Profile

Helen Grady profiles Professor Sir Andre Geim who is one of the most unusual scientists working in Britain - perhaps the world - today.This week he was awarded the Royal Society's Copley Medal, believed to be the world's oldest science prize, for his ground-breaking experiments using graphene - thought by many to be the miracle material of the 21st century.He is also a winner of both the Ig Nobel Prize for improbable research and the real Nobel Prize in Physics. "What we should be doing with is Andre," one former boss tells us, "is just give him money to go and play, because by going and playing he's much more likely to come up with something revolutionary".Producer: Mark Savage.

Edward Stourton profiles Samantha Cameron. There's been debate this week about the degree to which her views influence government policy. But what do we actually know about the Prime Minister's wife?The daughter of a baronet with a family estate in Lincolnshire, Samantha Cameron was born Samantha Sheffield. She grew up in Oxfordshire but moved to Marlborough College in Wiltshire, where she took her A' Levels before studying Art at Camberwell College and Bristol Polytechnic.She met David Cameron through his sister - a close schoolfriend - and they married the same year that she started her career at the British luxury accessories brand, Smythson. She has been credited with reinventing the brand by introducing a popular line of handbags.Three years into her role as Prime Minister's wife, how is she handling life in Number 10?

With the Ashes underway, Mark Coles profiles the England cricket captain Alastair Cook. Born on Christmas Day in 1984, Cook's first career was as a chorister at St Paul's Cathedral. A talented musician, he also studied the clarinet and the saxophone but cricket soon took over and he made his England Test debut at 21, scoring a century. He's hit more Test centuries for England than any other player but shuns celebrity and spends his spare time sheep farming.

This week the football world ascended dizzying heights of breathlessness over the retirement of Sir Alex Ferguson. But as one footballing titan steps down, another - a man who is, in some ways, the antithesis of Sir Alex - is about to step up to take on one of the highest-profile jobs in world football. Tim Franks profiles Pep Guardiola, and asks whether he could be Sir Alex's successor as perhaps the most successful manager in the game.

As she wages war against tax avoidance, Margaret Hodge - Chair of the Public Accounts Committee - is enjoying a blazing Indian summer in her political life. As Edward Stourton discovers, her political journey is set against the background of a turbulent personal life that began as the daughter of Jewish refugees in Egypt.

Alisher Usmanov has just been named the richest man in Britain. Born in Uzbekistan, Usmanov made his fortune in the collapsing Soviet Union. His empire has stretched from plastic bags to minerals, telecoms, Facebook and Arsenal Football Club. But, as Mark Coles reports, Usmanov's rise has not been straightforward, nor free of controversy.

Mark Coles profiles the long-serving and influential head of the FBI, Robert Mueller. Mueller took on the job one week before the 2001 World Trade Center attacks. Now, as he approaches retirement, the FBI is again dealing with the aftermath of an attack on American soil.The squared-jawed Princeton graduate was decorated for bravery during the Vietnam War before training as a lawyer. Dissatisfied with private practice, he found a government job as assistant US attorney in San Francisco - a move which marked the beginning of a steady climb to the top of law enforcement in America.He transformed the FBI from an organisation that solves crimes into one that also seeks to prevent terrorist attacks. He's now the longest-serving FBI director since J Edgar Hoover. Yet surprisingly little is known about him.

Mary Ann Seighart profiles Elizabeth Llewellyn, the daughter of Jamaican immigrants, who had an obvious talent for singing from an early age. Her school-teachers in south London encouraged her to take lessons and go to concerts, and she won a place at the Royal Northern College of Music. But ill-health forced her to drop out. She then pursued an alternative career in IT recruitment, her talent lying dormant. But when, years later, she joined an amateur choir, her new colleagues urged her to take her voice more seriously. She auditioned for the Glyndebourne chorus and from that point on her rise has been meteoric.

Amazon first became the world's biggest bookshop and then went on to revolutionise shopping as we know it. What began in 1994 as a small start-up in a Seattle suburb has become arguably the most significant technology company on the planet. Jeff Bezos, Amazon's founder, is now a billionaire many times over. Bezos rarely makes public pronouncements and avoids media interviews. Those who have worked with him describe him as a hands-on manager, who plans the grand strategy as a well as the tiny details. His wealth has given him the opportunity to pursue a passion for space travel. He has been building research facilities in a remote part of Texas for a secretive space programme. But who exactly is Jeffrey Preston Bezos?Producer: Ian Muir-Cochrane.

Mary Ann Sieghart profiles the Reverend Lucy Winkett, Rector of St James's Piccadilly, and a former Canon of St Paul's Cathedral in London. Many inside the Church see her as favourite to become the first female bishop of the Church of England, if the rules change.Lucy Winkett read history at Cambridge before studying theology, and then trained as a soprano at the Royal College of Music for a year, even though she'd already decided to enter the priesthood. She uses her musical and creative side in her ministry, too, and has been known to burst into a rendition of Aretha Franklin's Natural Woman while playing the piano after morning service.Her appointment to St Paul's was controversial at the time and was initially tough for Lucy Winkett. Some couldn't accept the presence of a woman priest, and refused to take communion from her. But today her supporters are, it seems, many.Producer Fiona Leach.