The Longevity & Lifestyle Podcast

Claudia von Boeselager
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Dec 4, 2025 • 52min

#230 The Future of Health Optimization: Diagnostics, Stem Cells & Scaling Longevity for Everyone With Jim Donnelly

What if health optimization wasn’t just for the elite — but something every teacher, firefighter, and family could access?In this inspiring episode, Jim Donnelly, founder and CEO of Humanaut Health (and former founder of Restore Hyper Wellness), shares how he’s building the most comprehensive, prevention-driven longevity model to date. From advanced diagnostics and regenerative medicine to behavior change and coaching, Jim reveals what it truly takes to add 10–20 healthy, vibrant years to life.He opens up about the loss of his father, surviving a near-fatal car accident, and how stem cell therapy transformed his recovery — all of which shaped his mission to scale health optimization with integrity, accessibility, and world-class medical excellence.We explore:Why foundational habits (sleep, movement, nutrition, stress) drive 90% of resultsHow Humanaut uses 150+ diagnostics to find root causesWhy regenerative medicine works best on a healthy foundationHow to democratize longevity without sacrificing qualityWhat it takes to reverse metabolic dysfunction — 86% success in under 6 monthsThis conversation is a powerful reminder that the future of medicine is preventive, personalized, and incredibly hopeful.Tune in and discover what’s possible when we invest in health — not after we’re sick, but while we’re thriving.Support this podcast at — https://redcircle.com/the-longevity-and-lifestyle-podcast/donations
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Nov 27, 2025 • 29min

#229 Movement, Pain & Red Light Therapy: The New Longevity Equation with Forrest Smith of Kineon

Pain might feel like an inevitable part of aging — but what if it’s actually fixable?In this episode, Forrest Smith, CEO and co-founder of Kineon, unpacks the cutting-edge science behind red light and laser therapy, why inflammation is the real driver of pain and accelerated aging, and how daily, targeted phototherapy can transform mobility, energy, and long-term health.We explore the link between inflammation and chronic disease, the surprising gut–brain–thyroid connection, and why repairing internal tissue with the right light wavelengths can dramatically shift your health trajectory.We cover:The four pillars of red light therapy at the cellular levelWhy treating inflammation is key to longevity and mobilityHow gut health, thyroid function & brain health connect through lightRed light protocols for pain relief, energy, mood & recoveryHow Kineon’s Move+ Pro is disrupting traditional pain managementIf you want to stay active, mobile, and pain-free for life, this conversation is a must-listen.Tune in and learn how to use light to heal your body from the inside out.Support this podcast at — https://redcircle.com/the-longevity-and-lifestyle-podcast/donations
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Nov 21, 2025 • 53min

#228 JJ Virgin — On Muscle Is the New Longevity: The Science of Strength, Aging & Metabolism

When it comes to longevity, your gut might hold the master key. In this fascinating episode, Colleen Cutcliffe, PhD, CEO and co-founder of Pendulum Therapeutics, reveals how a single gut bacterium—Akkermansia muciniphila—is transforming the future of metabolic and hormonal health.From her daughter’s early health challenges to pioneering live Akkermansia in supplement form, Colleen shares her journey from biotech to natural therapeutics. Discover how the microbiome impacts metabolism, energy, brain function, menopause, and even GLP-1 hormone production—the same pathway drugs like Ozempic mimic.We explore:Why 88% of Americans are metabolically unhealthyThe gut’s role as the root system of longevityHow Akkermansia acts as “the glue” for gut lining integrityThe connection between gut bacteria and women’s hormonesBreakthroughs in microbiome-based therapies and “bugs as drugs”Whether you’re curious about reversing metabolic dysfunction or optimizing your healthspan naturally, this episode is your deep dive into the science and soul of gut health.Sponsors: Carol Bike: Get $300 off from Oct 17 – Dec 26, 2025, with code CLAUDIA, and enjoy an ongoing $100 off afterward. Visit carolbike.com/claudia and use code CLAUDIA at checkout.Pendulum: Get 20% off your first membership order at pendulumlife.com/CLAUDIA20, your discount applies automatically.Juvent: Get $300 off the Juvent Micro-Impact Platform at juvent.com/CLAUDIA and check out with code CLAUDIA.Kineon: Get 10% off your MOVE+ Pro at kineon.io/claudiaCalocurb: Get 10% off at calocurb.com/longevityandlifestyle with code CLAUDIA10 at checkout.Support this podcast at — https://redcircle.com/the-longevity-and-lifestyle-podcast/donations
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Nov 12, 2025 • 48min

#227 The Gut-Longevity Connection: How Pendulum’s Live Akkermansia Is Revolutionizing Metabolic Health - Dr. Colleen Cutcliffe

When it comes to longevity, your gut might hold the master key. In this fascinating episode, Colleen Cutcliffe, PhD, CEO and co-founder of Pendulum Therapeutics, reveals how a single gut bacteriu, Akkermansia muciniphila - is transforming the future of metabolic and hormonal health.From her daughter’s early health challenges to pioneering live Akkermansia in supplement form, Colleen shares her journey from biotech to natural therapeutics. Discover how the microbiome impacts metabolism, energy, brain function, menopause, and even GLP-1 hormone production—the same pathway drugs like Ozempic mimic.We explore:Why 88% of Americans are metabolically unhealthyThe gut’s role as the root system of longevityHow Akkermansia acts as “the glue” for gut lining integrityThe connection between gut bacteria and women’s hormonesBreakthroughs in microbiome-based therapies and “bugs as drugs”Whether you’re curious about reversing metabolic dysfunction or optimizing your healthspan naturally, this episode is your deep dive into the science and soul of gut health.This episode is brought to you by Pendulum - get 20% off your first membership order at pendulumlife.com/CLAUDIA20, your discount applies automatically.Support this podcast at — https://redcircle.com/the-longevity-and-lifestyle-podcast/donations
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Nov 7, 2025 • 34min

#226 Turning Back Time: The ROI of Health, Reversing Biological Age, Longevity & Purpose With Claudia von Boeselager

What’s the true return on investment when it comes to your health? In this special episode, Claudia joins Liz Bradford on the Health ROI Show to share how she reversed her biological age by 17 years, all while running multiple businesses and raising a family. Together, they unpack the data-driven strategies that deliver the biggest health ROI: from optimizing sleep and managing stress to rebalancing hormones and designing sustainable daily systems that work for high performers.You’ll learn:Why your “why” is the foundation of lasting transformationThe non-negotiables that drive real energy and focusHow to use data to personalize your health optimizationSimple, high-impact longevity habits anyone can start todayIf you’ve ever felt too busy to prioritize your health, this episode will shift your mindset — and your biology. Tune in to discover how to maximize your energy, longevity, and vitality, one smart investment at a time.Sponsors: Carol Bike: Get $300 off from Oct 17 – Dec 26, 2025, with code CLAUDIA, and enjoy an ongoing $100 off afterward. Visit carolbike.com/claudia and use code CLAUDIA at checkout.Pendulum: Get 20% off your first membership order at pendulumlife.com/CLAUDIA20, your discount applies automatically.Juvent: Get $300 off the Juvent Micro-Impact Platform at juvent.com/CLAUDIA and check out with code CLAUDIA.Kineon: Get 10% off your MOVE+ Pro at kineon.io/claudiaCalocurb: Get 10% off at calocurb.com/longevityandlifestyle with code CLAUDIA10 at checkout.Support this podcast at — https://redcircle.com/the-longevity-and-lifestyle-podcast/donations
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Nov 2, 2025 • 34min

#225 NASA’s Secret to Stronger Bones, Better Balance & Longevity With Spotify / Apple Title Peter Simonson - NASA’s Secret to Stronger Bones, Better Balance & Longevity

What if the secret to longevity wasn’t more movement but the right kind of movement?In this episode, Peter Simonson, President, Co-Founder, and Board Member of Juvent, reveals how NASA-backed micro-impact technology is transforming bone density, balance, and vitality from the ground up.We unpack the science of mechanotherapy, how gentle vibrations can stimulate bones and circulation, and why this “passive exercise” could be a game-changer for aging well — especially for those recovering from injury or struggling with mobility.We explore:The link between bone health and longevityHow NASA research inspired Juvent’s micro-impact platformThe surprising benefits for balance, circulation, and energyWhy strong bones equal longer, healthier livesSponsors: This episode is brought to you by Juvent, creators of the Micro-Impact Platform. A breakthrough technology that helps improve circulation, bone health, and reduce pain naturally. Just stand on it for 20 minutes a day and let gentle micro-impacts work at the cellular level to support healing and mobility. Get $300 off the Juvent Micro-Impact Platform at juvent.com/CLAUDIA with code CLAUDIASupport this podcast at — https://redcircle.com/the-longevity-and-lifestyle-podcast/donations
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Oct 24, 2025 • 54min

#224 Dr. Chris Shade: How to Remove Toxins, Boost Glutathione & Reverse Cellular Aging

Are Hidden Toxins Silently Aging You From the Inside Out?Brain fog. Fatigue. Anxiety. Hormonal chaos.For millions, these symptoms aren’t just “stress” — they’re signs of toxic overload.In this episode, Dr. Chris Shade, founder of Quicksilver Scientific and one of the world’s leading experts on mercury and detoxification, reveals how environmental toxins, heavy metals, and everyday exposures are quietly disrupting your mitochondria, hormones, and brain — and what you can do to reverse it.This isn’t another “detox fad.” It’s cutting-edge biochemistry meets practical longevity science — from the man who helped Tony Robbins recover from severe mercury toxicity.Dr. Shade shares how to safely clear toxins, repair your mitochondria, and reignite your body’s natural longevity systems — without wrecking your energy in the process.Together, we explore:◼️ The truth about mercury, heavy metals & how they destroy energy and focus◼️ The link between toxins, inflammation, and accelerated aging◼️ Glutathione: the “master antioxidant” and anti-aging molecule explained◼️ How stress blocks detox pathways and why calm equals longevity◼️ The 3-step detox process: Drain, Move, Bind — and how to do it safely◼️ Practical daily habits to support liver, bile, and mitochondrial health◼️ The role of peptides, saunas, and bitters in next-generation detox protocolsThis Episode was brought to you by:Juvent: Get $300 off the Juvent Micro-Impact Platform at juvent.com/CLAUDIA with code CLAUDIA.Pendulum: Get 20% off your first membership order with Pendulum at pendulumlife.com/CLAUDIA20Carol Bike: Get $300 off from CarokBike, from Oct 17 – Dec 26, 2025, with code CLAUDIA, and enjoy an ongoing $100 off afterward. Visit carolbike.com and use code CLAUDIA at checkout.Support this podcast at — https://redcircle.com/the-longevity-and-lifestyle-podcast/donations
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Oct 17, 2025 • 1h 15min

#223 — VO₂ Max and The Science Behind CAROL Bike: 8-Minute Workouts to Boost VO₂ Max, Metabolism & Longevity with Ulrich Dempfle

Can 8 Minutes Really Transform Your Fitness, Metabolism, and Longevity?We’ve been told we need hours of cardio each week to stay fit but what if the science says otherwise?In this episode, Ulrich Dempfl, co-founder and CEO of CAROL Bike, reveals how AI-powered workouts and REHIT (Reduced Exertion High-Intensity Training) are revolutionizing exercise by delivering maximum fitness results in minimum time.This isn’t another quick-fix fitness fad. It’s a data-driven, scientifically validated method backed by research from top universities — and it’s transforming how busy, high-performing people train, burn fat, and extend their healthspan.Ulrich Dempfl is a health tech innovator and the co-creator of the CAROL Bike, an AI exercise bike proven to dramatically improve VO₂ max, insulin sensitivity, and metabolic health all in under 9 minutes a day.Together, we discuss:◼️ The science behind REHIT — and how it differs from traditional HIIT◼️ Why just two 20-second sprints can trigger profound metabolic changes◼️ How CAROL Bike uses AI to personalize resistance and optimize results◼️ The link between short, intense workouts and longevity biomarkers◼️ How to reprogram your metabolism for fat loss and cardiovascular health◼️ The future of smart, efficient fitness in an AI-driven worldThis is a conversation that challenges everything you thought you knew about exercise, endurance, and time.Ready to train smarter, live longer, and reclaim your time?Tune in now to discover the 8-minute workout that’s redefining longevity.This episode is brought to you by CAROL Bike. CAROL isn’t just another stationary bike, it’s backed by published research and powered by AI-driven Reduced-Exertion HIIT (REHIT) to deliver the same cardio benefits as a 45-minute jog in under five minutes. Studies show CAROL can improve your VO₂max by 12% in just eight weeks, making you up to 10 years fitter. If you’re serious about optimizing your health and longevity, this is the smartest, most efficient workout you can do.Check it out at https://www.carolbike.com/claudia - get $300 off from October 17 to December 26, 2025, and afterwards enjoy an ongoing $100 discount with code CLAUDIA at checkout.Support this podcast at — https://redcircle.com/the-longevity-and-lifestyle-podcast/donations
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Oct 10, 2025 • 45min

#222 The Big Lies in Medicine: How to Reverse Disease, Slow Aging & Reclaim Your Health with Dr. Robert Lufkin

In this enlightening conversation, Dr. Robert Lufkin, a physician and bestselling author, shares his journey of reversing four chronic diseases through lifestyle changes. He challenges conventional medical beliefs, emphasizing that lifestyle—not just pills—can effectively combat chronic illness. Discussing metabolic health, he explores innovative topics like the benefits of rapamycin, psychedelics for brain health, and the importance of personal agency in healthcare. Dr. Lufkin reveals how we can all become CEOs of our own health, prioritizing choices for longevity and vitality.
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Oct 2, 2025 • 51min

#221 The Untapped Longevity Secret: How S€xual Wellness & Psychedelics Can Shape Your Healthspan with Dr. Dave Rabin, Ashley Madsen and Claudia von Boeselager

What if your sex life was the ultimate barometer of your health and longevity?In this episode, psychiatrist and neuroscientist Dr. Dave Rabin and precision medicine expert Ashley Madsen reveal the hidden connection between sexual wellness, hormones, the nervous system, and long-term vitality, plus how psychedelics may unlock deeper intimacy and healing.From midlife hormonal shifts and perimenopause to nervous system safety and relationship dynamics, we explore why pleasure isn’t just indulgence, it’s medicine for the body and brain.You’ll learn:Why sexual health predicts overall healthspan and resilienceThe surprising role of nervous system regulation in desire and arousalHow midlife hormonal changes affect libido, mood, and connectionPractical ways to cultivate safety, intimacy, and pleasure at any ageThe emerging role of psychedelics in healing relationships and traumaThis is a science-meets-soul conversation that reframes sexual wellness as a vital pillar of longevity and thriving at every stage of life.Ready to embrace pleasure as part of your health journey? Tune in nowSupport this podcast at — https://redcircle.com/the-longevity-and-lifestyle-podcast/donations

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