New Books in Biology and Evolution

Based on examining physics and the practices of physicists, philosophers of science often see models in science as representational intermediaries between scientific theories and the world. But what do scientists do when they don’t yet have the models or the theories? In Interdisciplinarity in the Making: Models and Methods in Frontier Science (MIT Press, 2022), Nancy Nersessian reveals the bootstrapping creation of models in two biomedical engineering and two integrated system biology labs. Based on her cognitive ethnographic investigations, she argues that models are cognitive artifacts that are central components in distributed cognitive-cultural systems that include the scientists that create and use them. Nersessian, who is Regents’ Professor of Cognitive Science (emerita) at Georgia Institute of Technology, shows how the scientists build the epistemic infrastructure they need, along with the novel modeling practices that their cognitive artifacts enable, in order to do the science they want to do. Her teams’ investigations also led to developing award-winning curricula for science students.Carrie Figdor is professor of philosophy at the University of Iowa. Learn more about your ad choices. Visit megaphone.fm/adchoices

Annika Culver’s Japan's Empire of Birds: Aristocrats, Anglo-Americans, and Transwar Ornithology (Bloomsbury Academic 2022) uses a previously unavailable archive of photographs as the jumping off point to follow the careers of Japanese ornithologists in the transwar generation as they navigated the complexities of their swiftly changing political circumstances. Japan’s Empire of Birds brings out the tensions between aristocratic connoisseurship elegance, scientific advancement, and intense personal relationships on the one hand; and imperial and military violence and race-based power hierarchies on the other. Birds themselves embody such paradoxes and tensions: they are symbols of freedom even as we trap, train them as hunters and spies, and even eat them, and they are both nationalist symbols (every country has a national bird) while migratory birds exist as transnational transgressors in a borderless world beyond human politics. These themes underlie Culver’s exploration of networks of Japanese ornithologists and their mostly Anglo-American counterparts from the 1920s to the 1970s.Nathan Hopson is an associate professor of Japanese language and history in the University of Bergen's Department of Foreign Languages. Learn more about your ad choices. Visit megaphone.fm/adchoices

Listen to this interview of David Lindsay, emeritus professor of the University of Western Australia. We talk about his book Scientific Writing = Thinking in Words (CSIRO Publishing, 2020) and how your hypothesis can save the communication of your research.David Lindsay : "It's quite unfortunate that we're training our undergraduates in science this way. I mean, undergraduates know that when they write something, for example, a protocol to be graded—undergraduates know that their professors are seeking to find out whether the student knows something about the subject. So, as long as there's any semblance at all in the text that the student knows something about the subject, well, then the professor ticks a box and marks the student accordingly. This just encourages undergraduates to dump knowledge, to be writing any sort of rubbish just so long as something substantial-like bubbles out of it that seems to suggest that they have a reasonable understanding of the subject. But when these same undergrads get to the point of writing this way for scientific publication, well, then it all comes crashing down, because they can't just throw information together and hope that reviewers or editors will say, 'Oh, yeah, I think I can see what you mean. You know stuff.'" Learn more about your ad choices. Visit megaphone.fm/adchoices

Advances in medicine have made possible better treatments for widespread, familiar human illnesses like cancer, diabetes, and heart disease. Yet there are thousands of much less common diseases, most of genetic origin, each classed as rare because it afflicts only a small number of people. These patient groups were long ignored by a pharmaceutical industry that judged them too small to provide a return on the investment needed to develop an effective remedy. Yet these orphaned diseases collectively caused misery and expense, often far greater than did more common ailments, for tens of millions of individuals and their families.Forty years ago, a revolution that transformed the prospects of patients with rare diseases was lit by three sparks. The passage of the 1983 U.S. Orphan Drug Act resulted from public pressure brought by rare disease patients, their families, and advocates. The AIDS epidemic triggered additional activism, compounded when patients with the rare disease hemophilia became HIV-positive after infusion of tainted blood products. And the third spark was the emergence in the early 1980s of biotechnology companies like Genentech, Amgen, and Biogen employing then-new genetic engineering instead of conventional approaches to pharmaceutical development. Soon after, Genzyme became the first company to develop a treatment for a rare genetic disorder, Gaucher disease, which would come to transform the industry.Jim Geraghty has been a passionate participant in the orphan drug revolution since its inception--a leader in the field as a strategy consultant, biotechnology executive, and venture entrepreneur. Inside the Orphan Drug Revolution: The Promise of Patient-Centered Biotechnology (Cold Springs Harbor Lab Press, 2022) is in part a history, with eyewitness accounts of advances as they occurred and portraits of the pioneering scientists and physicians, tireless activists, and visionary business leaders who made the revolution happen. And it tells deeply personal stories of patients and parents willing to risk new, untried therapies. But Geraghty also uses his exceptional experience and vantage point to look forward to the immense promise of the newest technologies like gene therapy and gene editing for the treatment of patients today and tomorrow. He concludes with thoughtful consideration of important questions. Why do drugs to treat orphan diseases cost so much? How can we ensure they are affordable? How can their effectiveness be responsibly assessed? And how can access to them be expanded internationally? This book graphically and poignantly illustrates how far an important healthcare revolution has come and reminds us that if not nurtured, it could end before its immense promise has been fulfilled. Learn more about your ad choices. Visit megaphone.fm/adchoices

How should humans respond to our ongoing human-made climate catastrophe? To answer that question, Recall this Book turned to prize-winning climate reporter Elizabeth Kolbert, who visited Brandeis this Fall. The topic was Under a White Sky, her recent book that documents the responses to the climate crisis ranging from a form of climate engineering that shoots reflective particles into the air to cool the atmosphere, to negative emission technologies that capture and inject carbon dioxide underground."You'd have to be pretty hard-hearted not to feel called to some kind of action when you see what we humans have done." But Elizabeth wonders what the best alternatives are. Should we set aside half the earth for biodiversity? Why is it that genetic engineering has become the cultural flashpoint for fear of unintended consequences? There are no easy answers at this point. Elizabeth thinks that if you're not frightened by what's going right now, including American politics around vaccination refusal, you're not paying attention.Because this episode is associated with the annual Brandeis New Student Book Forum, first-year students Hedy Yang and Srinidhi Sriraman (who also goes by Nidhi) jump in with some thoughts.Noticing repeated mentions of Henry David Thoreau in the book, Nidhi inquires about his role in inspiring Elizabeth's writing. Hedy's question about environmental justice and the comparative agency of rich and poor countries moves Elizabeth to talk about the staggering inequities in consumption and the goal of convergence in carbon emissions. What is the mechanism by which this happens, though? Do humans have the right to implement these technologies? Is the solution to issues created by human control really more control?Mentioned in the Episode E.O. Wilson, Half Earth "Gene editing could revive a nearly lost tree"; the chestnut gene splicing debate in a recent Washington Post article. (Elizabeth has reported on Bill Powell's work) Mary Shelley, Frankenstein (1818) Cormac McCarthy, The Road (2006) Cli-fi: climate fiction in all its bleakness. For example, Margaret Atwood's Oryx and Crake. Kim Stanley Robinson, Ministry for the Future Rob Nixon, Slow Violence: how to see things happening at different time scales. Rachel Carson, Silent Spring (1962) Henry David Thoreau, "the touchstone" of American nature writing. e.g Walden (1854); dated yes, but "in most ways ahead of his time" Des Poissons dans le Desert: Elizabeth's book title in French! Listen to the episode here.Read the transcript here.Special credit and thanks for this episode goes to Hedy Yang and Srinidhi Sriraman, who took part in the audio editing and the preparation of the show notes, respectively. Learn more about your ad choices. Visit megaphone.fm/adchoices

Why is it so difficult to adopt a more sustainable way of life, even when convinced of the urgency of the environmental crisis? If adopting new behaviors beneficial for the environment is so challenging at the individual level, no wonder it is even harder at the community or governmental levels. Seeing individual and collective behaviors not changing, or not rapidly enough, eventually leads to the belief that nothing can be done and that human beings are just “hard-wired” that way.This is where, quite unexpectedly, neuroscience can help us tackle the multidimensional and unprecedented problem that is the environmental crisis. In Minding the Climate: How Neuroscience Can Help Solve Our Environmental Crisis (Harvard University Press, 2022), Dr. Ann-Christine Duhaime argues that by considering the long evolutionary history of the human brain and its reward-system, one can better understand, and therefore grow less frustrated about, why adopting sustainable behaviors can be so challenging. “Our brains are amazing," writes Dr. Duhaime, "– fine-tuned, capable, adaptable, to handle the incredible tasks of human life in its infinite variety and with its infinite day-to-day challenges. […] But there is a mismatch between the pace of evolution of this extraordinary able, pulsating, three-pound bundle of sparks and what we need to meet the challenge of this extraordinary rapid Age of the Anthropocene.”It is this mismatch that Dr. Duhaime proposes to analyze in this surprising book. Using insights provided by research at the intersection of neuroscience, environmental sciences and a number of other fields, Minding the Climate invites us to think about what a “sustainable brain” might look like and how to achieve it.Victor Monnin, Ph.D. is an historian of science specialized in the history of Earth sciences. He is also teaching French language and literature to undergraduates. Learn more about your ad choices. Visit megaphone.fm/adchoices

Experimentation on animals—particularly humans—is often assumed to be a uniquely modern phenomenon. But the ideas and attitudes that encourage biological and medical scientists to experiment on living creatures date from the earliest expressions of Western thought. In Experimenting with Humans and Animals: From Aristotle to CRISPR (Johns Hopkins UP, 2022) (Johns Hopkins UP), Anita Guerrini looks at the history of these practices and examines the philosophical and ethical arguments that justified them.Guerrini discusses key historical episodes in the use of living beings in science and medicine, including the discovery of blood circulation, the development of smallpox and polio vaccines, and recent research in genetics, ecology, and animal behavior. She also explores the rise of the antivivisection movement in Victorian England, the modern animal rights movement, and current debates over gene therapy and genetically engineered animals. We learn how perceptions and understandings of human and animal pain have changed; how ideas of class, race, and gender have defined the human research subject; and that the ethical values of science seldom stray far from the society in which scientists live and work.Thoroughly rewritten and updated, with new material in every chapter, the book emphasizes a broader understanding of experimentation and adds material on gene therapy, self-experimentation, and prisoners and slaves as experimental subjects. A new chapter brings the story up to the present while reflecting on the current regulatory scene, new developments in science, and emerging genomics. Experimenting with Humans and Animals offers readers a context within which to understand more fully the responsibility we all bear for the suffering inflicted on other living beings in the name of scientific knowledge.Anita Guerrini is a historian of science and medicine, recently retired as Horning Professor in the Humanities at Oregon State University, where she's been since 2008. Before that she was a professor of History and Environmental Studies at the University of California, Santa Barbara. She was educated at Connecticut College and Oxford University and received a Ph.D. in History and Philosophy of Science from Indiana University.Callie Smith is a poet and a PhD candidate in English at the University of Louisiana at Lafayette. Learn more about your ad choices. Visit megaphone.fm/adchoices

Who are America's creationists? What do they want? Why do they think Jesus rode around on a dinosaur? In Creationism USA: Bridging the Impasse on Teaching Evolution (Oxford UP, 2021), Adam Laats reveals that common misconceptions about creationism have led Americans into a full century of unnecessary culture-war histrionics about evolution education and creationism. In fact, America does not now and never has had deep, fundamental disagreement about evolution. Not about the actual science of evolution, that is, and not in ways that truly matter to public policy. Americans do have significant disagreements about creationism, though, and Laats offers a new way to understand those battles. By describing the history of creationism and its many variations, this book demonstrates that the real conflict about evolution is not between creationists and evolution. The true landscape of American creationism is far more complicated than headlines suggest.Your host, Ryan Shelton (@_ryanshelton) is a social historian of British and American Protestantism and a PhD researcher at Queen’s University Belfast. Learn more about your ad choices. Visit megaphone.fm/adchoices

Opossums in the wild don't make it to the age of three; our pet cats can live for a decade and a half; cicadas live for seventeen years (spending most of them underground). Whales, however, can live for two centuries and tubeworms for several millennia. Meanwhile, human life expectancy tops out around the mid-eighties, with some outliers living past 100 or even 110. Is there anything humans can learn from the exceptional longevity of some animals in the wild? In Methuselah's Zoo: What Nature Can Teach Us about Living Longer, Healthier Lives (MIT Press, 2022), Steven Austad tells the stories of some extraordinary animals, considering why, for example, animal species that fly live longer than earthbound species and why animals found in the ocean live longest of all.Austad--the leading authority on longevity in animals--argues that the best way we will learn from these long-lived animals is by studying them in the wild. Accordingly, he proceeds habitat by habitat, examining animals that spend most of their lives in the air, comparing insects, birds, and bats; animals that live on, and under, the ground--from mole rats to elephants; and animals that live in the sea, including quahogs, carp, and dolphins.Humans have dramatically increased their lifespan with only a limited increase in healthspan; we're more and more prone to diseases as we grow older. By contrast, these species have successfully avoided both environmental hazards and the depredations of aging. Can we be more like them?Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. Learn more about your ad choices. Visit megaphone.fm/adchoices

The natural world teems with remarkable conversations, many beyond human hearing range. Scientists are using groundbreaking digital technologies to uncover these astonishing sounds, revealing vibrant communication among our fellow creatures across the Tree of Life.At once meditative and scientific, The Sounds of Life: How Digital Technology Is Bringing Us Closer to the Worlds of Animals and Plants (Princeton UP, 2022)shares fascinating and surprising stories of nonhuman sound, interweaving insights from technological innovation and traditional knowledge. We meet scientists using sound to protect and regenerate endangered species from the Great Barrier Reef to the Arctic and the Amazon. We discover the shocking impacts of noise pollution on both animals and plants. We learn how artificial intelligence can decode nonhuman sounds, and meet the researchers building dictionaries in East African Elephant and Sperm Whalish. At the frontiers of innovation, we explore digitally mediated dialogues with bats and honeybees. Technology often distracts us from nature, but what if it could reconnect us instead?The Sounds of Life offers hope for environmental conservation and affirms humanity's relationship with nature in the digital age. After learning about the unsuspected wonders of nature's sounds, we will never see walks outdoors in the same way again. Learn more about your ad choices. Visit megaphone.fm/adchoices