

Big Picture Science
Big Picture Science
The surprising connections in science and technology that give you the Big Picture. Astronomer Seth Shostak and science journalist Molly Bentley are joined each week by leading researchers, techies, and journalists to provide a smart and humorous take on science. Our regular "Skeptic Check" episodes cast a critical eye on pseudoscience.
Episodes
Mentioned books

Sep 2, 2019 • 54min
Skeptic Check: Data Bias
Sexist snow plowing? Data that guide everything from snow removal schedules to heart research often fail to consider gender. In these cases, “reference man” stands in for “average human.” Human bias also infects artificial intelligence, with speech recognition triggered only by male voices and facial recognition that can’t see black faces. We question the assumptions baked into these numbers and algorithms.Guests:
Caroline Criado-Perez - Journalist and author of “Invisible Women: Data Bias in a World Designed for Men”
Kade Crockford - Director of the Technology for Liberty Program at the ACLU of Massachusetts
Amy Webb - Futurist, founder and CEO of the Future Today Institute, and author of “The Big Nine: How the Tech Titans and There Thinking Machines Could Warp Humanity”
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Aug 26, 2019 • 54min
Skeptic Check: Brain Gain
(repeat) Looking to boost your brainpower? Luckily, there are products promising to help. Smart drugs, neurofeedback exercises, and brain-training video games all promise to improve your gray matter’s performance. But it’s uncertain whether these products really work. Regulatory agencies have come down hard on some popular brain training companies for false advertising. But other brain games have shown benefits in clinical trials. And could we skip the brain workout altogether and pop a genius pill instead? In our monthly look at critical thinking, we separate the pseudo from the science of commercial cognitive enhancement techniques.Guests:
Caroline Williams– Science journalist and author of “My Plastic Brain: One Woman’s Yearlong Journey to Discover If Science Can Improve Her Mind”
Adam Gazzaley– Neuroscientist, University of California, San Francisco, and the executive director of Neuroscape. His book is “The Distracted Mind: Ancient Brains in a High Tech World.”
Amy Arnsten– Professor of neuroscience and psychology at Yale Medical School
Kevin Roose– Journalist for the New York Times.
Leonard Mlodinow– Physicist and author of “Elastic: Flexible Thinking in a Time of Change”
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Aug 19, 2019 • 54min
True Grit
Without sand, engineering would be stuck in the Middle Ages. Wooden houses would line mud-packed streets, and Silicon Valley would be, well, just a valley. Sand is the building material of modern cities, and we use more of this resource than any other except water and air. Now we’re running out of it. Hear why the Roman recipe for making concrete was lost until the 19th century, and about the super-secret mine in North Carolina that makes your smartphone possible. Plus, engineered sand turns stormwater into drinking water, and why you might think twice about running barefoot on some tropical beaches once you learn about their biological source.And, a special report from the coast of Louisiana where livelihoods and ecosystems depend on the successful release of Mississippi sand from levees into sediment-starved wetlands.Guests:
Vince Beiser – Journalist and author of “The World in a Grain: The Story of Sand and How it Transformed Civilization”
Joe Charbonnet – Science and policy associate at the Green Science Policy Institute in Berkeley, California
Pupa Gilbert – Biophysicist and geobiologist, University of Wisconsin, Madison
Rudy Simoneaux – Engineer manager, Coastal Protection and Restoration Authority, Baton Rouge, Louisiana
Elizabeth Chamberlain – Post-doctoral researcher in Earth and Environmental Sciences, Vanderbilt University
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Aug 12, 2019 • 54min
Granting Immunity
“Diversity or die” could be your new health mantra. Don’t boost your immune system, cultivate it! Like a garden, your body’s defenses benefit from species diversity. Find out why multiple strains of microbes, engaged in a delicate ballet with your T-cells, join internal fungi in combatting disease. Plus, global ecosystems also depend on the diversity of its tiniest members; so what happens when the world’s insects bug out?Guests:
Matt Richtel – Author, most recently, of “An Elegant Defense: The Extraordinary New Science of The Immune System”
Rob Dunn – Biologist and professor in the Department of Biological Sciences at North Carolina State University. Author of “Never Home Alone”
David Underhill – Professor of medicine, Cedars-Sinai Hospital, Los Angeles, California
Anne Sverdrup-Thygeson – Professor in conservation biology at the Institute for Ecology and Nature Management at the Norwegian University of Life Sciences. Author of “Buzz, Sting, Bite: Why We Need Insects”
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Aug 5, 2019 • 54min
Sci-Fi From the Future
(repeat) Are you ready to defer all your personal decision-making to machines? Polls show that most Americans are uneasy about the unchecked growth of artificial intelligence. The possible misuse of genetic engineering also makes us anxious. We all have a stake in the responsible development of science and technology, but fortunately, science fiction films can help.The movies Ex Machina and Jurassic Park suggest where A.I. and unfettered gene-tinkering could lead. But even less popular sci-fi movies can help us imagine unsettling scenarios regarding over-population, smart drugs, and human cloning. And not all tales are grim. The 1951 film, The Man in the White Suit, weaves a humorous story of materials science run amok. So, grab a bowl of popcorn and join us in contemplating the future of humanity as Hollywood sees it!Guest:
Andrew Maynard – Physicist and professor at the School for the Future of Innovation in Society at Arizona State University. Author of Films from the Future: The Technology and Morality of Sci-Fi Movies. Learn more about your ad choices. Visit megaphone.fm/adchoices

Jul 29, 2019 • 54min
Skeptic Check: Flat Earth
(repeat) The Earth is not round. Technically, it’s an oblate spheroid. But for some people, the first statement is not even approximately correct. Flat Earthers believe that our planet resembles – not a slightly squashed grapefruit – but a thick pancake. A journalist who covered a Flat Earth convention describes the rationale behind this ever-more popular belief. So how do you establish science truth? We look at the difference between a truly scientific examination of extraordinary claims and approaches that feel and look science-y but aren’t. Find out how one man will use telescopes and balloons in the desert to demonstrate that the Earth is a globe, while a biologist runs a test on the waters of Loch Ness to see if it contains prehistoric reptile DNA.And what happens when amateur investigators chase ghosts, UFOs, and Bigfoot with science instruments, but without an understanding of the scientific method.Guests:
James Underdown– Executive Director of the Center for Inquiry in Los Angeles and of the Independent Investigations Group. The results of his experiment will be posted here.
Alex Moshakis– Journalist who writes for the Observer, the Guardian, and Esquire. His article on the U.K.’s first Flat Earth convention appeared in May, 2018 in the
Harry Dyer– Lecturer in education at the University of East Anglia. His article about the flat earth convention is titled "I Watched an Entire Flat Earth Convention for my Research, Here is What I Learned."
Neil Gemmell– Professor in the Department of Anatomy, University of Otago, New Zealand
Sharon Hill– Geologist, science writer, speaker, and author of "Scientifical Americans: The Culture of Amateur Paranormal Researchers."
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Jul 22, 2019 • 54min
Let's Stick Together
Crowded subway driving you crazy? Sick of the marathon-length grocery store line? Wish you had a hovercraft to float over traffic? If you are itching to hightail it to an isolated cabin in the woods, remember, we evolved to be together. Humans are not only social, we’re driven to care for one another, even those outside our immediate family. We look at some of the reasons why this is so – from the increase in valuable communication within social groups to the power of the hormone oxytocin. Plus, how our willingness to tolerate anonymity, a condition which allows societies to grow, has a parallel in ant supercolonies.Guests:
Adam Rutherford – Geneticist and author of “Humanimal: How Homo sapiensBecame Nature’s Most Paradoxical Creature – a New Evolutionary History”
Patricia Churchland – Neurophilosopher, professor of philosophy emerita at the University of California San Diego, and author most recently of “Conscience: The Origins of Moral Intuition”
Mark Moffett – Tropical biologist, Smithsonian Institution researcher, and author of “The Human Swarm: How Our Societies Arise, Thrive and Fall”
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Jul 15, 2019 • 54min
Math's Paths
If you bake, you can appreciate math’s transformative properties. Admiring the stackable potato chip is to admire a hyperbolic sheet. Find out why there’s no need to fear math - you just need to think outside the cuboid. Also, how nature’s geometric shapes inspire the next generation of squishy robots and an argument for radically overhauling math class. The end point of these common factors is acute show that’s as fun as eating Pi.Guests:
Eugenia Cheng – Scientist in Residence at the School of the Art Institute in Chicago, tenured at the School of Mathematics and Statistics at the University of Sheffield, and author of “How to Bake Pi”
Shankar Venkataramani – Professor of math at the University of Arizona
Steven Strogatz – Professor of applied mathematics at Cornell University and author of “Infinite Powers: How Calculus Reveals the Secrets of the Universe”
Daniel Finkel – Mathematician and founder and director of operations at “Math for Love”
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Jul 8, 2019 • 54min
DNA is Not Destiny
(repeat) Heredity was once thought to be straightforward. Genes were passed in an immutable path from parents to you, and you were stuck – or blessed – with what you got. DNA didn’t change. But now we know that’s not true. Epigenetic factors, such as your environment and your lifestyle, control how your genes are expressed. Meanwhile, the powerful tool CRISPR allows us to tinker with the genes themselves. DNA is no longer destiny.Hear the results from the NASA twin study and what happened to astronaut Scott Kelly’s DNA after a year on the International Space Station. Plus, whether there’s evidence that epigenetic changes can be passed down. And, if we can wipe out deadly malaria by engineering the mosquito genome for sterility, should we do it?Guests:
Scott Kelly – Former military test pilot and astronaut and author of “Infinite Wonder”
Carl Zimmer – Columnist for The New York Times, author of “She Has Her Mother’s Laugh: The Powers, Perversions, and Potential of Heredity"
Christopher Mason – Associate professor of genetics and computational biology at Weill Cornell Medicine
Michael Snyder – Chair of the genetics department and director of the Center for Genomics and Precision Medicine at Stanford University
Nicole Gladish – PhD candidate, department of medical genetics, University of British Columbia
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Jul 1, 2019 • 54min
Nailing the Moon Landing
Neil, Buzz, and Michael made it look effortless, but the moon landing was neither easy nor inevitable. Soon after President Kennedy publicly stated the goal of sending Americans to the moon, NASA confessed that the chances of success were only about 50/50. But on July 20, 1969, despite enormous difficulties, astronauts stepped onto the lunar regolith.In this special anniversary episode, we go behind the iconic phrases and familiar photos to consider the errors, mishaps, and the Plan B contingencies that dogged the project, as well as hear of the hundreds of thousands of men and women who made Apollo 11 possible. Guests:
Charles Fishman - author of “One Giant Leap: The Impossible Mission that Flew Us to the Moon”
Matt Hayes - President and CEO of the Museum of Flight, Seattle
Geoff Nunn – Adjunct curator for Space History at the Museum of Flight.
David Whitehouse – Journalist, broadcaster, and author of “Apollo 11: The Inside Story”
Dee O’Hara – NASA’s first aerospace nurse and flight nurse for the Apollo mission
James Allen Joki – EMU Flight Controller, Apollo Mission Control, Houston.
Ted Huetter – Museum of Flight public relations manager.
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