

What's Up Docs?
BBC Radio 4
In this BBC Radio 4 podcast, Drs Chris and Xand van Tulleken are on a mission to help us take better care of ourselves.Although they are identical twins, Chris and Xand are very different and they never stop thinking and arguing about science and health. They want to lead healthy, happy lives and as doctors, they want this for everyone. Yet they tussle over how best to get there.When it comes to looking after our own health, it can be confusing. Medicine and science produce amazing new treatments and diagnostics every day and we are bombarded with so many headlines and pieces of advice; but how are we supposed to know what's really best for us and then successfully apply it to our lives?Drs Chris and Xand van Tulleken embrace this challenge; even as they marvel at the scientific breakthroughs, they grapple with the competing claims about health, wellbeing and how to live.From understanding testosterone therapies to microplastics in our diets, and the concept of 'hangriness' to the power of saying no - this podcast deals with the health stresses we all face every day, while taking on board how the decisions by corporations and governments affect all our health.Each episode, Chris and Xand are joined by an expert guest to examine the latest research, psychological insights, and data, to help listeners navigate the overwhelming amount of information and advice out there. They talk about the trials and tribulations in their own lives in their characteristically witty way - each teasing the other as they search for solutions. Xand has trouble sleeping , Chris has noisy knees, one of them has got an embarrassing itch. They have different ways of looking at things and find it really helpful to get the other one's point of view. These doctors are trying their best and encouraging listeners to do the same.Email: whatsupdocs@bbc.co.uk
Whatsapp: 08000 665123A Loftus Media production for BBC Radio 4.
Whatsapp: 08000 665123A Loftus Media production for BBC Radio 4.
Episodes
Mentioned books

Oct 7, 2025 • 32min
Doctors’ Notes: Nature
Baroness Kathy Willis, a biodiversity expert from Oxford University, dives into the fascinating ways nature impacts human health. She shares compelling clinical studies demonstrating how views of nature can expedite recovery and reduce stress. Kathy discusses the calming effects of specific landscapes and scents, revealing that our innate responses to natural stimuli can enhance well-being. She emphasizes the need for urban green spaces and policies to ensure everyone can access nature, reminding us that a thriving ecosystem benefits us all.

Oct 7, 2025 • 29min
Is nature good for you?
Join Professor Kathy Willis, a biodiversity expert from Oxford University, as she reveals fascinating links between nature and our health. She discusses how natural environments lower stress and enhance our microbiome, and outlines the calming effects of plant scents. Kathy explains that even 20 minutes in green spaces can measurably reduce stress. The conversation also touches on inequalities in access to nature and the importance of bringing nature indoors. Prepare to rethink your time outdoors and its profound benefits!

Sep 30, 2025 • 31min
Doctors' Notes: Psychedelics
Dr. James Rucker, a psychiatrist and psychedelic researcher at King's College London, dives into the fascinating world of psychedelics. He explains how these substances interact with brain receptors to foster new perspectives. The discussion highlights the contrast between traditional ceremonial use and modern recreational practices, as well as the myths surrounding microdosing, which shows little benefit beyond placebo. Rucker also touches on the evolving public perception of psychedelic research as curiosity grows and stigma wanes.

Sep 30, 2025 • 28min
Can psychedelics improve your mental health?
Dr. James Rucker, a consultant psychiatrist at King's College London, is leading groundbreaking trials on psilocybin for treatment-resistant depression. He explains how psychedelics stimulate serotonin receptors, offering insights into their potential therapeutic effects. Rucker details the structure of psilocybin therapy, emphasizing the profound benefits patients report, such as improved mood and lasting remission. The discussion also touches on the fine balance of using psychedelics respectfully within cultural contexts and cautioning recreational use.

Sep 23, 2025 • 18min
Doctors' Notes: Fibre
Dr. Deirdre Tobias, an obesity and nutritional epidemiologist at Brigham and Women's Hospital and Harvard Medical School, shares her insights on fibre and the microbiome. She emphasizes the complexity of gut health, cautioning against the oversimplification of microbiome tests and isolated supplements. The discussion also highlights how fibre-rich diets reflect whole foods and tackles the socioeconomic challenges tied to accessing healthy options. Listeners will come away with practical tips on increasing fibre intake, including budget-friendly options.

8 snips
Sep 23, 2025 • 29min
Are you getting enough fibre?
Dr. Deirdre Tobias, an obesity and nutritional epidemiologist from Harvard Medical School, delves into the essential role of dietary fiber in our health. She clarifies the difference between soluble and insoluble fiber and explains how it impacts digestion, heart disease, and diabetes. The conversation highlights practical ways to boost fiber intake through natural foods and addresses the effectiveness of supplements. Listeners gain actionable tips to enhance their diets without drastic changes while uncovering socio-economic factors that influence dietary choices.

20 snips
Sep 16, 2025 • 20min
Doctors' Notes: Backs
Mindy Cairns, a Specialist Musculoskeletal Physiotherapist and Associate Professor, shares her expertise on managing back pain. She discusses how mental health can influence back pain and offers tips for women during pregnancy. The conversation delves into the quest for the ideal sleep surface, emphasizing that comfort varies for everyone. Moreover, they explore the intricacies of diagnosing low back pain and the role of psychosocial factors in pain perception, making a case for a holistic approach to treatment.

23 snips
Sep 16, 2025 • 29min
How can you strengthen your back?
Dr. Mindy Cairns, a Specialist Musculoskeletal Physiotherapist and Associate Professor, sheds light on the complexities of back pain—a condition affecting 80% of us. She discusses its causes, effective management strategies, and the importance of maintaining an active lifestyle to strengthen our backs. The conversation also touches on the psychological impacts of pain and offers practical tips for coping. Plus, a quirky twist introduces 'fridgescaping,' connecting organization with healthy living!

8 snips
Sep 9, 2025 • 19min
Doctors' Notes: Magnesium
Join Professor Stella Volpe, a sports nutrition expert from Virginia Tech, as she delves into the intriguing relationship between magnesium, diabetes, and athletic performance. Discover why athletes might need to pay special attention to magnesium and learn about the importance of a balanced diet over supplements. With insights on navigating health misinformation in the age of social media, Stella's engaging discussion emphasizes consulting professionals before making dietary changes. Tune in for a blend of humor and essential nutrition wisdom!

Sep 9, 2025 • 28min
Should you take magnesium supplements?
Discover the wonders of magnesium in the human body and why it's gaining traction in wellness discussions. Learn about the risks of magnesium deficiency and the importance of a nutrient-rich diet over supplements. Experts share insights on dietary sources like nuts and seeds, stressing the benefits of whole foods. Uncover common misconceptions about magnesium supplementation and the need for caution in accepting health claims. Plus, enjoy a quirky twist as discussions bridge generational gaps through gaming, adding a playful note to the science.