy. Or even by human cells - that's what we call autoimmune diseases.The next chapters put the immune system into a bigger context. They discuss the variability of immunity across different individuals and the many reasons behind it. Genes, environment, past infections, life style. A particularly fascinating part of "the human ecosystem" is the microbiota. Its importance has been recognized only in the last two decades. Chapter 8 introduces really well this emerging field of study.Chapter 11 is dedicated to an immunology topic that affects all of us: vaccines. Building upon the knowledge from previous chapters, it explains how vaccines work.Throughout the book, we learn a lot both about the exciting developments and the open questions in the field of immunology. Chapter 12 gives a summary of some trends of the last decades and an outlook for the next big puzzles to tackle. Learn more about your ad choices. Visit megaphone.fm/adchoices
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Apr 15, 2024 • 1h 18min

Miriam Piilonen, "Theorizing Music Evolution: Darwin, Spencer, and the Limits of the Human" (Oxford UP, 2024)

What did historical evolutionists such as Charles Darwin and Herbert Spencer have to say about music? What role did music play in their evolutionary theories? What were the values and limits of these evolutionist turns of thought, and in what ways have they endured in present-day music research? Theorizing Music Evolution: Darwin, Spencer, and the Limits of the Human (Oxford UP, 2024) is a critical examination of ideas about musical origins, emphasizing nineteenth-century theories of music in the evolutionist writings of Darwin and Spencer. Author Miriam Piilonen argues for the significance of this Victorian music-evolutionism in light of its ties to a recently revitalized subfield of evolutionary musicology. Taking an interdisciplinary approach to music theorizing, Piilonen explores how historical thinkers constructed music in evolutionist terms and argues for an updated understanding of music as an especially fraught area of evolutionary thought.In this book, Piilonen delves into how historical evolutionists, in particular Darwin and Spencer, developed and applied a concept of music that served as a boundary-drawing device, used to trace or obscure the conceptual borders between human and animal. She takes as primary texts the early evolutionary treatises that double as theoretical accounts of music's origins. For Darwin, music served as a kind of proto-language common to humans and animals alike; he heard the songs of birds and the chirps of mice as musical, as articulated in texts such as The Descent of Man (1871) and The Expression of the Emotions in Man and Animals (1872). Spencer, on the other hand, viewed music as a specifically human stage of evolutionary advance, beyond language acquisition, as outlined in his essay, "The Origin and Function of Music" (1857). These competing views established radically different perspectives on the origin and function of music in human cultural expression, while at the same time being mutually constitutive of one another.A ground-breaking contribution to music theory and histories of science, Theorizing Music Evolution turns to music evolution with an eye toward disrupting and intervening in these questions as they recur in the present.”Nathan Smith is a PhD candidate in Music Theory at Yale University (nathan.smith@yale.edu). Learn more about your ad choices. Visit megaphone.fm/adchoices
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Apr 14, 2024 • 1h 9min

Rasmus Winther, "Our Genes: A Philosophical Perspective on Human Evolutionary Genomics" (Cambridge UP, 2023)

Situated at the intersection of natural science and philosophy, Our Genes: A Philosophical Perspective on Human Evolutionary Genomics (Cambridge University Press, 2023) explores historical practices, investigates current trends, and imagines future work in genetic research to answer persistent, political questions about human diversity. Readers are guided through fascinating thought experiments, complex measures and metrics, fundamental evolutionary patterns, and in-depth treatment of exciting case studies. The work culminates in a philosophical rationale, based on scientific evidence, for a moderate position about the explanatory power of genes that is often left unarticulated. Simply put, human evolutionary genomics - our genes - can tell us much about who we are as individuals and as collectives. However, while they convey scientific certainty in the popular imagination, genes cannot answer some of our most important questions. Alternating between an up-close and a zoomed-out focus on genes and genomes, individuals and collectives, species and populations, Our Genes argues that the answers we seek point to rich, necessary work ahead.Rasmus Grønfeldt Winther is a philosopher of science, researcher, writer, educator, diver, and explorer. He is Professor of Humanities at University of California, Santa Cruz and Affiliate Professor of Transformative Science at the GLOBE Institute at University of Copenhagen.Caleb Zakarin is editor at the New Books Network. Learn more about your ad choices. Visit megaphone.fm/adchoices
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Apr 1, 2024 • 1h 9min

Max Bennett, "A Brief History of Intelligence: Evolution, Ai, and the Five Breakthroughs That Made Our Brains" (Mariner Books, 2023)

A Brief History of Intelligence: Evolution, Ai, and the Five Breakthroughs That Made Our Brains (Mariner Books, 2023) tells two fascinating stories. One is the evolution of nervous systems. It started 600 million years ago, when the first brains evolved in tiny worms. The other one is humans' quest to create more and more intelligent systems. This story begins in 1951 with the first reinforcement learning algorithm trying to mimic neural networks.Max Bennett is an AI entrepreneur and neuroscience researcher. His work combines insights from evolutionary neuroscience, comparative psychology, and AI. As each chapter describes how a skill evolved, it also explains whether(!) and how an AI system has managed to implement something similar. A recurring theme is how human brains and neural circuits have influenced AI architecture. The other side of this bi-directional connection is also intriguing. AI has often served as a litmus test, giving a clue how a not well understood neurobiological phenomenon might work, how plausible a hypothesis is.The organzining principle of this book is a framework of five breakthroughs, which compares evolution to technological innovation. Like a new technology enables several innovative products, a new brain capability enables several new skills. For example, mammals show several new intelligent behaviors compared to their ancestors: vicarious trial and error, episodic memory, and planning. The foundation of all these novelties, is probably the same capability: simulation.The five breakthroughs are:  steering in bilaterians learning from trial and error in vertebrates simulating in mammals mentalizing in primates speaking in humans This framework guides the readers through a time travel of 600 million years. We learn about the environment in which these capabilities evolved: Who were the first mammals and why did planning benefit them? We see what contemporary animals can and can't do: Fish aren't as dumb as folklore suggests. And we take a look at AI's baffling achievements and limitations: Why can AI write decent essays but not load a dishwasher? Learn more about your ad choices. Visit megaphone.fm/adchoices
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Mar 3, 2024 • 1h 5min

Joseph Cone, "Seeing Opera Anew: A Cultural and Biological Perspective" (Routledge, 2023)

What people ultimately want from music-drama, audience research suggests, is to be absorbed in a story that engages their feelings, even moves them deeply, and that may lead them to insights about life and, perhaps, themselves. Joseph Cone's Seeing Opera Anew: A Cultural and Biological Perspective (Routledge, 2023) shows how both human biology and culture cause these effects.Cone, a lifelong opera fan, ardent amateur singer and professional science writer, goes beyond the traditional approaches of musicology, criticism, history and biography. He adopts a "stereo" approach to assimilate cultural perspectives and contemporary evolutionary theories based in human biology. In doing so, he offers fresh insights on why music-dramas can offer such rich, immersive experiences, powerfully affecting our feelings and our understanding of life.Written to stimulate the student and opera-goer as much as the professional, "Seeing Opera Anew" examines and interprets more than 15 operas in an informal and lively way based on a range of recent scholarship. Learn more about your ad choices. Visit megaphone.fm/adchoices
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Feb 23, 2024 • 1h 21min

Sten Grillner, "The Brain in Motion: From Microcircuits to Global Brain Function" (MIT Press, 2023)

C. S. Sherrington said “All the brain can do is to move things". The Brain in Motion: From Microcircuits to Global Brain Function (MIT Press, 2023) shows how much the brain can do "just" by moving things. It gives an amazing overview of the large variety of motor behaviors and the cellular basis of them. It reveals how motor circuits provide the underlying mechanism not just for walking or jumping, but also for breath or chewing.The book emphasizes the evolutionary perspective. It demonstrates how the basic structures are the same across all vertebrates, suggesting that these systems have been around for more than 500 million years.At the very beginning, Grillner introduces the analogy of an orchestra: The microcircuits are the musicians, and the forebrain acts as the conductor. In the following chapters, the readers get to know all the important actors and their contribution to this "performance": the CPGs and motor centers that execute the movements, the tectum that synthesizes input from the direct surroundings of the animal, the basal ganglia and the cortex that together direct the microcircuits, and the cerebellum, which plays a crucial role in adapting the movements according to the environment and learning new motor behavior. The Brain in Motion provides both a great overview of the motor system and a detailed presentation of its major contributors. Learn more about your ad choices. Visit megaphone.fm/adchoices
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Feb 12, 2024 • 49min

Rob Percival, "The Meat Paradox: Eating, Empathy, and the Future of Meat" (Pegasus, 2022)

Our future diet will be shaped by diverse forces. It will be shaped by novel technologies, by geopolitical tensions, and the evolution of cultural preferences, by shocks to the status quo-- pandemics and economic strife, the escalation of the climate and ecological crises--and by how we choose to respond. It will also be shaped by our emotions. It will be shaped by the meat paradox."Should we eat animals?" was, until recently, a question reserved for moral philosophers and an ethically minded minority, but it is now posed on restaurant menus and supermarket shelves, on social media and morning television. The recent surge in popularity for veganism in the UK, Europe, and North America has created a rupture in the rites and rituals of meat, challenging the cultural narratives that sustain our omnivory.In The Meat Paradox: Eating, Empathy, and the Future of Meat (Pegasus Books, 2022), Rob Percival, an expert in the politics of meat, searches for the evolutionary origins of the meat paradox, asking when our relationship with meat first became emotionally and ethically complicated. Every society must eat, and meat provides an important source of nutrients. But every society is moved by its empathy. We must all find a way of balancing competing and contradictory imperatives. This new book is essential reading for anyone interested in the origins of our empathy, the psychology of our dietary choices, and anyone who has wondered whether they should or shouldn't eat meat.Rob Percival is Head of Policy at the Soil Association, Britain's leading food and farming charitable organization. He has been shortlisted for the Guardian's International Development Journalism Prize as well as the Thompson Reuters Food Sustainability Media Award.Caleb Zakarin is the Assistant Editor of the New Books Network (Twitter: @caleb_zakarin). Learn more about your ad choices. Visit megaphone.fm/adchoices
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Feb 10, 2024 • 1h 7min

Michael Devitt, "Biological Essentialism" (Oxford UP, 2023)

What makes a species a species? Aristotle answered the species question by positing unchanging essences, properties that all and only members of a species shared. Individuals belonged to a species by possessing this essence. Biologists and philosophers of biology today are either not essentialists at all, or if they are think there are essences they are relational, historical properties. In his provocative book Biological Essentialism (Oxford UP, 2023), Michael Devitt argues for a new form of biological essentialism in which intrinsic essences, probably largely genetic properties, are part of what tie species together and that the actual explanatory practices of biologists commit them to this view. Devitt, who is distinguished professor of philosophy, emeritus, at CUNY Graduate Center, responds to many philosophers critical of his position, and applies his essentialism to debates about race realism and anti-realism.Carrie Figdor is professor of philosophy at the University of Iowa. Learn more about your ad choices. Visit megaphone.fm/adchoices

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