NYU Langone Insights on Psychiatry

Starting this fall, we're releasing 12 more conversations with the best minds in psychiatry. Subscribe wherever you're listening, so you won't miss an episode.Visit our website for more Insights on Psychiatry.Watch this episode on YouTubeExecutive Producer: Jon Earle

Dr. Carla Nasca is an Assistant Professor in the Department of Psychiatry and the Department of Neuroscience and Physiology at NYU Langone, where she studies epigenetic mechanisms of neuroplasticity to stress. Dr. Nasca's work led to the discovery of acetyl-L-carnitine (LAC), a metabolite found in the mitochondria, as a promising biological marker of depression.Topics:acetyl-L-carnitine (LAC) and major depressive disorderHow stress changes the brain on a structural/molecular levelRisk factors for stress-induced disordersMachine learningMore information: https://www.cdr.rfmh.org/research/nasca-lab/Visit our website for more Insights on Psychiatry.Watch this episode on YouTubeExecutive Producer: Jon Earle

Dr. Tanya Sippy is an Assistant Professor in the Department of Psychiatry and the Department of Neuroscience and Physiology at NYU Langone. She’s also Principal Investigator at the Sippy Lab and Associate Director of the Psychedelic Medicine Research Training Program. Her research explores the neural mechanisms that underlie how sensory stimuli become associated with goal-directed behavior. Topics:How learning changes sensory representation (with implications for understanding addiction, etc.)Recent research on the functions of dopamine and serotoninHype vs reality of psychedelicsRegulation of ketamine clinics More information: https://www.sippylab.com/Visit our website for more Insights on Psychiatry.Watch this episode on YouTubeExecutive Producer: Jon Earle

Dr. Andrew Nierenberg is a Professor of Psychiatry at Harvard Medical School and Director of the MGH Dauten Family Center for Bipolar Treatment Innovation. He completed his residency in psychiatry at New York University/Bellevue Hospital.Topics:Lithium vs antipsychoticsSMART BD (Sequential Multiple Assignment of Randomized Treatment)Bipolar Learning Health NetworkMedication concordanceMore information:https://brain.harvard.edu/?people=andrew-nierenbergVisit our website for more Insights on Psychiatry.Watch this episode on YouTubeExecutive Producer: Jon Earle

Dr. Alan Schatzberg is a Professor of Psychiatry and Behavioral Sciences at Stanford Medicine, and Director of the Stanford Mood Disorders Center. His research examines the biology and psychopharmacology of depressive disorders. An NYU School of Medicine alumnus, Dr. Schatzberg was President of the American Psychiatric Association from 2009-2010.Topics:Ketamine and Esketamine (incl. mechanisms of action)Ketamine and obsessive-compulsive disorderOpioidsPsychedelic medicineFor more information:https://med.stanford.edu/profiles/alan-schatzbergVisit our website for more Insights on Psychiatry.Watch this episode on YouTubeExecutive Producer: Jon Earle

Dr. Michael Bogenschutz is a Professor of Psychiatry at the NYU Grossman School of Medicine, and Director of the NYU Langone Center for Psychedelic Medicine.Topics:Psilocybin-assisted psychotherapy for alcohol use disorderMDMA-assisted psychotherapy for PTSDPsychedelic medicine for the "worried well"The role of the mystical experienceComparing different psychedelic medicinesMechanisms of actionTreatment protocolsSafety and risk-mitigationTopics for further investigationCited:Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder (August 2022)For more information:https://centerforpsychedelicmedicine.org/Visit our website for more Insights on Psychiatry.Watch this episode on YouTubeExecutive Producer: Jon Earle

Dr. Omonigho M. Bubu is an Assistant Professor of Psychiatry and Population Health at the NYU Grossman School of Medicine, where he studies the connection between sleep and neurodegenerative diseases, as well as social determinants of health as they relate to cognitive health. In this interview, he discusses the importance of sleep, especially for people at higher risk of developing Alzheimer’s disease.Topics:Alzheimer’s disease (AD)Associations between sleep and increased AD riskSleep patterns in minoritized communitiesObstructive sleep apneaDementia and cognitive declineSocial determinants of healthCited:Obstructive sleep apnea, cognition and Alzheimer's disease: A systematic review integrating three decades of multidisciplinary research (2020)Sleep, Cognitive impairment, and Alzheimer’s disease: A Systematic Review and Meta-Analysis (2016)Visit our website for more information:https://physicianfocus.nyulangone.org/nyu-langone-insights-on-psychiatry-podcast/Visit our website for more Insights on Psychiatry.Watch this episode on YouTubeExecutive Producer: Jon Earle

Naomi Simon, MD, talks about her research into mindfulness-based stress reduction (MBSR) and yoga as treatments for anxiety disorders. Dr. Simon is a Professor in the Department of Psychiatry at the NYU Grossman School of Medicine, and Director of the Anxiety, Stress, and Prolonged Grief Program.Topics:Generalized Anxiety Disorder (GAD)Mindfulness-Based Stress Reduction (MBSR)Kundalini yogaSelective serotonin reuptake inhibitors (SSRIs)Access to MBSR & Yoga (including smartphone apps)Cognitive behavioral therapy (CBT)ExerciseMechanism(s) of actionCited: Mindfulness-Based Stress Reduction vs Escitalopram for the Treatment of Adults With Anxiety Disorders (Nov. 2022)Visit our website for more Insights on Psychiatry.Watch this episode on YouTubeExecutive Producer: Jon Earle

Mohammed Milad, PhD, discusses recent research into fear conditioning, regulation, and extinction. Dr. Milad is a Professor in the Department of Psychiatry at the NYU Grossman School of Medicine and Director of the Behavioral Neuroscience Program.Topics covered:Transcranial magnetic stimulation (TMS)Estrogen and PTSDPost-traumatic stress disorder (PTSD)MeditationDeep brain stimulationVisit our website for more Insights on Psychiatry.Watch this episode on YouTubeExecutive Producer: Jon Earle

Ayana Jordan, MD, PhD, is the Barbara Wilson Associate Professor of Psychiatry at the NYU Grossman School of Medicine, an Associate Professor in the Department of Population Health, and the Pillar Lead for the Institute for Excellence in Health Equity.Topics covered:Lack of improvement in health equity nationwideAdvice for clinicians on providing equitable careStructural competence vs. cultural competenceThoughts on integrating alternative therapies (ex. acupuncture, spirituality)Using data to improve health equityVisit our website for more Insights on Psychiatry.Watch this episode on YouTubeExecutive Producer: Jon Earle