Podcast Notes Playlist: Signal From The Noise: By Podcast Notes

Podcast Notes
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Mar 17, 2023 • 0sec

Trae Stephens - Find Good Quests - [Invest Like the Best, EP.319]

Invest Like the Best: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- My guest this week is Trae Stephens. Trae is a partner at Founders Fund and co-founder and Executive Chairman of Anduril. Trae’s philosophy can be boiled down to finding good quests, which has led him to investing in businesses that work closely with the government on societally important issues. Clearly, that extends to co-founding Anduril and I would highly recommend listening to my Business Breakdowns episode on Anduril if you haven’t already. In this conversation, we discuss the importance of lobbyists, why the high-tech defense firms of the past became stale, and how he hunts for disagreeableness in founders. Please enjoy my conversation with Trae Stephens.   For the full show notes, transcript, and links to mentioned content, check out the episode page here.   Listen to Founders Podcast Founders Episode 136 - Estee Lauder Founders Episode 288 - Ralph Lauren   -----   This episode is brought to you by Tegus, the modern research platform for leading investors. I’m a longtime user and advocate of Tegus, a company that I’ve been so consistently impressed with that last fall my firm, Positive Sum, invested $20M to support Tegus’ mission to expand its product ecosystem. Whether it’s quantitative analysis, company disclosures, management presentations, earnings calls - Tegus has tools for every step of your investment research. They even have over 4000 fully driveable financial models. Tegus’ maniacal focus on quality, as well as its depth, breadth and recency of content makes it the one-stop, end-to-end research platform for investors. Move faster, gather deep research to build conviction and surface high-quality, alpha-driving insights to find your differentiated edge with Tegus. As a listener, you can take the Tegus platform for a free test drive by visiting tegus.co/patrick.   -----   Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.    Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more.   Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here.   Follow us on Twitter: @patrick_oshag | @JoinColossus   Show Notes [00:03:17] - [First question] - Why Trae thinks most high-margin businesses are bad for society [00:04:28] - What would he change to impact energy technology most if he were in charge [00:06:18] - His investing focus on dynamism and mission-driven tech companies [00:09:42] - Analyzing why relatively few people strive to make society-level advancements [00:11:35] - What he’s done as a parent to enable his kids to develop passions [00:12:41] - The most noteworthy adventures in his career [00:14:41] - Founding Anduril and what it taught him about the tech industry [00:18:40] - The cutting-edge of defense technologies today [00:21:29] - What Shyam Sankar of Palantir taught him about defense tech [00:23:34] - Why some of the biggest defense tech companies have stopped innovating [00:28:29] - What he and Anduril have learned about sales and scaling in the public sector [00:32:12] - Where lobbyists and decision makers play in to defense tech business models [00:35:22] - His take on Peter Thiel’s notion that competition should be avoided [00:38:24] - The importance of being psychologically disagreeable when building a start-up [00:39:54] - The origin story that stands out the most from companies he has interviewed [00:41:12] - How he developed an investor mindset on his unorthodox path to the venture world [00:43:57] - What he has learned from playing supporting roles and aligning with great leaders [00:46:11] - Important but uncommon lessons about entrepreneurship [00:48:21] - Venture investing lessons he’s learned from Lauren Gross [00:50:00] - His first VR project and aspirations for the future of VR [00:54:50] - The role of religion and spirituality in his business philosophies [00:59:13] - Why he tries to capitalize on morality as opposed to sin [01:03:57] - The kindest thing anyone has ever done for him
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Mar 17, 2023 • 0sec

517: David Lieberman - How To Never Be Lied To Again, Decipher What People Really Think, What They Really Want, & Who They Really Are (Mind Reader)

Learning Leader Show: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Text Hawk to 66866 to become part of "Mindful Monday." Join 10's of thousands of your fellow learning leaders and receive a carefully curated email from me each Monday morning to help you start your week off right... Full show notes at www.LearningLeader.com Twitter/IG: @RyanHawk12   https://twitter.com/RyanHawk12 David Lieberman, Ph.D., is a renowned psychotherapist and the author of eleven books, including the New York Times bestsellers Get Anyone to Do Anything and Never Be Lied to Again. He has trained personnel in the U.S.  Ralph Waldo Emerson wrote: “People do not seem to realize that their opinion of the world is also a confession of character.” A person looks at the world as a reflection of themselves. If they see the world as corrupt, they feel on some level that they are corrupt. If they see honest working people, that is frequently how they see themselves. “How someone treats you is a reflection of their own emotional health and says everything about them and nothing about you.” Speaking negatively behind someone’s back orients you to look for the negative in others. Wouldn’t we rather spend time with people who seek the greatness in others? “The less emotionally healthy a person is, the more they denigrate the world to accommodate their own insecurities.” Knowledge is not power. Knowledge is a tool. How it is wielded makes all of the difference. Real power is the responsible application of knowledge. Word usage: Let’s take the example of giving a compliment. A woman who believes what she’s saying is more likely to use a personal pronoun. For instance, “I really liked your presentation.” However, a person offering insincere flattery might say, “Nice presentation,” or “Looks like you did a lot of research.” In the second case, she has removed herself from the equation. The Art of reading the bluff - When a person is bluffing, they are managing others’ impressions to convey the “right” effect and serve a personal agenda. Conversely, the authentic person is not interested in how they come across because they are unconcerned with their image. “People who bluff habitually overcompensate, so you can uncover a bluff instantly by noticing how someone tries to appear.” Relationships: Whenever David speaks to couples, he's always on the lookout when the word we is conspicuously absent from the conversation. We are attracted to positivity. It reflects humility. "Humility connects you to the ownership of mistakes." Humility can recognize a weakness in self. The difference between a sociopath and a psychopath: A sociopath has no conscious. They are very dangerous. A psychopath's wiring is off. They were born that way. Life and career advice: Find a passion that contributes to the world. Don't get too caught up in image or ego. "You can be anything. you're good at. as long as they're hiring." -- Chris Rock
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Mar 16, 2023 • 0sec

538: The Dalai Lama’s Guide to Happiness | Part 1

Ten Percent Happier with Dan Harris: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Dan flies to Dharamsala, India to spend two weeks in the orbit of His Holiness the Dalai Lama. This is the first installment of a five-part audio documentary series, something we’ve never done before now. Over the course of the episodes, we talk to His Holiness about practical strategies for thorny dilemmas, including: how to get along with difficult people; whether compassion can cut it in an often brutal world; why there is a self-interested case for not being a jerk; and how to create social connection in an era of disconnection. We also get rare insights from the Dalai Lama into everything from the mechanics of reincarnation to His Holiness’s own personal mediation practice. In this first installment, Dan watches as a young activist directly challenges His Holiness: In a world plagued by climate change, terrorism, and other existential threats, is the Dalia Lama’s message of compassion practical — or even relevant? Full Show Notes: https://www.tenpercent.com/podcast-episode/dalai-lama-guide-538Other Resources Mentioned:Healthy Minds InnovationsCompassionate Leadership SummitAdditional Resources:Download the Ten Percent Happier app today: https://10percenthappier.app.link/JoinChallengePodSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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Mar 16, 2023 • 0sec

#246 - AMA #45:  Pros and cons of GLP-1 weight loss drugs and metformin as a geroprotective agent

Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter In this “Ask Me Anything” (AMA) episode, Peter focuses the discussion on two topics getting a lot of attention recently. He first dives deep into GLP-1 agonists, most notably semaglutide and tirzepatide, which originally came to market as diabetes drugs but are now being studied and prescribed for weight loss. He walks through the data and compares the effectiveness of the two drugs, the side effects, and perhaps more importantly, his reservations around wide use of these drugs and who he would consider to be a candidate for them. Next, Peter discusses how metformin, another drug originally brought to market for diabetes management, gained popularity as a potential longevity drug even for non-diabetics. Peter gives his take on this possibility and reviews data from a more recent study investigating the question of whether metformin should be used for general “geroprotection.” If you’re not a subscriber and are listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #45 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: The hype around semaglutide, tirzepatide, and other GLP-1 agonists for weight loss [2:30]; Overview of GLP-1 agonists and why these drugs are getting so much attention [6:15]; Defining the term “geroprotective” [13:30]; Semaglutide: background, brand names, indications, and more [15:15]; Tirzepatide: background, brand names, indications, and more [19:15]; How semaglutide and tirzepatide compare in their efficacy in terms of weight loss and other metabolic health metrics [23:45]; Data showing sustained weight loss and improved metabolic metrics with after more than a year of using semaglutide and tirzepatide [29:00]; What happens to body weight when a patient discontinues the medication? [34:45]; Noteworthy side effects of GLP-1 agonists and similar classes of drugs [40:45]; Increased resting heart rate and other concerning trends in patients using GLP-1 agonists [45:15]; Changes in body composition (body fat and lean muscle) in patients on GLP-1 agonists [50:45]; Possible reasons for the loss of lean muscle mass and tips for protecting lean mass [59:00]; GLP-1 agonists and thyroid cancer [1:01:30]; Who might be a candidate for GLP-1 agonists? [1:03:45]; The large financial cost of this class of drugs [1:08:30]; Metformin as a geroprotective drug: origin of the idea that metformin could be a longevity agent even for non-diabetic patients [1:11:30]; A 2022 study on metformin sheds more light on the question of whether metformin should be used for “geroprotection” in non-diabetics [1:21:00]; Peter’s current approach with metformin for his patients [1:25:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
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Mar 16, 2023 • 0sec

Unlocking Creativity with Prompt Engineering | a16z Podcast with Steph Smith

A16z Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- With every new technology, some jobs are lost while others are gained. People often focus on the former, but in this episode we chose to highlight the latter – a highly creative role that emerges alongside AI: the prompt engineer.Until AI can close the loop of its own, each tool still requires a set of prompts. Just like a composer feeds an instrument the notes to play, a prompt engineer feeds an AI a map of what to produce. And if we know anything from music it’s that composing great music takes great skill!In this episode we explore the emerging importance of prompting with Guy Parsons, the early learnings of how to do it effectively, and where this field might be going.Will the prompt engineer be more like the highly sought after DevOps engineer, or a proficiency like Excel that you find on every resume? Listen in to hear Guy’s take.Interested in the prompt competition? Email us at podpitches@a16z.com.Resources:DALL-E 2 Prompt Book: https://dallery.gallery/the-dalle-2-prompt-book/Find Guy on Twitter: https://twitter.com/GuyPGuy’s combining image experiment: https://twitter.com/GuyP/status/1612880405207580672Guy’s amorphous prompt experiment: https://twitter.com/GuyP/status/1608475973300948993Guy’s space duck: https://twitter.com/GuyP/status/1601342688225525761Prompt base: https://promptbase.com/Lexica: https://lexica.art/ Topics Covered: 0:00 - Introduction01:49 - DALL-E 2 Prompt Book05:29 - Parallel skills06:51 - 80/20 prompting10:16 - New ways of prompting13:44 - Pulling the AI slot machine18:09 - Comparing models21:04 - Requested features26:34 - Learning with AI27:58 - Practical use cases32:08 - A top 1% prompt engineer36:17 - The most popular images Stay Updated: Find us on Twitter: https://twitter.com/a16zFind us on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://twitter.com/stephsmithioPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.
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Mar 16, 2023 • 0sec

The Fitness Supplements That Actually Work

Art of Manliness: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- In your journey towards becoming stronger, fitter, and healthier, there often comes a point where you wonder if taking some supplements will help your progress along. But what fitness supplements are actually effective and worth investing in?Here to answer that question is Layne Norton, a powerlifter and doctor of nutritional science who has a passion for debunking health-related myths and promoting evidence-based recommendations. He’s also, full disclosure, the owner of a supplement company himself. But I don’t have any financial connection to Layne’s company and we keep this conversation neutral and high-level. In our conversation, Layne argues that there are three top-tier research-backed supplements to consider — whey protein, creatine, and caffeine — and we unpack how to use each of them for optimal results. We discuss whether plant proteins are sufficient for building muscle, whether it’s true that creatine causes bloating, acne, and hair loss, how to best time your caffeine intake to energize your workouts, and much more. At the end of our conversation, Layne shares some additional supplements that seem promising for enhancing your health and fitness.Resources Related to the EpisodeLayne’s previous appearance on the AoM podcast: Episode #475 — How to Lose Weight, and Keep It Off ForeverLayne’s supplement company: Outwork NutritionAoM Article: A Primer On Muscle-Building Supplements — Which Work and Which Don’t?AoM Article: Creatine — A Primer on Its Benefits and UseAoM Article: How to Use Caffeine to Optimize Your WorkoutsAoM Article: Chugging Your Protein — It’s Whey Easier Than You ThinkAoM Podcast #285: The Real Science of Nutrition and SupplementsConnect With Layne NortonLayne on InstagramLayne‘s website
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Mar 13, 2023 • 0sec

Top Marathoner, Ken Rideout, On Making Money, Dealing With Addiction, And Mental Toughness

My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Episode 427: Sam Parr (@TheSamParr) and Shaan Puri (@ShaanVP) speak to Ken Rideout (@KenRideout_), one of the world's best masters runners, successful businessmen and entrepreneur. Ken talks about how he overcame addiction, built a lucrative career, forged mental and physical toughness, and where that's going to take him in the years to come. Want to see more MFM? Subscribe to the MFM YouTube channel here. SHAAN'S NEW DAILY NEWSLETTER --> shaanpuri.com ----- Links: * Teddy Atlas Podcast * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. ------ Show Notes: (00:23) - Why Ken is blowing up (12:25) - His finance background (23:45) - Ken's Struggles with Addiction (25:40) - How he got into running/media (31:25) - Who are the toughest people you have met? (38:20) - How to deal with adversity (41:50) - Story of Ken talking smack to Lance Armstrong (44:30) - How does he make money? (53:35) - Does this level of activity increase longevity? ----- Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more. ----- Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto * #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett • ​​​​#218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
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Mar 6, 2023 • 0sec

EP 36 - Marc Andreessen and Steven Sinofsky Talk Sentience, Ethics, Job Impacts, and the Future of AI

Aarthi and Sriram's Good Time Show ✓ Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- In this episode, the gang gets back together! Marc Andreessen and Steven Sinofsky are back to talk about all things AI. We cover the rise of ChatGPT, Bing's AI powered chat Sydney, AI ethics, sentience, whether AI will take over jobs, the economic impact, AI startups vs tech incumbents, and whether it is time for AI to become sentient. This was an incredibly fun episode! Marc Andreessen is an American entrepreneur, venture capital investor, and software engineer. He is the co-author of Mosaic, the first widely used web browser; co-founder of Netscape; and co-founder and general partner of Silicon Valley venture capital firm Andreessen Horowitz. Steven Jay Sinofsky is a former president of the Windows Division at Microsoft. He was responsible for the development and marketing of Windows, Internet Explorer, and online services such as Outlook.com and SkyDrive.
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Mar 3, 2023 • 0sec

Why Live? with Céline Leboeuf

Overthink ✓ Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- To be or not to be? That is the question. At the center of Hamlet’s soliloquy is the issue of whether life is worth living. In episode 72 of Overthink, Ellie and David consider this issue with philosopher and existentialism expert Céline Leboeuf. How can we find meaning in our lives when the world seems random and indifferent to our interests? Leboeuf talks about how her personal experience with an existential crisis and her philosophical search for a way out of it led her to consider religious, atheist, and spiritual answers to the question "Why Live?" Ellie and David also consider Camus’ notion of the absurd, and whether life is just a series of blips of suffering with no higher purpose.Works Discussed Albert Camus, The Myth of Sisyphus William James, “Is Life Worth Living”Céline Leboeuf, "Why Live? The Three Authors Who Saved Me During an Existential Crisis"John Jay McDermott “Why Bother: Is Life Worth Living?”Samuel Scheffer, Death and the AfterlifeLeo Tolstoy,  A Confession Support the showPatreon | patreon.com/overthinkpodcast Website | overthinkpodcast.comInstagram & Twitter | @overthink_podEmail | dearoverthink@gmail.comYouTube | Overthink podcast
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Mar 3, 2023 • 0sec

#160 TKP Insights: Leadership

Knowledge Project: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- In the third installment in a series of episodes, The Knowledge Project curates essential segments from five guests revolving around one theme: leadership. This episode helps put a unique definition on leadership and examines whether or not good leaders are context-dependent, the differences between a great leader and an average leader, how great leaders should balance feedback, the difference between being right and doing right, a playbook for managing teams, and the importance of radical candor. The guests on this episode are author Jim Collins (Episode 61, 110), author and leadership expert Jennifer Garvey Berger (Episode 43), co-founder of the Admired Leadership Institute Randall Stutman (Episode 96), the President and COO of Athletic Greens Kat Cole (Episode 117), the former CEO of Ford Alan Mulally (Episode 151), and co-founder of the Conscious Leadership Group Diana Chapman (Episode 130).   -- Want even more? Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/ Every Sunday our Brain Food newsletter shares timeless insights and ideas that you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/ Follow Shane on Twitter at: https://twitter.com/ShaneAParrish Our Sponsors: MetaLab: Helping the world’s top companies design, build, and ship amazing products and services. https://www.metalab.com Aeropress: Press your perfect cup, every time. https://aeropress.com

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