ESC Cardio Talk

Paolo Springhetti, a Milanese cardiologist specializing in transcatheter valve therapies, joins Marie-Annick Clavel to discuss the LANDMARK trial findings. They dive into the unique sizing advantages of Myval compared to competitors, highlighting impressive hemodynamic outcomes. Sex-specific definitions of patient-prosthesis mismatch (PPM) come under scrutiny, revealing stark differences among valve types. The duo also explores the implications of Myval's low-flow recovery and durability concerns for younger patients, emphasizing the need for long-term studies.

With Domenico Filomena, Polyclinic Umberto I, Rome - Italy and Luciano Agati Sapienza, University of Rome, Rome - Italy. Link to European Heart Journal paper Link to European Heart Journal editorial

With Jonathan Lessick, Rambam Health Care Campus, Haifa - Israel and Mahmoud Suleiman, Rambam Health Care Campus, Haifa - Israel. Link to European Heart Journal paper Link to European Heart Journal editorial

With Maura Marcucci, Clinical Institute Humanitas IRCCS, Rozzano - Italy and McMaster University, Hamilton - Canada and Mauro Chiarito, Clinical Institute Humanitas IRCCS, Rozzano - Italy and Icahn School of Medicine at Mount Sinai, NYC - USA. Link to European Heart Journal paper Link to European Heart Journal editorial

With Jean-Benoit Le Polain de Waroux, St-Jan Hospital, Brugge - Belgium, and Maarten De Smet, AZ Sint Jan, Brugge - Belgium. Link to European Heart Journal paper Link to European Heart Journal editorial

Allan Sniderman, a cardiologist and professor at McGill University, dives into the importance of ApoB and Lp(a) for cardiovascular risk assessment. He challenges traditional views on VLDL versus LDL atherogenicity, revealing that VLDL may pose greater risks than previously thought. Sniderman discusses a comprehensive study involving over 200,000 participants, elaborating on how examining particle numbers can change risk interpretations. He advocates for measuring ApoB and Lp(a) to enhance clinical insights and streamline patient care.

With David Erlinge and Sasha Koul, Lund University, Lund - Sweden Read the European Heart Journal paper Read the European Heart Journal editorial

With Børge Nordestgaard and Anders Berg Wulff, Copenhagen University Hospital, Copenhagen - Denmark. Read the European Heart Journal - Cardiovascular Imaging paper Read the European Heart Journal - Cardiovascular Imaging editorial

With Edward Hulten, Brown University, Providence, and Islam Shatla, University of Kansas Medical Center, Kansas City, USA. Link to editorial Link to paper

With Francesca Coraducci Marche Polytechnic University of Ancona, Ancona - Italy, Marco Guglielmo, University Medical Center Utrecht, Utrecht - The Netherlands, and Anna Giulia Pavon, Cardiocentro Ticino Institute, Lugano - Switzerland. Link to editorial Link to paper