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Mendelspod Podcast

Latest episodes

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Jul 31, 2015 • 8min

Tim Triche on Using Arrays for Cancer Research

We recently interviewed cancer researcher Tim Triche from Children's Hospital Los Angeles. Tim had two main points: First, microarrays are still a very valuable tool for research and for the clinic. Second, there are perhaps more answers for cancer research to be found in the non-coding portion of the genome than in the genes.Here, we've compiled Tim's comments on the staying power of arrays. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe
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Jul 28, 2015 • 23min

Thermo’s Chris Linthwaite on Sequencing the Ebola Virus and the Future of Public Health

Major outbreaks of deadly viruses, such as the recent spread of Ebola in Northern Africa, are nothing new on planet earth. What is new is the technology that we are using to identify, track, and contain such plagues. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe
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Jul 23, 2015 • 22min

A Tool to Strengthen the Voice of Science in Online Journalism

Emmanuel Vincent is the founder of Climate Feedback, a project which includes a new tool for scientists to comment directly on climate science news. The tool is a plugin which can be downloaded for free and gives a viewer real time access to the feedback of scientists on a particular online article. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe
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Jul 21, 2015 • 22min

Father of Child with Rare Disease Says Science Equals Medicine

Matt Might came knocking on the door of genomic medicine out of pure necessity. After a four year diagnostic odyssey that led them to Duke University, Matt and his wife, Cristina, finally found out through exome sequencing that their son, Bertrand, was suffering from a rare disease known as NGLY1 deficiency. That was three years ago. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe
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Jul 17, 2015 • 26min

Bina CEO Details Secret to Success in NGS Informatics

Last year, pharma giant Roche went on a buying spree, picking up one company after another. In December, when it was announced they had bought out Bina Technologies, many of us were playing catch up. Who is Bina, and how do they fit in the overall bioinformatics space? This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe
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Jul 14, 2015 • 19min

Cancer Researcher Tim Triche on the Staying Power of Microarrays

In the second part of our interview with Tim Triche, Director of the Personalized Medicine Center at Children’s Hospital Los Angeles, Tim says that micro arrays are still a vital technology for today’s cancer researcher. Making use of both next-gen sequencing and arrays for his research, Tim confirms that arrays still have advantages in the clinic as well, such as quicker turn around time. Tim also weighs in on some ongoing questions about whether poor biospecimen quality is hampering research efforts and whether genomic medicine is paying off for patients. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe
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Jul 9, 2015 • 25min

Want Answers? Look to the Non-Coding Region of the Genome, Says Cancer Researcher, Tim Triche

Listen to Tim Triche from Children's Hospital Los Angeles for very long and you’ll get excited again about cancer research. I couldn’t stop listening. Which is why his interview is being published in two parts.Now sure, like other guests we’ve had on the show, Tim calls this the “absolute golden age of biomedical research.” But Tim has a unique story. He has been, and is still - though less so now, he says - an outlier in cancer genomics. Whereas most cancer researchers talk about genes, Tim is more interested in non-coding RNA. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe
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Jul 7, 2015 • 33min

Ivan Oransky on Today's Retraction Boom

When science journalist Ivan Oransky co-founded Retraction Watch, a blog with the express purpose of making scientific retractions more public, he didn’t think he would be posting much.“Adam Marcus, my co-founder, was quoted as saying, ‘yeah, we figured we’d post periodically, our mothers would read it, they’d be very happy, nobody would read it other than them.’ Obviously that hasn’t been the case,” says Oransky in this first of a series of podcasts on scientific integrity. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe
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Jun 26, 2015 • 6min

Genomics-Palooza, Diagnostics Fraud, and Biblical Prophets on the Future of Biotech

What a week for Americans . . . What a week for genomics!The Supreme Court rulings that Americans can keep their Obamacare and can all get married - no matter what state they live in - added the final good news to a week of genomics festivities around the country.But it's not all positive news this week. The New York Times featured a diagnostics company under review by Medicare for fraud. Allegedly, the New Orleans based Renaissance Rx has been paying doctors to sign up patients for a huge trial of genomic based tests, even when the patients didn't qualify. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe
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Jun 24, 2015 • 29min

Ethical Issues around Editing Human Germline for the Future. Today It's about Plants and Animals, Says NYU's Art Caplan

Art Caplan is a prodigious writer on the topic of medical ethics. How prodigious? How about thirty-two books and over 700 peer reviewed papers on ethical conundrums ranging from organ donation to end of life care. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.mendelspod.com/subscribe

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