Clinician's Roundtable

Host: Ryan Quigley Neonatal food protein-induced enterocolitis syndrome (N-FPIES) is an underrecognized condition often misdiagnosed as necrotizing enterocolitis, despite distinct clinical and lab features that demand a different treatment approach. In this AudioAbstract, ReachMD's Ryan Quigley explores the early signs, immune pathways, and diagnostic markers of N-FPIES, offering essential insights to help pediatric clinicians identify this condition and initiate appropriate dietary management to avoid unnecessary interventions.

Guest: Laura B. Enyedi, MD Pediatricians are often the first to encounter eye conditions that can range from common to life-threatening. Hear from Dr. Laura Enyedi as she shares highlights from her presentation on diagnosing childhood ocular disorders from the 2025 American Academy of Pediatrics (AAP) National Conference and Exhibition. Dr. Enyedi is a Professor of Ophthalmology and an Associate Professor in Pediatrics at Duke University School of Medicine in Durham, North Carolina.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Jonathan Barratt, MD, PhD Delayed diagnosis and limited treatment options have historically been barriers to optimal management of IgA nephropathy (IgAN), but that paradigm may be shifting. A paper published in Kidney International in April 2025 points out that significant nephron loss often occurs before diagnosis, making early, targeted treatment essential. The paper makes the case for lowering proteinuria thresholds, minimizing steroid use, and employing safer, more effective therapies in combination. Joining Dr. Charles Turck to discuss this developing approach to IgAN care is Dr. Jonathan Barratt, the Mayor Professor of Renal Medicine at the University of Leicester in the UK and a coauthor of the study.Reference: Floege J, Bernier-Jean A, Barratt J, Rovin B. Treatment of patients with IgA nephropathy: a call for a new paradigm. Kidney International. 2025;S0085-2538(25)00076-6.

Host: Gates B. Colbert, MD Guest: Abdallah Geara, MD IgA nephropathy (IgAN) has a decades-long progression that requires careful monitoring of key biomarkers to optimize management. Hematuria, proteinuria, and estimated glomerular filtration rate levels are all critical to tracking the progression of the disease, and understanding how they’re connected can not only improve prognostication but also guide earlier, more targeted interventions to preserve kidney function. Joining Dr. Gates Colbert to walk through these markers and their importance is Dr. Abdallah Geara. He's an Associate Professor of Clinical Medicine, Clinical Director of the Glomerular Diseases Program, and the Director of Onconephrology at Penn Medicine in Philadelphia.

Host: Gates B. Colbert, MD Guest: Abdallah Geara, MD Guest: Ellie Kelepouris, MD, FACP, FAHA IgA nephropathy (IgAN) presents with a wide range of clinical signs, making timely detection and coordinated care essential. This multidisciplinary approach to diagnosis and management can manifest in a number of ways, from clinical evaluation and laboratory testing to emerging biomarkers and evolving treatment options. Joining Dr. Gates Colbert to discuss how we can use these strategies to optimize IgAN care are Drs. Abdallah Geara and Ellie Kelepouris. Dr. Geara is an Associate Professor of Clinical Medicine, the Clinical Director of the Glomerular Diseases Program, and Director of Onconephrology at Penn Medicine in Philadelphia, and Dr. Kelepouris is a Professor of Clinical Medicine, the Vice Chief of Clinical Affairs, and the Medical Director of Outpatient Dialysis Programs at Penn Medicine.

Guest: Jessica Snowden, MD, MS, FAAP, MHPTT Every moment counts when meningitis is suspected. To help reduce the risk of poor neurologic outcomes, Dr. Jessica Snowden is here to review age-based considerations that guide empiric antibiotic and antiviral choices—from neonatal infections acquired at delivery to risks in unvaccinated older children. Dr. Snowden is a Professor of Pediatrics and Vice Chancellor for Research at the University of Tennessee.

Guest: Jessica Snowden, MD, MS, FAAP, MHPTT Despite the success of meningitis vaccination programs, pediatricians must remain vigilant as cases still occur and can be life-threatening if missed. That’s why Dr. Jessica Snowden joins us to share how we can identify subtle behavioral cues, understand age-specific presentations, and diagnose patients using the gold-standard approach of lumbar puncture and CSF analysis. Dr. Snowden is a Professor of Pediatrics and Vice Chancellor for Research at the University of Tennessee.

Guest: Joe K. Tung, MD, MBA For dermatologists, treating psoriasis patients who use e-cigarettes can be challenging, particularly because of a lack of education about its risks, mental health concerns, and impacts on treatment efficacy. That being said, there are ways to address these challenges to support patients and improve outcomes. Join Dr. Joe Tung, a board-certified dermatologist who currently serves as the Medical Director of UPMC Falk Dermatology, Director of the Clinical Trials Unit, and Associate Director of the Dermatology Residency Program, as he discusses these barriers and potential solutions.

Guest: Joe K. Tung, MD, MBA While cigarette smoking is known to be linked to psoriasis, it was unclear whether or not e-cigarette use also carries risk. To address this research gap, a recent study analyzed data from over 28,000 United States adults, and, after adjusting for potential confounding variables, found that there is a statistically significant association between e-cigarette use and psoriasis. Hear Dr. Joe Tung, a coauthor of the study, break down its design and results, as well as potential reasons for this connection. Dr. Tung is a board-certified dermatologist who currently serves as the Medical Director of UPMC Falk Dermatology, Director of the Clinical Trials Unit, and Associate Director of the Dermatology Residency Program.

Guest: Aasma Shaukat, MD, MPH As fecal immunochemical testing (FIT) becomes more common in colorectal cancer screening, questions remain about post-FIT follow-up, especially when colonoscopies yield negative results. To explore this further, a recent review looked at the risk of colorectal cancer postcolonoscopy and analyzed the most common reasons it may occur. Hear Dr. Aasma Shaukat, a coauthor of the review, discuss the rationale behind it and its findings, which highlighted the importance of colonoscopy quality. Dr. Shaukat is the Robert M. and Mary H. Glickman Professor of Medicine and a Professor in the Department of Population Health at NYU Grossman School of Medicine. She also serves as the Director of Outcomes Research in the Division of Gastroenterology and Hepatology at NYU Langone Health.