Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic, https://chrismasterjohnphd.com/paleovalley, https://chrismasterjohnphd.com/seekinghealth, https://chrismasterjohnphd.com/ancestralsupplements, https://chrismasterjohnphd.com/magicspoon, https://chrismasterjohnphd.com/lmnt Plenty more at https://chrismasterjohnphd.com/support! Question: How should you program the temperature on an Ooler or Eight Sleep?The way that I do it is, if I wake up feeling cold, I want to program it to increase the temperature at that time point so that I do not wake up cold. So, I would say, generally speaking, you want it as cold as it can be starting, that does not interfere with your sleep, and you want it as cold as can be in the middle of the night, that does not wake you up. So, I think that's going to be very different for each person, and I think whatever temperature prevents you from waking up cold, is the one you want. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice. Access the show notes, transcript, and comments here.

Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic, https://chrismasterjohnphd.com/paleovalley, https://chrismasterjohnphd.com/seekinghealth, https://chrismasterjohnphd.com/ancestralsupplements, https://chrismasterjohnphd.com/magicspoon, https://chrismasterjohnphd.com/lmnt Plenty more at https://chrismasterjohnphd.com/support! Question: Is it useful to measure HVA, VMA, and 5-HIAA?I find them useful in a very limited context. The limitation of their usefulness is basically that you can't really tell if something is high or low because of production or degradation. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice. Access the show notes, transcript, and comments here.

Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic, https://chrismasterjohnphd.com/paleovalley, https://chrismasterjohnphd.com/seekinghealth, https://chrismasterjohnphd.com/ancestralsupplements, https://chrismasterjohnphd.com/magicspoon, https://chrismasterjohnphd.com/lmnt Plenty more at https://chrismasterjohnphd.com/support! Question: What nutrients require insulin to get into cells?Magnesium phosphorus and potassium are the big ones that are going to have poor uptake in response to insulin. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice. Access the show notes, transcript, and comments here.

Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic, https://chrismasterjohnphd.com/paleovalley, https://chrismasterjohnphd.com/seekinghealth, https://chrismasterjohnphd.com/ancestralsupplements, https://chrismasterjohnphd.com/magicspoon, https://chrismasterjohnphd.com/lmnt Plenty more at https://chrismasterjohnphd.com/support! Question: What are the top whole food supplements to take?I mean, that's kind of too general a question, especially for end of the AMA rapid-fire. I don't make blanket supplements suggestions, but in the likes of Oystermax, an organ mix or liver supplement from Ancestral or from Paleovalley, although their organ mix is a sold out, and nutritional yeast, I think are great components of a natural, DIY, whole food multivitamin. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice. Access the show notes, transcript, and comments here.

Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic, https://chrismasterjohnphd.com/paleovalley, https://chrismasterjohnphd.com/seekinghealth, https://chrismasterjohnphd.com/ancestralsupplements, https://chrismasterjohnphd.com/magicspoon, https://chrismasterjohnphd.com/lmnt Plenty more at https://chrismasterjohnphd.com/support! Question: Could iron deficiency create a complex 1 disorder?If you're iron deficient and you have blood work that looks like a complex 1 block, and you feel like you have an energy metabolism disorder, then, while it is possible you have a genetic complex 1 deficiency, it's also possible you have an iron deficiency that is not playing out in your CBC or your thyroid panel that is impacting your energy metabolism. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice. Access the show notes, transcript, and comments here.

Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic, https://chrismasterjohnphd.com/paleovalley, https://chrismasterjohnphd.com/seekinghealth, https://chrismasterjohnphd.com/ancestralsupplements, https://chrismasterjohnphd.com/magicspoon, https://chrismasterjohnphd.com/lmnt Plenty more at https://chrismasterjohnphd.com/support! Question: How to get more sulfate if you have sulfite issues? If you're not converting sulfite to sulfate, that should be a molybdenum deficiency. If it's not a molybdenum deficiency it's probably a gut microbiota problem. Could be a sulfite oxidase enzyme deficiency, of course, but I think it would be much more common that you have sulfate metabolizing bacteria in the intestines, then that you have a sulfite oxidase genetic deficiency. Although, you can never rule out a modest impairment in that enzyme, that would not be diagnosed with anything. So, it can't be ruled out. But I do you think it's going to be much more common that someone has a sulfur intolerance that's driven by gut microbiota. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice. Access the show notes, transcript, and comments here.

Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic, https://chrismasterjohnphd.com/paleovalley, https://chrismasterjohnphd.com/seekinghealth, https://chrismasterjohnphd.com/ancestralsupplements, https://chrismasterjohnphd.com/magicspoon, https://chrismasterjohnphd.com/lmnt Plenty more at https://chrismasterjohnphd.com/support! Question: If you're eating oysters, do you need to eat liver too? And I think oysters are more reliably a source of zinc relative to copper and relative to liver. And liver is much more consistently a source of copper relative to zinc and relative to oysters. And so I stand by what I said in terms of taking into account the variation in different species of oyster, in different oceans and different batches of oyster products, but Oystermax does batch testing. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice. Access the show notes, transcript, and comments here.

Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic, https://chrismasterjohnphd.com/paleovalley, https://chrismasterjohnphd.com/seekinghealth, https://chrismasterjohnphd.com/ancestralsupplements, https://chrismasterjohnphd.com/magicspoon, https://chrismasterjohnphd.com/lmnt Plenty more at https://chrismasterjohnphd.com/support! Question: Lipoic acid: does it need to be the R form? Lipoic acid can help with blood sugar and it is an antioxidant. I would always use R-Lipoic acid. I would never use the racemic mixture of alpha-lipoic acid because the R form is the biologically active one. And I think it might be the case that you can just take a higher dose, but why mess around with the possibility that some isomer that doesn't belong in your body and isn't found in food, isn't going to interfere with the function of the R form. So I would just take R- Lipoic acid for any purpose at all. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice. Access the show notes, transcript, and comments here.

Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic, https://chrismasterjohnphd.com/paleovalley, https://chrismasterjohnphd.com/seekinghealth, https://chrismasterjohnphd.com/ancestralsupplements, https://chrismasterjohnphd.com/magicspoon, https://chrismasterjohnphd.com/lmnt Plenty more at https://chrismasterjohnphd.com/support! Question: How much fruit is it safe to eat at once? I don't really agree with that premise and that premise might be sensible at really high fructose intake, but I don't think many people are going to hit that by eating fruit, unless they're on a fruitarian diet. I think if you're eating 1, 2, 3 servings of fruit at a time, you're probably not going to seriously hit that mark, but that depends on your energy metabolism and the rest of your diet. So I think the metric to look at that would be your uric acid levels. If your uric acid levels are high, you are eating a lot of fruit at one sitting. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice. Access the show notes, transcript, and comments here.

Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic, https://chrismasterjohnphd.com/paleovalley, https://chrismasterjohnphd.com/seekinghealth, https://chrismasterjohnphd.com/ancestralsupplements, https://chrismasterjohnphd.com/magicspoon, https://chrismasterjohnphd.com/lmnt Plenty more at https://chrismasterjohnphd.com/support! Question: Should I supplement NAC if cysteine, taurine, and sulfate are low? You can supplement NAC, but you probably just need more animal protein. Although a vegan could supplement NAC instead of animal protein. If your homocysteine is on the high side, then you definitely want to increase methionine in order to increase SAMe to increase the breakdown of homocysteine. If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice. Access the show notes, transcript, and comments here.