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Sci Guys

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Nov 2, 2020 • 1h 22min

81: Gene Editing with CRISPR

This week we chat about the genetic revolution and the ethics of editing human DNA... You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys If you would like to support the podcast, please donate to our Patreon: http://patreon.com/SciGuys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References and Further Reading  https://www.britannica.com/science/DNA https://www.britannica.com/science/gene https://www.britannica.com/science/gene-editing#ref1272858 https://www.livescience.com/amp/58790-crispr-explained.html https://www.newscientist.com/term/what-is-crispr/ https://www.britannica.com/science/gene-editing https://www.nature.com/articles/d41586-019-03018-0 https://www.scientificamerican.com/article/despite-controversy-human-studies-of-crispr-move-forward-in-the-u-s/#:~:text=Despite%20Controversy%2C%20Human%20Studies%20of%20CRISPR%20Move%20Forward%20in%20the%20U.S.,-The%20technology%20that&text=Researchers%20in%20the%20U.S.%20have,trials%20of%20CRISPR%20in%20humans. https://www.theguardian.com/science/2020/mar/04/doctors-use-gene-editing-tool-crispr-inside-body-for-first-time https://www.newscientist.com/article/2208777-exclusive-five-couples-lined-up-for-crispr-babies-to-avoid-deafness/ https://www.cff.org/Research/Research-Into-the-Disease/Restore-CFTR-Function/Gene-Editing-for-Cystic-Fibrosis/ https://www.cff.org/Research/Research-Into-the-Disease/Restore-CFTR-Function/Gene-Delivery-for-Cystic-Fibrosis-Therapy/ https://www.nature.com/articles/d41586-020-01906-4 https://www.sciencemag.org/features/2019/09/beyond-crispr-what-s-current-and-upcoming-genome-editing https://www.youtube.com/watch?v=4YKFw2KZA5o Follow the Sci Guys @notcorry / @jampkin / @lukecutforth
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Oct 26, 2020 • 1h 23min

80: The Science of ADHD (with Kim Nieuwenhuis)

This week Kim joins us as we give you the A to Z on ADHD... Find Kim on her YouTube channel: https://www.youtube.com/OhItsJustKim You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys If you would like to support the podcast, please donate to our Patreon: http://patreon.com/SciGuys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References and Further Reading  https://www.nhs.uk/conditions/attention-deficit-hyperactivity-disorder-adhd/treatment/ https://www.nhs.uk/conditions/attention-deficit-hyperactivity-disorder-adhd/causes/ https://www.cdc.gov/ncbddd/adhd/facts.html https://pubmed.ncbi.nlm.nih.gov/?term=Cause+of+adhd https://pubmed.ncbi.nlm.nih.gov/24259638/ https://pubmed.ncbi.nlm.nih.gov/27189265/ https://pubmed.ncbi.nlm.nih.gov/30301823/ https://pubmed.ncbi.nlm.nih.gov/28091799/ https://pubmed.ncbi.nlm.nih.gov/22963644/ Psychobiology - Chris Chandler Follow the Sci Guys @notcorry / @jampkin / @lukecutforth
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Oct 19, 2020 • 50min

79: The Laughing Death

There was a curious disease found in New Guinea, that caused a very odd pattern of deaths. The reason for the outbreak turned out to be very simple, but you won’t believe it... You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys If you would like to support the podcast, please donate to our Patreon: http://patreon.com/SciGuys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References and Further Reading  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466359/ https://www.ninds.nih.gov/disorders/all-disorders/kuru-information-page https://text.npr.org/s.php?sId=482952588 https://www.cdc.gov/prions/index.html https://www.nhs.uk/conditions/creutzfeldt-jakob-disease-cjd/ https://www.scientificamerican.com/article/what-is-a-prion-specifica/ https://www.cdc.gov/prions/bse/index.html https://www.fda.gov/animal-veterinary/animal-health-literacy/all-about-bse-mad-cow-disease https://link.springer.com/chapter/10.1007/0-387-21755-X_3 https://pubmed.ncbi.nlm.nih.gov/20948292/ https://pubmed.ncbi.nlm.nih.gov/25131595/ https://pubmed.ncbi.nlm.nih.gov/24189576/ https://pubmed.ncbi.nlm.nih.gov/28109329/ https://pubmed.ncbi.nlm.nih.gov/18558863/ https://people.howstuffworks.com/cannibalism8.htm https://www.businessinsider.com/why-self-cannibalism-is-bad-idea-2018-5?amp&r=US&IR=T https://www.nature.com/articles/srep44707/tables/2 https://www.wired.co.uk/article/lab-grown-human-meat-cannibalism https://api.nationalgeographic.com/distribution/public/amp/news/2017/02/cannibalism-common-natural-history-bill-schutt Follow the Sci Guys @notcorry / @jampkin / @lukecutforth
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Oct 12, 2020 • 1h 4min

78: Misophonia: Sound Rage

Can’t stand the sound of people eating? You’re not alone... You might even have a medical condition! You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys If you would like to support the podcast, please donate to our Patreon: http://patreon.com/SciGuys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References and Further Reading  https://www.nhs.uk/conditions/hyperacusis/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562945/#!po=0.793651 https://misophoniatreatment.com/wp-content/uploads/2014/06/A-MISO-S.pdf https://pubmed.ncbi.nlm.nih.gov/31066600/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034066/#!po=7.89474 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0054706 https://www.improbable.com/ig-about/winners/ https://www.improbable.com/ig-about/winners/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547634/#!po=1.21951 http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.1067.3711&rep=rep1&type=pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034066/#!po=7.89474 https://pubmed.ncbi.nlm.nih.gov/33005154/ https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0054706 Follow the Sci Guys @notcorry / @jampkin / @lukecutforth sciguys.co.uk
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Oct 5, 2020 • 1h 10min

77: Game Theory (with Evan Edinger)

This week Evan Edinger joins us to talk about game shows, A Beautiful Mind, and schizophrenia... Find Evan on his YouTube channel: http://youtube.com/evan You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys If you would like to support the podcast, please donate to our Patreon: http://patreon.com/SciGuys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References and Further Reading  https://www.google.co.uk/amp/s/www.livescience.com/amp/38936-mathematics.html https://www.google.co.uk/amp/s/amp.ft.com/content/f1ec9a54-a35f-11e2-ac00-00144feabdc0 http://euclid.trentu.ca/math/sb/misc/mathsci.html https://www.investopedia.com/terms/n/nash-equilibrium.asp https://www.britannica.com/science/game-theory https://www.nobelprize.org/prizes/economic-sciences/1994/nash/facts/ http://livingwithschizophreniauk.org/john-nash/ https://www.britannica.com/biography/John-Nash Follow the Sci Guys @notcorry / @jampkin / @lukecutforth sciguys.co.uk
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Sep 28, 2020 • 1h 26min

76: Mass Hysteria: The Dancing Plague

Our Patrons chose Mass Hysteria as the episode topic this week, so we’re talking about The Dancing Plague! In 1518 a French town was overcome with a contagious conclusion to dance til they dropped...  You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys If you would like to support the podcast, please donate to our Patreon: http://patreon.com/SciGuys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References and Further Reading  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536509/ https://www.mcgill.ca/oss/article/history-quackery/history-hysteria https://www.health.harvard.edu/newsletter_article/The_nocebo_response https://www.health.harvard.edu/mental-health/the-power-of-the-placebo-effect https://www.britannica.com/science/psychosomatic-disorder https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480686/ https://www.history.com/news/what-was-the-dancing-plague-of-1518 https://www.britannica.com/event/dancing-plague-of-1518 https://journals.lww.com/epidem/FullText/2010/09000/Frequency_and_Predictors_of_Mass_Psychogenic.31.aspx Follow the Sci Guys @notcorry / @jampkin / @lukecutforth sciguys.co.uk
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Sep 21, 2020 • 1h 6min

75: Eugenics & Birth Control (with Bliss)

This week, Bliss joins us talk about sexy no kid, otherwise known as “the pill”. How was it invented? Who was behind it? How was Eugenics involved? You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys If you would like to support the podcast, please donate to our Patreon: http://patreon.com/SciGuys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References and Further Reading  https://www.nhs.uk/conditions/contraception/combined-contraceptive-pill/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462239/ https://www.thecrimson.com/article/2017/9/28/the-bitter-pill/ T-to-test-the-birth-control-pill/ https://www.history.com/news/birth-control-pill-history-puerto-rico-enovid/ https://www.pbs.org/wgbh/americanexperience/features/pill-puerto-rico-pill-trials/ https://pdf.usaid.gov/pdf_docs/PNAAV359.pdf Follow the Sci Guys @notcorry / @jampkin / @lukecutforth sciguys.co.uk
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Sep 14, 2020 • 39min

74: The Psychedelic Disaster

Did the CIA spike a French Town? Or was it a case of contaminated bread? We might never know, but we do know that whatever happened resulted in a truly psychedelic disaster... You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys If you would like to support the podcast, please donate to our Patreon: http://patreon.com/SciGuys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References and Further Reading  https://www.britannica.com/science/ergot http://www.botany.hawaii.edu/faculty/wong/BOT135/LECT12.HTM https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640538/ https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/ergotism https://www.britannica.com/science/ergotism https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2069953/ https://www.bbc.co.uk/news/world-10996838 https://www.nytimes.com/2008/07/24/arts/24iht-blume.1.14718462.html https://www.mentalfloss.com/article/558020/pont-saint-esprit-france-1951-bread-poisoning-mass-hallucinations Follow the Sci Guys @notcorry / @jampkin / @lukecutforth sciguys.co.uk
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Sep 7, 2020 • 58min

73: Neuralink: Elon Musk's Brain Chip

This week Luke takes over to give us the lowdown on Elon Musk’s new venture that will hopefully link your mind to almost any kind of tech you could want! Are these brain chips dangerous? Can they meet the expectations Elon has set? Find out in this week’s episode on Neuralink! You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys If you would like to support the podcast, please donate to our Patreon: http://patreon.com/SciGuys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References and Further Reading  http://neurosky.com/2015/06/what-is-bci-and-how-did-it-evolve/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920041/ https://abcnews.go.com/Health/elon-musk-unveils-brain-chip-implant-fitbit-skull/story?id=72703840 https://www.jmir.org/2019/10/e16194/ https://www.nytimes.com/2019/07/16/technology/neuralink-elon-musk.html https://www.youtube.com/watch?v=Gqdo57uky4o https://www.youtube.com/watch?v=iOWFXqT5MZ4 https://www.businessinsider.com/we-spoke-to-2-neuroscientists-about-how-exciting-elon-musks-neuralink-really-is-2019-9?r=US&IR=T https://www.medicaldevice-network.com/features/neuralink-fact-fiction/ http://neurosky.com/2015/06/what-is-bci-and-how-did-it-evolve/ Follow the Sci Guys @notcorry / @jampkin / @lukecutforth sciguys.co.uk
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Aug 31, 2020 • 34min

72: The Stolen Cure for Leprosy

Ever heard of Alice Ball? No? There’s a pretty awful reason why you haven’t... This week’s episode has all the answers you need to one of the most scandalous stories you’ve never heard You can WATCH the podcast over on our YouTube channel: http://youtube.com/SciGuys If you would like to support the podcast, please donate to our Patreon: http://patreon.com/SciGuys If you'd like to see more of us, follow our socials! Facebook http://facebook.com/SciGuysPod Twitter http://twitter.com/SciGuysPod Instagram http://instagram.com/SciGuysPod References and Further Reading  https://scientificwomen.net/women/ball-alice-121 https://www.newscientist.com/article/mg24732910-900-alice-ball-pioneered-leprosy-treatment-and-then-had-her-work-stolen/ https://oumnh.ox.ac.uk/alice-ball https://www.biography.com/.amp/scientist/alice-ball https://www.who.int/news-room/fact-sheets/detail/leprosy https://www.lepra.org.uk/what-we-do/leprosy https://www.cdc.gov/leprosy/treatment/index.html Follow the Sci Guys @notcorry / @jampkin / @lukecutforth sciguys.co.uk

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