New Books in Biology and Evolution

Can your zip code predict when you will die? Should you space out childhood vaccines? Does talcum powder cause cancer? Why do some doctors recommend e-cigarettes while other doctors recommend you stay away from them? Health information―and misinformation―is all around us, and it can be hard to separate the two. A long history of unethical medical experiments and medical mistakes, along with a host of celebrities spewing anti-science beliefs, has left many wary of science and the scientists who say they should be trusted. How can we unravel the knots of fact and fiction to find out what we should really be concerned about, and what we can laugh off?In Viral BS: Medical Myths and Why We Fall for Them (Johns Hopkins UP, 2021), medical journalist, doctor, professor, and former CDC disease detective Seema Yasmin, driven by a need to set the record straight, dissects some of the most widely circulating medical myths and pseudoscience. Exploring how epidemics of misinformation and disinformation can spread faster than microbes, Dr. Yasmin asks why bad science is sometimes more believable and contagious than the facts. Each easy-to-read chapter covers a specific myth, whether it has endured for many years or hit the headlines more recently.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices

What does the birth of babies whose embryos have gone through genome editing mean—for science and for all of us?In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos—as dramatic a development in genetics as the 1996 cloning of Dolly the sheep. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences in CRISPR People: The Science and Ethics of Editing Humans (The MIT Press, 2021). Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention.The two babies, nonidentical twin girls, were the first “CRISPR'd” people ever born (CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, is a powerful gene-editing method). Greely not only describes He's experiment and its public rollout (aided by a public relations adviser) but also considers, in a balanced and thoughtful way, the lessons to be drawn both from these CRISPR'd babies and, more broadly, from this kind of human DNA editing—“germline editing” that can be passed on from one generation to the next.Greely doesn't mince words, describing He's experiment as grossly reckless, irresponsible, immoral, and illegal. Although he sees no inherent or unmanageable barriers to human germline editing, he also sees very few good uses for it—other, less risky, technologies can achieve the same benefits. We should consider the implications carefully before we proceed.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices

Vaccines make us wholly or partly immune to disease, such as Covid-19. But what is it to be immune? What is an immune system, and what does it do? In its beginnings, immunology was considered the science of the self/non-self distinction: the immune system comprised the self’s defenses against invading non-self pathogens, and was a sophisticated system possessed only by vertebrates. In Philosophy of Immunology (Cambridge University Press, 2020), Thomas Pradeu explains why these traditional conceptions have been upended over the past 20 years or so. It is now accepted that even single celled organisms have immune systems and that immune systems are also active in many biological activities, including regulation of foreign entities that are not part of the body but are not pathogens either, such as the gut microbiome. Pradeu, who is senior researcher at CNRS and University of Bordeau, defends his view of the individual as an immunologically unified chimera, and speculates about the implications for our understanding of cognition and psychiatric illness in the light of new discoveries of overlap between the immune and nervous systems. Learn more about your ad choices. Visit megaphone.fm/adchoices

A scientist assesses the potential of stem cell therapies for treating such brain disorders as stroke, Alzheimer’s disease, and Parkinson’s disease.Stem cell therapies are the subject of enormous hype, endowed by the media with almost magical qualities and imagined by the public to bring about miracle cures. Stem cells have the potential to generate new cells of different types, and have been shown to do so in certain cases. Could stem cell transplants repair the damaged brain? In his book The Future of Brain Repair: A Realist's Guide to Stem Cell Therapy (MIT Press, 2020), neurobiologist Jack Price assesses the potential of stem cell therapies to treat such brain disorders as stroke, Alzheimer’s disease, Parkinson’s disease, and spinal cord injuries.Certainly brain disorders are in need of effective treatments. These disorders don’t just kill, they disable, and conventional drug therapies have not had much success in treating them. Price explains that repairing the human brain is difficult, largely because of its structural, functional, and developmental complexity. He examines the self-repairing capacity of blood and gut cells—and the lack of such capacity in the brain; describes the limitations of early brain stem cell therapies for neurodegenerative disorders; and discusses current clinical trials that may lead to the first licensed stem cell therapies for stroke, Parkinson’s and macular degeneration. And he describes the real promise of pluripotential stem cells, which can make all the cell types that constitute the body.New technologies, Price reports, challenge the very notion of cell transplantation, instead seeking to convince the brain itself to manufacture the new cells it needs. Could this be the true future of brain repair?You can find more about Jack’s work here and here.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices

Why are humans alone capable of invention? This question is relevant to every human invention, from music to mathematics, sculpture and science, dating back to the beginnings of civilization. In The Pattern Seekers: A New Theory of Human Invention, Simon Baron-Cohen, the director of the Autism Research Center at Cambridge University, presents a new theory of human invention. His unexpected claim is that understanding autistic people — specifically their unstoppable drive to seek patterns, a characteristic of the condition — is the key to understanding both the ancient origins and the modern flowering of human creativity.In The Pattern Seekers, Simon Baron-Cohen’s goal is two-fold: to provide an answer to the long-standing question about human invention and to understand the role that autistic people played in the evolution of human invention. His higher message is to change the way our society views and treats autistic people. “Among the new generation of hypersystemizers will be some of the great inventors of our future…If we acknowledge that some autistic people were and still are the drivers of the evolution of science, technology, art, and other forms of invention, their future can be different.”Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices

A reporter uncovers the secrets behind the scientific scam of the century. The news breaks first as a tale of fear and pity. Doctors at a London hospital claim a link between autism and a vaccine given to millions of children: MMR. Young parents are terrified. Immunization rates slump. And as a worldwide ‘anti-vax’ movement kicks off, old diseases return to sicken and kill. But a veteran reporter isn’t so sure, and sets out on an epic investigation. Battling establishment cover-ups, smear campaigns, and gagging lawsuits, he exposes rigged research and secret schemes, the heartbreaking plight of families struggling with disability, and the scientific deception of our time.Brian Deer's The Doctor Who Fooled the World: Andrew Wakefield's War on Vaccines (Johns Hopkins UP, 2020) tells the troubling story of Andrew Wakefield: a man in search of greatness, who stakes his soul on big ideas that, if right, might transform lives. But when the facts don’t fit, he can’t face failure. He’ll do whatever it takes to succeed.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices

Americans today are often skeptical of scientific authority. Many conservatives dismiss climate change and Darwinism as liberal fictions, arguing that "tenured radicals" have coopted the sciences and other disciplines. Some progressives, especially in the universities, worry that science's celebration of objectivity and neutrality masks its attachment to Eurocentric and patriarchal values. As we grapple with the implications of climate change and revolutions in fields from biotechnology to robotics to computing, it is crucial to understand how scientific authority functions--and where it has run up against political and cultural barriers.Science Under Fire: Challenges to Scientific Authority in Modern America (Harvard UP, 2020) reconstructs a century of battles over the cultural implications of science in the United States. Andrew Jewett reveals a persistent current of criticism which maintains that scientists have injected faulty social philosophies into the nation's bloodstream under the cover of neutrality. This charge of corruption has taken many forms and appeared among critics with a wide range of social, political, and theological views, but common to all is the argument that an ideologically compromised science has produced an array of social ills. Jewett shows that this suspicion of science has been a major force in American politics and culture by tracking its development, varied expressions, and potent consequences since the 1920s.Looking at today's battles over science, Jewett argues that citizens and leaders must steer a course between, on the one hand, the naïve image of science as a pristine, value-neutral form of knowledge, and, on the other, the assumption that scientists' claims are merely ideologies masquerading as truths.Claire Clark is a medical educator, historian of medicine, and associate professor in the University of Kentucky’s College of Medicine. She teaches and writes about health behavior in historical context. Learn more about your ad choices. Visit megaphone.fm/adchoices

Is color a phenomenon of science or a thing of art? Over the years, color has dazzled, enhanced, and clarified the world we see, embraced through the experimental palettes of painting, the advent of the color photograph, Technicolor pictures, color printing, on and on, a vivid and vibrant celebrated continuum. These turns to represent reality in “living color” echo our evolutionary reliance on and indeed privileging of color as a complex and vital form of consumption, classification, and creation. It’s everywhere we look, yet do we really know much of anything about it? Finding color in stars and light, examining the system of classification that determines survival through natural selection, studying the arrival of color in our universe and as a fulcrum for philosophy, DeSalle’s brilliant A Natural History of Color: The Science Behind What We See and How We See it (Pegasus Books, 2020)establishes that an understanding of color on many different levels is at the heart of learning about nature, neurobiology, individualism, even a philosophy of existence. Color and a fine tuned understanding of it is vital to understanding ourselves and our consciousness.Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices

We live in an age of moral revolutions in which the once morally outrageous has become morally acceptable, and the formerly acceptable is now regarded as reprehensible. Attitudes toward same-sex love, for example, and the proper role of women, have undergone paradigm shifts over the last several decades. In this book, Robert Baker argues that these inversions are the product of moral revolutions that follow a pattern similar to that of the scientific revolutions analyzed by Thomas Kuhn in his influential book, The Structure of Moral Revolutions: Studies of Changes in the Morality of Abortion, Death, and the Bioethics Revolution (MIT Press, 2019).After laying out the theoretical terrain, Baker develops his argument with examples of moral reversals from the recent and distant past. He describes the revolution, led by the utilitarian philosopher Jeremy Bentham, that transformed the postmortem dissection of human bodies from punitive desecration to civic virtue; the criminalization of abortion in the nineteenth century and its decriminalization in the twentieth century; and the invention of a new bioethics paradigm in the 1970s and 1980s, supporting a patient-led rebellion against medical paternalism. Finally, Baker reflects on moral relativism, arguing that the acceptance of "absolute" moral truths denies us the diversity of moral perspectives that permit us to alter our morality in response to changing environments. Claire Clark is a medical educator, historian of medicine, and associate professor in the University of Kentucky’s College of Medicine. She teaches and writes about health behavior in historical context. Learn more about your ad choices. Visit megaphone.fm/adchoices

Could extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth: The Science of De-Extinction (Princeton UP, 2020), Beth Shapiro, evolutionary biologist and pioneer in “ancient DNA” research, walks readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored, to sequencing their genomes, to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used—today—to resurrect the past. Journeying to far-flung Siberian locales in search of ice age bones and delving into her own research—as well as those of fellow experts such as Svante Paabo, George Church, and Craig Venter—Shapiro considers de-extinction’s practical benefits and ethical challenges. Would de-extinction change the way we live? Is this really cloning? What are the costs and risks? And what is the ultimate goal?Using DNA collected from remains as a genetic blueprint, scientists aim to engineer extinct traits — traits that evolved by natural selection over thousands of years—into living organisms. But rather than viewing de-extinction as a way to restore one particular species, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. For example, elephants with genes modified to express mammoth traits could expand into the Arctic, re-establishing lost productivity to the tundra ecosystem.Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation’s future.Marshall Poe is the editor of the New Books Network. He can be reached at marshallpoe@newbooksnetwork.com. Learn more about your ad choices. Visit megaphone.fm/adchoices