New Books in Biology and Evolution

We live in an age of moral revolutions in which the once morally outrageous has become morally acceptable, and the formerly acceptable is now regarded as reprehensible. Attitudes toward same-sex love, for example, and the proper role of women, have undergone paradigm shifts over the last several decades. In this book, Robert Baker argues that these inversions are the product of moral revolutions that follow a pattern similar to that of the scientific revolutions analyzed by Thomas Kuhn in his influential book, The Structure of Moral Revolutions: Studies of Changes in the Morality of Abortion, Death, and the Bioethics Revolution (MIT Press, 2019).After laying out the theoretical terrain, Baker develops his argument with examples of moral reversals from the recent and distant past. He describes the revolution, led by the utilitarian philosopher Jeremy Bentham, that transformed the postmortem dissection of human bodies from punitive desecration to civic virtue; the criminalization of abortion in the nineteenth century and its decriminalization in the twentieth century; and the invention of a new bioethics paradigm in the 1970s and 1980s, supporting a patient-led rebellion against medical paternalism. Finally, Baker reflects on moral relativism, arguing that the acceptance of "absolute" moral truths denies us the diversity of moral perspectives that permit us to alter our morality in response to changing environments. Claire Clark is a medical educator, historian of medicine, and associate professor in the University of Kentucky’s College of Medicine. She teaches and writes about health behavior in historical context. Learn more about your ad choices. Visit megaphone.fm/adchoices

Could extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth: The Science of De-Extinction (Princeton UP, 2020), Beth Shapiro, evolutionary biologist and pioneer in “ancient DNA” research, walks readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored, to sequencing their genomes, to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used—today—to resurrect the past. Journeying to far-flung Siberian locales in search of ice age bones and delving into her own research—as well as those of fellow experts such as Svante Paabo, George Church, and Craig Venter—Shapiro considers de-extinction’s practical benefits and ethical challenges. Would de-extinction change the way we live? Is this really cloning? What are the costs and risks? And what is the ultimate goal?Using DNA collected from remains as a genetic blueprint, scientists aim to engineer extinct traits — traits that evolved by natural selection over thousands of years—into living organisms. But rather than viewing de-extinction as a way to restore one particular species, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. For example, elephants with genes modified to express mammoth traits could expand into the Arctic, re-establishing lost productivity to the tundra ecosystem.Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation’s future.Marshall Poe is the editor of the New Books Network. He can be reached at marshallpoe@newbooksnetwork.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Today I talked to Daniel Lieberman about his book Exercised: How We Did Not Evolve to Exercise and What to Do about It (Pantheon, 2021). In the book Lieberman explodes 12 different myths, chief among them we’re supposed to want to exercise. Much of the conversation explores differences between Westerners and their lifestyles, including of course exercise, versus the daily energy expenditures of non-Westerners and especially people in Africa. It provides insights to show how aging and senescence are not necessarily linked, and offers some ways in which we might enjoy exercise more.Daniel E. Lieberman is the Lerner Professor of Biological Sciences in the Department of Human Evolutionary Biology at Harvard University. He received degrees from Harvard and Cambridge Universities. Lieberman studies and teaches how and why the human body is the way it is, and how our evolutionary history affects health and disease. Dan Hill, PhD, is the author of eight books and leads Sensory Logic, Inc. (https://www.sensorylogic.com). To check out his related “Dan Hill’s EQ Spotlight” blog, visit https://emotionswizard.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

What is life? For generations, scientists have struggled to make sense of this fundamental question, for life really does look like magic: even a humble bacterium accomplishes things so dazzling that no human engineer can match it. Huge advances in molecular biology over the past few decades have served only to deepen the mystery. In this penetrating and wide-ranging book, world-renowned physicist and science communicator Paul Davies searches for answers in a field so new and fast-moving that it lacks a name; it is a domain where biology, computing, logic, chemistry, quantum physics, and nanotechnology intersect. At the heart of these diverse fields, Davies explains, is the concept of information: a quantity which has the power to unify biology with physics, transform technology and medicine, and force us to fundamentally reconsider what it means to be alive—even illuminating the age-old question of whether we are alone in the universe. From life’s murky origins to the microscopic engines that run the cells of our bodies, The Demon in the Machine: How Hidden Webs of Information Are Solving the Mystery of Life (U Chicago Press, 2020) journeys across an astounding landscape of cutting-edge science. Weaving together cancer and consciousness, two-headed worms and bird navigation, Davies reveals how biological organisms garner and process information to conjure order out of chaos, opening a window onto the secret of life itself. Learn more about your ad choices. Visit megaphone.fm/adchoices

In The Mutant Project: Inside the Global Race to Genetically Modify Humans (St. Martin's Press, 2020), anthropologist Eben Kirksey visits the frontiers of genetics, medicine, and technology to ask: Whose values are guiding gene editing experiments? And what does this new era of scientific inquiry mean for the future of the human species?At a conference in Hong Kong in November 2018, Dr. He Jiankui announced that he had created the first genetically modified babies—twin girls named Lulu and Nana—sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for “illegal medical practice.”As scientists elsewhere start to catch up with China’s vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake: Who gets access to gene editing technologies? As countries loosen regulations around the globe, from the U.S. to Indonesia, can we shape research agendas to promote an ethical and fair society?Eben Kirksey takes us on a groundbreaking journey to meet the key scientists, lobbyists, and entrepreneurs who are bringing cutting-edge genetic engineering tools like CRISPR to your local clinic. He also ventures beyond the scientific echo chamber, talking to disabled scholars, doctors, hackers, chronically-ill patients, and activists who have alternative visions of a genetically modified future for humanity.The Mutant Project empowers us to ask the right questions, uncover the truth, and navigate this brave new world.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices

Butterflies have long captivated the imagination of humans, from naturalists to children to poets. Indeed it would be hard to imagine a world without butterflies. And yet their populations are declining at an alarming rate, to the extent that even the seemingly ubiquitous Monarch could conceivably go the way of the Passenger Pigeon. Many other, more obscure, butterfly species are already perilously close to extinction. For the last 20 years, Nick Haddad has worked to identify and save some of the rarest butterflies on earth, a quest that has taken him to both surprisingly ordinary and extraordinarily inhospitable areas, including a swampy, active artillery range on a military installation in North Carolina. It has also led him to some surprising conclusions about the best ways to protect these increasingly endangered butterflies.In The Last Butterflies: A Scientist’s Quest to Save a Rare and Vanishing Creature (Princeton UP, 2019), Haddad profiles five such species – the ones he has determined to be the rarest of all – and takes us into each one’s unique habitat, life cycle, and existential challenges. From the Crystal Skipper, bouncing over sand dunes adjacent to vacation homes on barrier islands, to the Schaus’ Swallowtail, confined to increasingly remote areas of the Florida Keys, Haddad shows how human activities have affected rare butterfly populations. His unexpected conclusion is that leaving them in peace is not a viable option; disturbances, both natural and human-caused, are necessary for the ecosystems that support butterfly populations to thrive. One of the hardest lessons for him to absorb was that to save populations, some individuals have to be killed in the process.Haddad’s intrepid field work – he describes one of his strengths as “an unusual capacity to tolerate harsh environments - informs the story of each butterfly species. His lab’s effort to collect, quantify, propagate, and ultimately perpetuate, the rarest butterflies has led to increasing awareness of how much more biologists have to learn about their natural histories, and how critical such knowledge is to saving them. In perhaps the most dramatic example of unintended consequences, Haddad’s team discovered that the St. Francis Satyr, a small brown butterfly, was protected by regular artillery fire on the Fort Bragg army installation in southern North Carolina. The resulting fires were one disturbance the St. Francis Satyr needed to sustain viable conditions (dams built by beavers was another). In another twist, it turned out that Haddad’s initial efforts to help the species were having the opposite effect. Yet over time, these discoveries led to lessons that ultimately have helped the St. Francis Satyr and can be applied to other conservation efforts.The Last Butterflies could be read as a warning, but Haddad’s tone is never dire. The book is infused with enthusiasm for conservation efforts, both now and in the future, and with an admiration for the beauty, fragility, and resilience of butterflies. It is an important book for anyone concerned with biodiversity and conservation issues. It’s also an eye-opening and engaging read for anyone with an interest in butterflies.Rachel Pagones is chair of the doctoral program in acupuncture and Chinese medicine at Pacific College of Health and Science in San Diego. She is a longtime butterfly enthusiast and is working, slowly, on a fictional book for middle-grade readers about butterfly conservation. Learn more about your ad choices. Visit megaphone.fm/adchoices

As ancient creatures that once shared the Earth with dinosaurs, turtles have played a crucial role in maintaining healthy terrestrial and marine ecosystems for more than one hundred million years. While it may not set records for speed on land, the turtle is exceptional at distance swimming and deep diving, and some are gifted with astounding longevity. In human thought, the animal's ties to creativity, wisdom, and warfare stretch back to the world's earliest written records. In Turtle, Louise M. Pryke celebrates the slow and unassuming manner of this doughty creature, which provides a living model of endurance and efficiency. In the increasingly fast-paced world of the twenty-first century, it has never been more important to consider the natural and cultural history of this remarkable animal.Bede Haines is a solicitor, specialising in litigation and a partner at Holding Redlich, an Australian commercial law firm. He lives in Sydney, Australia. Known to read books, ride bikes and eat cereal (often). bede.haines@holdingredlich.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

In Pragmatism’s Evolution: Organism and Environment in American Philosophy (University of Chicago Press, 2020), Trevor Pearce demonstrates that the philosophical tradition of pragmatism owes an enormous debt to specific biological debates in the late 1800s, especially those concerning the role of the environment in development and evolution. Many are familiar with John Dewey's 1909 assertion that evolutionary ideas overturned two thousand years of philosophy--but what exactly happened in the fifty years prior to Dewey's claim? What form did evolutionary ideas take? When and how were they received by American philosophers?Although the various thinkers associated with pragmatism--from Charles Sanders Peirce to Jane Addams and beyond--were towering figures in American intellectual life, few realize the full extent of their engagement with the life sciences. In his analysis, Pearce focuses on a series of debates in biology from 1860 to 1910--from the instincts of honeybees to the inheritance of acquired characteristics--in which the pragmatists were active participants. If we want to understand the pragmatists and their influence, Pearce argues, we need to understand the relationship between pragmatism and biology.Trevor Pearce is Associate Professor in the Department of Philosophy at the University of North Carolina at Charlotte.Alec Kacew is a medical school student at the University of Chicago. Learn more about your ad choices. Visit megaphone.fm/adchoices

An estimated 80 million people live with a neurodegenerative disease, with this number expected to double by 2050. Despite decades of research and billions in funding, there are no medications that can slow, much less stop, the progress of these diseases. The time to rethink degenerative brain disorders has come. With no biological boundaries between neurodegenerative diseases, illnesses such as Parkinson's and Alzheimer's result from a large spectrum of biological abnormalities, hampering effective treatment. In Brain Fables: The Hidden History of Neurodegenerative Diseases and a Blueprint to Conquer Them (Cambridge UP, 2020), acclaimed neurologist Dr Alberto Espay and Parkinson's advocate Benjamin Stecher present compelling evidence that these diseases should be targeted according to genetic and molecular signatures rather than clinical diagnoses. There is no Parkinson's or Alzheimer's, simply people with Parkinson's or Alzheimer's. An incredibly important story never before told, Brain Fables is a wakeup call to the scientific community and society, explaining why we have no effective disease-modifying treatments, and how we can get back on track.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. You can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices

“What are chromosomes? And what does it mean to treat them as visual objects?” asks Soraya de Chadarevian in her new book, Heredity Under the Microscope: Chromosomes and the Study of the Human Genome (University of Chicago Press, 2020). Considering this question as she follows the history of microscope-based practices in chromosomal research across a variety of contexts—from the medical clinic to the study of human variation—de Chadarevian offers readers a new history of postwar human genetics. This approach enables her to argue that cytogenetics was far from just “old fashioned biology that was eventually superseded by molecular approaches” and to show the continuities and interdependencies between different methods for studying our DNA. Learn more about your ad choices. Visit megaphone.fm/adchoices