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Sci Guys

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Apr 29, 2024 • 1h 13min

263: The Cass Review REVIEW (with NOAHFINNCE)

Check out Noah’s music! Massive thanks to Evan for vision mixing and keeping us relatively sane: https://youtube.com/evan You can WATCH the podcast over on our YouTube channel Help keep the show running by supporting us on Patreon! If you'd like to see more of us, follow our socials! sciguys.co.uk TikTok Twitter Instagram Facebook If you spot any points that need correcting, head to sciguys.co.uk/corrections Follow the Sci Guys @notcorry / @lukecutforth References & Further Reading Background https://www.cancer.gov/publications/dictionaries/cancer-terms/def/double-blind-study https://www.rcpch.ac.uk/about-us/our-team/dr-hilary-cass https://www.theguardian.com/society/2024/apr/18/hilary-cass-report-and-the-trans-rights-debate https://www.theguardian.com/society/2024/apr/20/doctor-hilary-cass-warned-of-threats-to-safety-after-vile-abuse-over-nhs-gender-services-review https://www.youtube.com/watch?v=aeY1BkCxwoI Puberty Blockers https://tavistockandportman.nhs.uk/news/early-intervention-study-shows-puberty-blockers-are-a-well-received-intervention-in-carefully-selected-patients/ https://pubmed.ncbi.nlm.nih.gov/33529227/ https://www.plannedparenthood.org/learn/teens/puberty/what-are-puberty-blockers https://www.scientificamerican.com/article/what-are-puberty-blockers-and-how-do-they-work/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9793415/ https://www.nytimes.com/2021/05/11/well/family/what-are-puberty-blockers.html https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218488 https://www.ncbi.nlm.nih.gov/books/NBK547863/ https://ncbi.nlm.nih.gov/pmc/articles/PMC9577333/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344188/ https://www.ncbi.nlm.nih.gov/books/NBK551662/ https://www.nejm.org/doi/full/10.1056/NEJM198112243052602 https://wayback.archive-it.org/7993/20170112031859/http:/www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm209842.htm Cass Review https://cass.independent-review.uk/ https://cass.independent-review.uk/home/publications/final-report/ file:///Users/notcorry/Desktop/CassReview_Final.pdf https://www.england.nhs.uk/commissioning/spec-services/npc-crg/gender-dysphoria-clinical-programme/implementing-advice-from-the-cass-review/ Criticisms https://www.youtube.com/watch?v=qGZ1Gfu7XXw https://www.thepinknews.com/2022/11/03/tavistock-experts-criticise-acp-uk/ https://www.advocate.com/health/hilary-cass-nhs-report-debunked https://stonewall.org.uk/cass-review https://www.equalityhumanrights.com/statement-final-report-cass-review
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Apr 22, 2024 • 1h 35min

262: The Science of Weed (with @NOAHFINNCE ) | ANNIVERSARY SPECIAL

The 5th anniversary of Sci Guys means it’s high time we spoke about marijuana. Literally… It’s high time. Check out Noah’s music: https://tr.ee/f9DikNPhdQ Massive thanks to Evan for vision mixing and keeping us relatively sane: https://youtube.com/evan You can WATCH the podcast over on our YouTube channel Help keep the show running by supporting us on Patreon! If you'd like to see more of us, follow our socials! sciguys.co.uk TikTok Twitter Instagram Facebook If you spot any points that need correcting, head to sciguys.co.uk/corrections Follow the Sci Guys @notcorry / @lukecutforth References & Further Reading Cannabis Background & Basics Cannabis | WHO https://www.who.int/teams/mental-health-and-substance-use/alcohol-drugs-and-addictive-behaviours/drugs-psychoactive/cannabis Marijuana | History, Effects, THC, & Legality | Britannica https://www.britannica.com/science/marijuana Hashish | Cannabis, THC, Intoxication | Britannica https://www.britannica.com/science/hashish Cannabis (Marijuana) DrugFacts | National Institute on Drug Abuse (NIDA) https://nida.nih.gov/publications/drugfacts/cannabis-marijuana What We Know About Marijuana https://www.cdc.gov/marijuana/what-we-know.html The Name of Cannabis: A Short Guide for Nonbotanists - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531363/ Hemp | Description, Products, Seeds, Fiber, & Uses | Britannica https://www.britannica.com/plant/hemp Marijuana and the Brain - How Marijuana Works | HowStuffWorks https://science.howstuffworks.com/marijuana3.htm Legality of cannabis - Wikipedia https://en.wikipedia.org/wiki/Legality_of_cannabis History of Cannabis History of cannabis and the endocannabinoid system - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605027/ On the Preparations of the Indian Hemp, or Gunjah (Cannabis Indica), Their Effects on the Animal System in Health, and Their Utility in the Treatment of Tetanus and Other Convulsive Diseases https://pubmed.ncbi.nlm.nih.gov/30161735/ Oldest evidence of marijuana use discovered in 2500-year-old cemetery in peaks of western China | Science https://www.science.org/content/article/oldest-evidence-marijuana-use-discovered-2500-year-old-cemetery-peaks-western-china Effects of Cannabis Use Adverse Health Effects of Marijuana Use - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827335/ Use of Marijuana: Effect on Brain Health: A Scientific Statement From the American Heart Association https://pubmed.ncbi.nlm.nih.gov/35142225/ Edible marijuana products and potential risks for pediatric populations https://pubmed.ncbi.nlm.nih.gov/35634702/ The Scientific History of Cannabinoids | Science| Smithsonian Magazine https://www.smithsonianmag.com/science-nature/the-scientific-history-of-cannabinoids-180981561/ Health Effects | Marijuana | CDC https://www.cdc.gov/marijuana/health-effects/index.html How does marijuana affect the brain? Psychological researchers examine impact on different age groups over time https://www.apa.org/monitor/2023/06/marijuana-effects-brain Can cannabis kill? Characteristics of deaths following cannabis use in England (1998–2020) - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9716494 https://www.cancer.org/cancer/managing-cancer/treatment-types/complementary-and-integrative-medicine/marijuana-and-cancer.html https://www.dea.gov/drug-information/drug-scheduling
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Apr 15, 2024 • 50min

261: The Science of Magic Mushrooms (with NOAHFINNCE)

You can WATCH the podcast over on our YouTube channel Help keep the show running by supporting us on Patreon! If you'd like to see more of us, follow our socials! sciguys.co.uk TikTok Twitter Instagram Facebook If you spot any points that need correcting, head to sciguys.co.uk/corrections Follow the Sci Guys @notcorry / @lukecutforth References & Further Reading https://www.britannica.com/science/fungus https://www.britannica.com/science/fungus https://pubmed.ncbi.nlm.nih.gov/22887928/ https://www.britannica.com/science/sclerotium https://science.howstuffworks.com/magic-mushroom6.htm https://www.dea.gov/sites/default/files/2020-06/Psilocybin-2020_0.pdf https://science.howstuffworks.com/magic-mushroom6.htm https://www.canada.ca/en/health-canada/services/substance-use/controlled-illegal-drugs/magic-mushrooms.html https://asm.org/articles/2023/february/psilocybin-and-mental-health-the-magic-in-the-mush https://adf.org.au/drug-facts/psilocybin/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277578/ https://idp.nature.com/authorize?response_type=cookie&client_id=grover&redirect_uri=https%3A%2F%2Fwww.nature.com%2Farticles%2Fs41598-020-59282-y https://www.standard.co.uk/news/health/trial-magic-mushrooms-psilocybin-depression-maudsley-hospital-london-b1120423.html https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901083/ https://adf.org.au/insights/magic-mushrooms-medicine/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007659/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156539/ https://www.theguardian.com/society/2023/dec/14/magic-mushroom-use-grows-in-england-and-wales-ons-figures-show https://www.amsterdam.info/drugs/ https://en.wikipedia.org/wiki/Legal_status_of_psilocybin_mushrooms
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Apr 8, 2024 • 1h 13min

260: The Science of MDMA

This week we're talking about Molly, and Mandy, or whatever woman's name you want to call MDMA... You can WATCH the podcast over on our YouTube channel Help keep the show running by supporting us on Patreon! If you'd like to see more of us, follow our socials! sciguys.co.uk TikTok Twitter Instagram Facebook If you spot any points that need correcting, head to sciguys.co.uk/corrections Follow the Sci Guys @notcorry / @lukecutforth References & Further Reading https://www.history.com/topics/crime/history-of-mdma https://nida.nih.gov/publications/research-reports/mdma-ecstasy-abuse/what-are-mdmas-effects-on-brain https://nida.nih.gov/publications/research-reports/mdma-ecstasy-abuse/what-are-mdmas-effects-on-brain https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878040/ https://www.youtube.com/watch?v=jEAr7ThsYew https://www.ncbi.nlm.nih.gov/books/NBK538482/ https://www.hopkinsmedicine.org/news/newsroom/news-releases/2019/04/psychedelic-drug-mdma-may-reawaken-critical-period-in-brain-to-help-treat-ptsd https://pubmed.ncbi.nlm.nih.gov/34708874/ https://www.nature.com/articles/s41591-021-01336-3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820588/ https://pubmed.ncbi.nlm.nih.gov/24006318/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639540/ https://www.ncbi.nlm.nih.gov/books/NBK482377/
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Apr 1, 2024 • 1h 3min

259: The Science of Weight Loss Drugs: Wegovy & Ozempic

People are using a diabetes drug to lose weight, but does it actually owrk? Are there any risks? Should we even be using drugs for fat loss at all? You can WATCH the podcast over on our YouTube channel Help keep the show running by supporting us on Patreon! If you'd like to see more of us, follow our socials! sciguys.co.uk TikTok Twitter Instagram Facebook If you spot any points that need correcting, head to sciguys.co.uk/corrections Follow the Sci Guys @notcorry / @lukecutforth References & Further Reading https://www.ncbi.nlm.nih.gov/books/NBK562269/ https://healthmedia.blog.gov.uk/2023/09/04/accessing-wegovy-for-weight-loss-everything-you-need-to-know/ https://tspace.library.utoronto.ca/bitstream/1807/129409/2/AMED.2023.9946924.pdf https://www.ncbi.nlm.nih.gov/books/NBK551568/ https://health.ucdavis.edu/blog/cultivating-health/ozempic-for-weight-loss-does-it-work-and-what-do-experts-recommend/2023/07 https://www.diabetes.org.uk/about-us/news-and-views/ozempic-and-weight-loss-facts-behind-headlines https://www.nytimes.com/2022/11/22/well/ozempic-diabetes-weight-loss.html https://pubmed.ncbi.nlm.nih.gov/38300808/ https://pubmed.ncbi.nlm.nih.gov/38230266/ https://www.nice.org.uk/guidance/ta875/chapter/2-Information-about-semaglutide https://www.youtube.com/watch?v=laPaezEsteI https://www.who.int/health-topics/obesity#tab=tab_3 https://www.nhs.uk/conditions/obesity/ https://www.niddk.nih.gov/health-information/diabetes/overview/what-is-diabetes/type-2-diabetes https://www.nhs.uk/conditions/type-2-diabetes/symptoms/ https://www.pewresearch.org/science/2024/02/26/how-americans-view-weight-loss-drugs-and-their-potential-impact-on-obesity-in-the-u-s/ https://medlineplus.gov/druginfo/meds/a618008.html https://www.nhs.uk/conditions/type-1-diabetes/about-type-1-diabetes/what-is-type-1-diabetes/
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Mar 25, 2024 • 1h 4min

258: Alexithymia: The Science of Emotional Blindness (with @NOAHFINNCE

Use code SCIGUYS at the link below to get an exclusive 60% off an annual Incogni plan: https://incogni.com/SCIGUYS Alexithymia is the inability to understand or recognise emotions, so this week Noah joins us to talk about his feelings... You can WATCH the podcast over on our YouTube channel Help keep the show running by supporting us on Patreon! If you'd like to see more of us, follow our socials! sciguys.co.uk TikTok Twitter Instagram Facebook If you spot any points that need correcting, head to sciguys.co.uk/corrections Follow the Sci Guys @notcorry / @lukecutforth References & Further Reading https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456171/ https://www.bbc.co.uk/news/uk-england-suffolk-64253360 https://neuro.psychiatryonline.org/doi/10.1176/appi.neuropsych.14070169 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056680/ https://www.britannica.com/science/emotion/The-structure-of-emotions https://www.sciencefocus.com/the-human-body/what-are-emotions https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7005782/
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Mar 18, 2024 • 1h 2min

257: The Science of Pregnancy (with Rebecca Hanssen)

Use code SCIGUYS at the link below to get an exclusive 60% off an annual Incogni plan: https://incogni.com/SCIGUYS Luke is having a baby - surprise! So this week we're joined by the lovely Rebecca Hanssen to chat about pregnancy & the absolutely insane effects it has on the body... Grab yourself some merch! You can WATCH the podcast over on our YouTube channel Help keep the show running by supporting us on Patreon! If you'd like to see more of us, follow our socials! sciguys.co.uk TikTok Twitter Instagram Facebook If you spot any points that need correcting, head to sciguys.co.uk/corrections Follow the Sci Guys @notcorry / @lukecutforth References & Further Reading https://www.ncbi.nlm.nih.gov/books/NBK559304/#:~:text=Pregnancy%20is%20a%20state%20of,to%20sustain%20the%20growing%20fetus. https://www.britannica.com/science/pregnancy/Anatomic-and-physiologic-changes-in-other-organs-and-tissues https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928162/ https://www.npr.org/sections/health-shots/2023/04/12/1159753316/pregnancy-start-conception https://www.cam.ac.uk/stories/pregnancy-sickness-cause https://www.nhs.uk/pregnancy/related-conditions/common-symptoms/vomiting-and-morning-sickness/ https://www.cdc.gov/ncbddd/folicacid/about.html#:~:text=Why%20folic%20acid%20is%20important,and%20spine%20(spina%20bifida). https://www.nhs.uk/pregnancy/related-conditions/common-symptoms/bleeding-gums/
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Mar 11, 2024 • 58min

256: The Science of The Challenger Explosion

Delve into the critical safety oversights that led to the Challenger disaster, revealing ignored warnings and the pressures influencing NASA's launch decisions. The hosts humorously connect modern media's evolution and public interest in space travel. Uncover the tragic implications of design flaws, particularly the O-rings, and the psychological impacts on those involved. Reflect on the ethical dilemmas between corporate interests and safety, all while dissecting the legacy of the tragedy with a mix of humor and critical analysis.
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Mar 4, 2024 • 1h 37min

255: The Science of Free Money (Universal Basic Income)

Delving into the Science of Universal Basic Income, the podcast explores its impacts on work ethic and Capitalism. From UBI trials worldwide to the health benefits, the discussion covers its historical origins and potential societal implications. Alaska's unique dividend system and the motivation behind cash payments are also explored, along with the challenges and outcomes of UBI trials.
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Feb 26, 2024 • 57min

254: The Science of Dyslexia

Trouble reading this? You might need glasses, or... you could be dyslexic - which, thanks to our patrons, is exactly what we're talking about this week! Grab yourself some merch! You can WATCH the podcast over on our YouTube channel Help keep the show running by supporting us on Patreon! If you'd like to see more of us, follow our socials! sciguys.co.uk TikTok Twitter Instagram Facebook If you spot any points that need correcting, head to sciguys.co.uk/corrections Follow the Sci Guys @notcorry / @lukecutforth References and Further Reading https://www.nhs.uk/conditions/dyslexia/diagnosis/ https://www.nhs.uk/conditions/dyslexia/symptoms/ https://www.ncbi.nlm.nih.gov/books/NBK557668/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967798/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430506/ https://pubmed.ncbi.nlm.nih.gov/30458541/ https://www.researchgate.net/publication/320507873_Dyslexia_and_Specific_Learning_Disorders_New_International_Diagnostic_Criteria https://www.psychiatry.org/patients-families/specific-learning-disorder/what-is-specific-learning-disorder https://www.bdadyslexia.org.uk/dyslexia/how-is-dyslexia-diagnosed

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