CNN One Thing

New CNN polling shows historically low approval ratings for President Donald Trump as he moves past his 100th day in office. We hear from a first-time Trump voter how he feels about his vote now and look at how the Trump administration may approach the next 100 days.  Guest: Alayna Treene, CNN White House Reporter  Have a tip or question about the new Trump administration? Call us at 202-240-2895.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

Ahead of this year’s Kentucky Derby, horse racing critics are asking familiar questions about animal safety and care in an industry fueled by gambling. We examine how high-profile horse deaths and an FBI investigation into doping allegations have pushed the sport towards reforms. Guest: Katie Bo Lillis, CNN Senior Reporter & Author, “Death of a Racehorse: An American Story” Learn more about your ad choices. Visit podcastchoices.com/adchoices

Defense Secretary Pete Hegseth is under fire following revelations that he shared detailed military plans on a second Signal group chat. It comes amid infighting with his closest advisers. We examine the unfolding drama at the Pentagon and how it could impact military operations.Guest: Haley Britzky, CNN National Security ReporterHave a tip or question about the new Trump administration? Call us at 202-240-2895. Learn more about your ad choices. Visit podcastchoices.com/adchoices

A look back on the life, papacy and legacy of Pope Francis Learn more about your ad choices. Visit podcastchoices.com/adchoices

Harvard University is refusing to make key policy changes requested by the Trump administration, kicking off a funding fight with students and researchers caught in the middle. We look at what’s next for other universities and hear from incoming Harvard and Columbia freshmen about how they feel about their college choices now.Have a tip or question about the new Trump administration? Call us at 202-240-2895. Learn more about your ad choices. Visit podcastchoices.com/adchoices

President Donald Trump and El Salvador's president Nayib Bukele have both made clear in recent days that the Maryland man who was mistakenly deported to El Salvador won’t be returned to the United States. We hear why Bukele is so eager to work with Trump on immigration issues and get a firsthand account of the notorious mega-prison Kilmar Armando Abrego Garcia is being held in.Guest: David Culver, CNN Senior National CorrespondentHave a tip or question about the new Trump administration? Call us at 202-240-2895. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Researchers and study participants across the country are grappling with the abrupt cancellation of hundreds of research grants directed by the Trump administration. We hear from one researcher who believes anti-DEI policies led to the defunding of her clinical trials.Guest: Katie Edwards, University of Michigan Professor of Social WorkHave a tip or question about the new Trump administration? Call us at 202-240-2895. Learn more about your ad choices. Visit podcastchoices.com/adchoices

As President Donald Trump plows ahead with his plan to impose massive tariffs on America’s trading partners, fear and uncertainty have taken hold from Wall Street to Main Street. We examine how the administration is handling blowback from the business world and look at how your finances could be impacted.Guest: Phil Mattingly, CNN Chief Domestic Correspondent & AnchorHave a tip or question about the new Trump administration? Call us at 202-240-2895. Learn more about your ad choices. Visit podcastchoices.com/adchoices

As DOGE-led cuts continue to rock the federal government, we hear from National Parks employees about what’s at stake for visitors and wildlife, as well as the threat to the preservation of the history behind public lands.Guests: Andria Townsend & Helen DhueHave a tip or question about the new Trump administration? Call us at 202-240-2895. Learn more about your ad choices. Visit podcastchoices.com/adchoices

As federal agents detain a growing number of international college students, some are wondering: where are they getting these names? We hear about pro-Israel groups working to reveal details about student activists and how it could chill free speech.Guests: Gloria Pazmino, CNN CorrespondentHave a tip or question about the new Trump administration? Call us at 202-240-2895. Learn more about your ad choices. Visit podcastchoices.com/adchoices