Have you ever wondered how the first vaccine was made? It involves snorting scabs in China, ulcerous udders, and some good old fashioned child endangerment.  This week Corry takes us through the history and eradication of smallpox! References and Further Reading https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1069029/ https://www.who.int/csr/disease/smallpox/vaccines/en/ https://www.cdc.gov/smallpox/vaccine-basics/index.html Kennedy, Peter (1715). An Essay on External Remedies Wherein it is Considered, Whether all the curable Distempers incident to Human Bodies, may not be cured by Outward Means. London: A. Bell. https://www.britannica.com/science/cowpox https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810486/?tool=pubmed Support us on Patreon: patreon.com/SciGuys Watch us on YouTube: youtube.com/SciGuys Follow the Sci Guys @notcorry / @jampkin / @lukecutforth

This week the Sci Guys discuss a Steve Jobs wannabe that tricked everyone into thinking she had a revolutionary blood testing device. Jamp and Luke also discover why their blood cells might be a little bit prejudiced. References and Further Reading https://www.businessinsider.com/the-history-of-silicon-valley-unicorn-theranos-and-ceo-elizabeth-holmes-2018-5?r=US&IR=T#by-the-end-of-2017-theranos-was-in-need-of-a-cash-infusion-and-made-a-deal-with-fortress-investment-group-for-100-million-in-secured-debt-financing-to-get-it-through-2018-the-deal-relied-on-theranos-hitting-certain-development-milestones-as-it-worked-to-get-its-zika-virus-approved-by-the-fda-33 https://www.businessinsider.com/theranos-founder-ceo-elizabeth-holmes-life-story-bio-2018-4?r=US&IR=T#holmes-family-moved-when-she-was-young-from-washington-dc-to-houston-2 https://www.healthline.com/health/blood-tests https://www.nhlbi.nih.gov/health-topics/blood-tests https://www.nhs.uk/conditions/blood-tests/ https://www.medicalnewstoday.com/articles/196001.php https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=160&ContentID=36 Support us on Patreon: patreon.com/SciGuys Watch us on YouTube: youtube.com/SciGuys Follow the Sci Guys @notcorry / @jampkin / @lukecutforth

This week, Corry recounts humanity’s history of deep sea exploration, and the creatures that lurk in the shadows beneath.  Support us on Patreon: patreon.com/SciGuys Watch us on YouTube: youtube.com/SciGuys References and Further Reading 1. https://www.thoughtco.com/deep-sea-exploration-4161315 2. https://www.heraldscotland.com/business_hq/17888496.voyage-bottoms-sea-texan-scots-tackling-ocean-39-s-depths/ 3. https://www.whoi.edu/oceanus/feature/marine-snow-and-fecal-pellets/?id=2387&archives=true 4. https://www.bbc.co.uk/news/science-environment-49636756 5. https://newatlas.com/five-deeps-dsv-limiting-factor-mariana-trench/59690/ 6. https://fivedeeps.com/faq/ 7. https://relay.nationalgeographic.com/proxy/distribution/public/amp/news/2018/05/plastic-bag-mariana-trench-pollution-science-spd 8. https://www.nytimes.com/2015/09/15/science/piloted-deep-sea-research-is-bottoming-out.htm Follow the Sci Guys @notcorry / @jampkin / @lukecutforth

This week Corry talks about the benefits of eating poo (no really), and the tiny creatures controlling your brain! Tune in and you’ll also find out how to cure your depression with a yoghurt! References https://www.ncbi.nlm.nih.gov/pubmed/25624713 https://www.ncbi.nlm.nih.gov/pubmed/26824647  https://www.biorxiv.org/content/10.1101/036103v1 https://www.ncbi.nlm.nih.gov/pubmed/29171095 https://www.ncbi.nlm.nih.gov/pubmed/19043404 https://www.ncbi.nlm.nih.gov/pubmed/27818083  Escherich T (1885). "Die Darmbakterien des Neugeborenen und Säuglinge". Fortschr. Med. 3: 515–522. https://www.ncbi.nlm.nih.gov/pubmed/29795328 https://www.ncbi.nlm.nih.gov/pubmed/26718401 Kenner, Richardson; et al. (2010). "Shotgun sequencing: Review of progress in sequence assembly developments". Methods in Biomolecular Research. 38 (4): 1022–1035. You can find the rest of the references here: https://docs.google.com/document/d/1CHjN1hR_KdSgWLLB80tCx0Q46xm8O8IUAOXFdJNOEew Support us on Patreon: patreon.com/SciGuys Watch us on YouTube: youtube.com/SciGuys Follow the Sci Guys @notcorry / @jampkin / @lukecutforth

This week Corry tells us about a time in the 70s when a group of boys took role playing a little too far... Tune in to hear the truly incredible story of The Stanford Prison Experiment! References and Further Reading 1. https://web.stanford.edu/dept/spec_coll/uarch/exhibits/spe/Narration.pdf 2. https://www.prisonexp.org/ 3. https://www.bbc.co.uk/news/world-us-canada-14564182 4. https://psyarxiv.com/b7crx 5. https://blogs.scientificamerican.com/observations/rethinking-the-infamous-stanford-prison-experiment/ Support us on Patreon: patreon.com/SciGuys Watch us on YouTube: youtube.com/SciGuys Follow the Sci Guys @notcorry / @jampkin / @lukecutforth

This week Corry talks about how flying frogs led to discovering graphene, a super-powered substance that you can make with just a pencil and some tape! We also have a special guest, Jake Edwards, so tune in and join us for a ribbeting episode! You can see more of Jake on their YouTube channel: https://youtube.com/jakeftmagic References and Further Reading 1. https://www.nobelprize.org/prizes/physics/2010/geim/biographical/ 2. https://slate.com/business/2014/05/nobel-prize-in-physics-andre-geim-went-from-levitating-frogs-to-sciences-highest-honor.html 3. https://www.ru.nl/hfml/research/levitation/diamagnetic-levitation/ 4. http://en.wikipedia.org/wiki/Tesla_(unit) 5. https://www.newscientist.com/article/dn3785-gecko-tape-will-stick-you-to-ceiling/ 6. https://www.nobelprize.org/prizes/physics/2010/press-release/ Support us on Patreon: patreon.com/SciGuys Watch us on YouTube: youtube.com/SciGuys Follow the Sci Guys @notcorry / @jampkin / @lukecutforth

This episode was recorded live at Summer in the City. This week we talk about the indestructible water bears that we accidentally crashed on the moon. We also answer some burning questions from the audience! References and Further Reading Kinchin, Ian M. (1994) The Biology of Tardigrades, Ashgate Publishing http://www.bbc.co.uk/earth/story/20150313-the-toughest-animals-on-earth Support us on Patreon: patreon.com/SciGuys Watch us on YouTube: youtube.com/SciGuys Follow the Sci Guys @notcorry / @jampkin / @lukecutforth

This week we’re talking about the ideal black body with Daniel J Layton, and surprisingly it isn’t Janet Jackson’s. Tune in to find out why you don’t want to go near a black hole! You can find Dan on YouTube here: https://youtube.com/danieljlayton References and Further Reading 1.https://www.nasa.gov/audience/forstudents/5-8/features/nasa-knows/what-is-a-black-hole-58.html 2. https://www.space.com/15421-black-holes-facts-formation-discovery-sdcmp.html https://www.businessinsider.com/black-hole-how-big-largest-universe-2019-5?r=US&IR=T 3. https://www.theguardian.com/science/2019/apr/14/the-new-black-hole-what-can-we-really-see 4. https://www.bbc.co.uk/news/science-environment-47873592 5. https://www.wired.com/story/scientists-reveal-the-first-picture-of-a-black-hole/ 6. http://www.bbc.co.uk/earth/story/20150525-a-black-hole-would-clone-you 7. http://www.hawking.org.uk/into-a-black-hole.html 8. https://www.google.co.uk/amp/s/amp.theguardian.com/science/2019/apr/12/powehi-black-hole-gets-a-name-meaning-the-adorned-fathomless-dark-creation You can find a picture of the black hole here: https://media.wired.com/photos/5cadec1fb75f9b23c6466d74/master/pass/blackhole.jpg Support us on Patreon: patreon.com/SciGuys Watch us on YouTube: youtube.com/SciGuys Follow the Sci Guys @notcorry / @jampkin / @lukecutforth

This episode is all about firsts! We talk about the Wright Brothers and their invention of the first aeroplane with our very first special guest, Evan Edinger! You can see more of Evan on his YouTube channel: https://youtube.com/evan References & Further Reading: https://www.youtube.com/watch?v=01Q83yxdDaI https://www.history.com/topics/inventions/wright-brothers https://airandspace.si.edu/exhibitions/wright-brothers/online/a https://www.britannica.com/biography/Wright-brothers https://science.howstuffworks.com/transport/flight/modern/airplanes1.h Support us on Patreon: patreon.com/SciGuys Watch us on YouTube: youtube.com/SciGuys Follow the Sci Guys @notcorry / @jampkin / @lukecutforth

This episode is all about the (mad) scientist, Nikola Tesla and his rivalry with Thomas Edison! We also cover Tesla’s problematic views, insane inventions, and his crush on a dove!  References and Further Reading 1. https://www.energy.gov/articles/war-currents-ac-vs-dc-power 2. https://science.howstuffworks.com/innovation/famous-inventors/famous-nikola-tesla-inventions.htm 3. https://www.history.com/.amp/topics/inventions/nikola-tesla 4. https://www.history.com/.amp/news/6-brilliant-tesla-inventions-never-built 5. https://amp.interestingengineering.com/7-inventions-of-nikola-tesla-that-were-never-built 6. https://www.britannica.com/biography/Nikola-Tesla 7. https://www.biography.com/.amp/inventor/nikola-tesla 8. https://www.bbc.co.uk/programmes/topics/Nikola_Tesla 9. https://www.bbc.co.uk/programmes/articles/55mfzKcTrkgGcZv4VMsf24q/five-nikola-tesla-predictions-that-came-true 10. https://www.bbc.co.uk/news/magazine-19503846 11. https://amp.businessinsider.com/the-secret-life-of-nikola-tesla-2015-10 Support us on Patreon: patreon.com/SciGuys Watch us on YouTube: youtube.com/SciGuys Follow the Sci Guys @notcorry / @jampkin / @lukecutforth