BlueDot Narrated

BlueDot Impact
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Dec 4, 2025 • 26min

The New Bioweapons: How Synthetic Biology Could Destabilize the World

Audio versions of blogs and papers from BlueDot courses.Original text: https://drive.google.com/file/d/19dxfYiUnrK4fR5EJW3Nb2zkpgvsEC28y/view?usp=sharingAuthor(s): Roger Brent, T. Greg McKelvey, Jr., and Jason MathenyA podcast by BlueDot Impact.
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Dec 4, 2025 • 32min

The Worst Covid Strategy Was Not Picking One

Audio versions of blogs and papers from BlueDot courses.Original text:https://www.bloomberg.com/graphics/2023-opinion-lessons-learned-from-covid-pandemic-global-comparison/Author(s):Bloomberg OpinionA podcast by BlueDot Impact.
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Dec 4, 2025 • 37min

Indoor Air Quality Is the Next Great Public Health Challenge

Audio versions of blogs and papers from BlueDot courses."Cleaner indoor air can increase productivity, improve student outcomes, and prevent pandemics."Original text: https://ifp.org/indoor-air-quality/Author(s): Juan Cambeiro and Brian PotterA podcast by BlueDot Impact.
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Dec 4, 2025 • 17min

Broad-Spectrum Antiviral Agents: A Crucial Pandemic Tool

Audio versions of blogs and papers from BlueDot courses.Original text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103698/Author(s): Amesh Adalja and Thomas InglesbyA podcast by BlueDot Impact.
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Dec 4, 2025 • 22min

ESM3: Simulating 500 Million Years of Evolution with a Language Model

Audio versions of blogs and papers from BlueDot courses.ESM3 is an AI model which is trained on protein sequence, structure and function data. This allows it to follow prompts to design novel proteins. When reading, consider the ways in which this model might present opportunities and risks for pandemic preparedness.Original text: https://www.evolutionaryscale.ai/blog/esm3-releaseAuthor(s): Evolutionary Scale blogA podcast by BlueDot Impact.
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Dec 4, 2025 • 23min

From Warp Speed to 100 Days

Audio versions of blogs and papers from BlueDot courses."During the COVID pandemic, we learned to design vaccines within weeks. Now, the bottleneck is testing that they work. To get even faster, we need innovations in clinical trial design."Original text: https://asteriskmag.com/issues/04/from-warp-speed-to-100-daysAuthor(s): Witold WięcekA podcast by BlueDot Impact.
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Dec 4, 2025 • 16min

Differential Technology Development: An Innovation Governance Consideration for Navigating Technology Risks

Audio versions of blogs and papers from BlueDot courses.This paper introduces a framing of "differential technology development" – affecting the relative timing of new innovations to reduce a specific risk. For instance, it may be beneficial to delay or halt risk-increasing technologies and preferentially advance risk-reducing defensive, safety, or substitute technologies. As you read, consider how you might apply this framing to biosecurity risks associated with developments in AI and biotechnology (this week's pre-class exercise).Original text: https://ora.ox.ac.uk/objects/uuid:b481e9ad-bc27-4550-87ca-f414354aeb35Author(s): Jonas B. Sandbrink, Hamish Hobbs, Jacob L. Swett, Allan Dafoe, Anders SandbergA podcast by BlueDot Impact.
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Dec 4, 2025 • 16min

A Framework for Technical Progress on Biosecurity

Audio versions of blogs and papers from BlueDot courses.In this post, Kyle Fish presents five key goals for biosecurity technologies: to be fast, general, cheap, robust, and scalable. These will be useful heuristics for us to apply as we consider a range of interventions over the next three weeks. Kyle was previously the CTO at Alvea, a vaccine start-up which became the fastest startup to take a new drug from founding to a Phase 1 clinical trial.Original text: https://forum.effectivealtruism.org/posts/rjFJYREBZZscvDwLu/a-framework-for-technical-progress-on-biosecurityAuthor(s): Kyle FishA podcast by BlueDot Impact.
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Dec 4, 2025 • 23min

Towards a Theory of Pandemic-Proof PPE

Audio versions of blogs and papers from BlueDot courses."Vital workers must be protected against viral threats so that critical functions of society can continue during a global pandemic. Globally, COVID-19 revealed weaknesses in the PPE enterprise including production and distribution limitations, counterfeit and poor-quality products, and inadequate stockpiles. End users struggled with design limitations that often reduced the level of protection they were afforded and made completing their work more difficult. Moreover, requirements for PPE that could protect against a future pandemic involving a feasible, worst-case pathogen were under-characterized. This study strives to identify strategies to improve the PPE ecosystem to prepare the world for the next pandemic by ensuring that vital workers have the PPE they need to perform their jobs safely."Original text: https://blueprintbiosecurity.org/u/2024/05/Towards-a-Theory-of-Pandemic-Proof-PPE-Blueprint.pdfAuthor(s): Blueprint Biosecurity and Gryphon ScientificA podcast by BlueDot Impact.
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Dec 4, 2025 • 31min

What Were the Death Tolls from Pandemics in History?

Audio versions of blogs and papers from BlueDot courses.This resource from 'Our World in Data' estimates the death tolls from the most devastating pandemics in history, with a particular focus on the 19th century onwards.Original text: https://ourworldindata.org/historical-pandemicsAuthor(s): Our World in DataA podcast by BlueDot Impact.

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