In this special episode on SGLT-2 inhibitors and CKD Drs. John Russell and Neil Skolnik discuss the effects of the SGLT-2 inhibitors in decreasing progression of chronic kidney disease.    This special episide is supported by independent educational grant from AstraZeneca. For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Background, Epidemiology, and Pathophysiology of Diabetic Kidney Disease ADA Recommendations for Screening and Diagnosis of Diabetic Kidney Disease ADA Recommendations for Treatment of CKD in Persons with Diabetes Review of the Literature SGLT-2 inhibitor effects on CV and Kidney Outcomes in Patients with T2DM Dapagliflozin in Patients with Chronic Kidney Disease CKD Testing in Patients with T2DM Second-Line Therapy for T2DM Management: The Treatment/Benefit Paradox of CV and Kidney Comorbidities eGFR dip After Starting SGLT-2 inhibitors Dapagliflozin in patients with T2DM and Stages 3b–4 chronic kidney disease Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

Diabetes Core Update – September 2021 Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This issue will review: Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes Chronic Kidney Disease Testing Among Primary Care Patients With Type 2 Diabetes Across 24 U.S. Health Care Organizations Nutritional basis of type 2 diabetes remission Chronic Kidney Disease Testing Among At-Risk Adults in the U.S. Remains Low: Real-World Evidence from ational Laboratory Database Preparing for the NASH Epidemic: A Call to Action Diabetes and COVID-19: Population Impact 18 Months Into the Pandemic For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This issue will review: High out-of-pocket health care cost burden among Medicare beneficiaries with diabetes, 1999-2017 Effect of Continuous Glucose Monitoring on Glycemic Control in Patients With Type 2 Diabetes Treated With Basal Insulin Association of Real-time Continuous Glucose Monitoring With Glycemic Control and Acute Metabolic Events Among Patients With Insulin-Treated Diabetes Trends in Diabetes Treatment and Control in U.S. Adults, 1999–2018 Weight Loss by Low-Calorie Diet Versus Gastric Bypass Surgery in People With Diabetes Results in Divergent Brain Activation Patterns: A Functional MRI Study The Women’s Leadership Gap in Diabetes: A Call for Equity and Excellence   For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This issue will review: High Burden of Subclinical and Cardiovascular Disease Risk in Adults With Metabolically Healthy Obesity Comparison of Once-Weekly Insulin Icodec Titration Strategies Versus Once-Daily Insulin Glargine U100 Land Cover of Early-Life Environment Modulates the Risk of Type 1 Diabetes Switching to Once-Weekly Insulin Icodec Versus Once-Daily Insulin Glargine U100 in Type 2 Diabetes Inadequately Controlled on Daily Basal Insulin Projecting the Incidence of Type 2 Diabetes-Related End- Stage Kidney Disease until 2040: A Comparison between the Effects of Diabetes Prevention and Treatment with an SGLT2 Inhibitor Barriers to Technology Use and Endocrinology Care for Underserved Communities With Type 1 Diabetes   For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This issue will review: Proportion of Patients in Primary Care Meeting 2021 ADA Recommendations for GLP-1 RA and SGLT-2 Inhibitor Use Decrease in Rate of Acute Diabetes Complications in People With Type 1 or Type 2 Diabetes After Initiation of Flash Glucose Monitoring Benefits of Interruptions to Sitting Time for Glucose and Insulin Levels in People with Type 2 Diabetes Renal replacement therapy in people with and without diabetes, 2010–2016 Feasibility of Simplification From a Basal-Bolus Insulin Regimen to a Fixed-Ratio Formulation of Basal Insulin Plus a GLP-1RA or to Basal Insulin Plus an SGLT2 Inhibitor Risk Sodium-glucose co-transporter-2 inhibitors and all-cause Mortality   For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This issue will review: Body Weight Changes During Pandemic-Related Shelter-in-Place Risk of Progression to Diabetes Among Older Adults with Prediabetes Cardiovascular, Renal, and Metabolic Outcomes of Dapagliflozin Versus Placebo in a Primary Cardiovascular Prevention Cohort: Analyses From DECLARE-TIMI 58 Diet quality and all-cause mortality Exposure to Gestational Diabetes Mellitus in utero and Daily Energy Intake, Brain Responses to Food Cues and Adiposity in Children Risk Type 2 Diabetes Subgroups, Risk for Complications, and Differential Effects Due to an Intensive Lifestyle Intervention   For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This issue will review: Semaglutide for Weight Loss Sulfonylureas, and Insulin Treatment in the Elderly with Type 2 Diabetes and Risk of Severe Hypoglycemia and Death Timing of Physical Activity and its Association with Cardiovascular Health in Type 2 Diabetes Association of Metabolic Phenotypes with Coronary Artery Disease and Cardiovascular Events Changes in Risk of Cardiovascular Outcomes in Patients with Type 2 Diabetes After Addition of SGLT2 Inhibitors Versus Sulfonylureas to Baseline GLP-1RA Therapy Changes in Albuminuria Predict Cardiovascular and Renal Outcomes in Type 2 Diabetes For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

In this third episode of a three-part series on SGLT-2 inhibitors Drs. John Russell and Neil Skolnik discuss the effects of the SGLT-2 inhibitors in heart failure in persons with and without diabetes.  In episode 1, Drs. Russell and Skolnik discussed an overview of the CVOTs for the SGLT-2 inhibitors and in episode 2 they focused on renal outcomes.  This special three-part series is supported by independent educational grant from AstraZeneca. For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This issue will review: Dulaglutide 3.0 mg and 4.5 mg Versus Dulaglutide 1.5 mg Autonomous Artificial Intelligence for Diagnosing Diabetic Retinopathy in Youth Prediabetes, Diabetes, and the Risk of All-Cause and Cause-Specific Mortality Effects of iGlarLixi up to 52 weeks in type 2 diabetes Comparative effectiveness and safety of SGLT2 inhibitors vs. GLP-1 receptor agonists in Older Adults Changes in Plant-Based Diet Indices and Subsequent Risk of Type 2 Diabetes   For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health

In this special edition of Diabetes Technology three diabetes experts join us to discuss to potential for improvement in care of persons with diabetes with the use of diabetes technology.    This special edition is supported by unrestricted educational grants to the American Diabetes Association from Abbott Diabetes Care and Dexcom. For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health Mansur Shomali, M.D, founding physician of the Diabetes & Endocrine Center at MedStar Union Memorial Hospital in Baltimore, MD, Adjunct Associate Professor of Medicine at the University of Maryland School of Medicine in Baltimore, and Chief Medical Officer at Welldoc. Eden Miller, D.O., Executive Director and Co-Founder of Diabetes Nation and in practice at Diabetes and Obesity Care, St. Charles Hospital, Bend, Oregon.  Eugene Wright, M.D. Medical Director for Performance Improvement at the Charlotte Area Health Education Center.