Jack Scannell is a consultant, researcher, and entrepreneur. Jack is one of the world’s leading authorities on pharmaceutical R&D productivity. He co-authored the influential 2012 paper in Nature Reviews Drug Discovery that introduced “Eroom’s Law,” a concept highlighting how drug discovery has become slower and more expensive over time—essentially the opposite of Moore’s Law. Scannell has advised major pharmaceutical firms and is a noted commentator on strategies to improve innovation efficiency in the life sciences. He is currently building Ethereos.Explore Infinita City:* Explore the Archive: The Infinita City Times* Visit Infinita City* Join the Builders’ Hub on Telegram* Follow Infinita City on X This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com

Jean-Philippe (JP) Vergne is an Associate Professor of Strategy at Western University’s Ivey Business School, renowned for his research on organizations operating at the fringes of legality—particularly pirates. Along with Rodolphe Durand, he co-authored The Pirate Organization: Lessons from the Fringes of Capitalism, which explores how historical piracy and other unconventional ventures can shed light on modern forms of competition, regulation, and innovation. JP Vergne’s work extends to topics such as crypto governance, the historical development of organizations, and the evolution of capitalism.Book Reference: The Pirate Organization: Lessons from the Fringes of CapitalismExplore Infinita City:* Explore the Archive: The Infinita City Times* Visit Infinita City* Join the Builders’ Hub on Telegram* Follow Infinita City on X This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com

Ivan Morgunov is an experienced entrepreneur driven by the goal of stopping aging. He founded Longaevus Technologies, a venture studio in the field of longevity, and Unlimited Bio—one of the two companies that administer genetic therapies in Prospera Dr. Anna Vakhrusheva has over a decade of experience in advancing vaccines and gene therapies. She led the development of Russia’s first recombinant SARS-CoV-2 vaccine (Betuvax JSC), driving it from R&D to clinical trials within two years. As a co-founder of Unlimited Bio, she spearheads genetic therapy research, translating cutting-edge science into real-world longevity solutions.In this episode, Anna & Ivan describe their journey to start a biotech company in Prospera, their novel thesis on why business model innovation matters to solve aging, the opportunity of “cocktail therapies”, regulatory fast-track options and challenges in a new jurisdiction.Explore Infinita City:* Explore the Archive: The Infinita City Times* Visit Infinita City* Join the Builders’ Hub on Telegram* Follow Infinita City on X This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com

Nathan Cheng is a community builder, educator, and investor in the longevity biotech field. He has been closely involved with key initiatives such as the Longevity Biotech Fellowship (LBF), Healthspan Capital, and Longevity List, working to solve the problem of aging and death.In this conversation, Nathan Cheng discusses his journey into the longevity biotech field, exploring the quest for an indefinite lifespan and the various strategies to combat aging. He shares insights on community building, the importance of understanding aging, and the potential of biotechnology in extending life. The conversation also delves into the technical roadmap for solving aging, replacement strategies, and the role of cryonics as a last resort. In this conversation, Nathan Chang and Niklas Anzinger discuss the importance of mission-driven research in the field of longevity, emphasizing the need for focused efforts to tackle aging and death. They explore the role of the Longevity Biotech Fellowship in mobilizing talent and fostering collaboration among diverse professionals. The discussion also touches on effective communication strategies for the longevity mission, the catalysts for progress in the field, and the opportunities for newcomers to enter the longevity space. Finally, they introduce the Vitalism Foundation, which aims to unify efforts in the longevity movement under a shared ideology.Get involved & More about Nathan's work:* Longevity Biotech Fellowship (10% off for Infinitians)* Vitalist Bay (10% off for Infinitians)* Vitalism FoundationExplore Infinita City:* Explore the Archive: The Infinita City Times* Visit Infinita City* Join the Builders’ Hub on Telegram* Follow Infinita City on X This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com

Samo Burja, a researcher and founder of Bismarck Analysis, dives deep into the dynamics of institutions and their rapid development. He challenges the notion of slow evolution, emphasizing the role of 'great founders' in shaping history. Burja discusses the fragility of technological progress and cautions against censorship that jeopardizes knowledge. He advocates for special economic zones to spark innovation and argues for an adaptable leadership approach to navigate societal challenges. The conversation intertwines courage, institutional frameworks, and the future of humanity.

Terence Kealey, a British biochemist and former Vice-Chancellor of the University of Buckingham, discusses the pitfalls of government funding in science. He reveals his ambitious new initiative on Roatan, embodying a neo-medieval governance model focused on educational empowerment and innovation. The conversation also critiques the monopolization of thought within academia, advocating for a decentralized approach to scientific funding. Kealey's insights challenge long-held beliefs about scientific objectivity and the financial underpinnings of research, particularly in longevity.

Our guest is Anders Sandberg. Anders is a Swedish researcher, futurist and transhumanist. He holds a PhD in computational neuroscience from Stockholm University, and is a former senior research fellow at the Future of Humanity Institute at the University of Oxford.This conversation is about the governance of innovation, and the innovation of governance. Explore Infinita City:* Website: www.infinita.city* X: @InfinitaCity* The Infinita City Times* Join Events This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com

Brian is the Co-founder and CEO of Coinbase; he began his journey studying computer science and economics. Back early in his career, after a trip to Argentina and seeing hyperinflation, he was inspired by Bitcoin’s potential to update the financial system and increase economic freedom in the world.He started Coinbase in 2012, and by 2021, it had become a public company worth $50B by 2024.Post-IPO, he started thinking about longevity; he started organizing biotech dinners to explore innovative ideas. And this led him to found NewLimit, a company focused on epigenetic reprogramming to combat aging, utilizing machine learning to discover potential treatments.In this Fireside Chat, Brian discusses his vision for crypto and longevity with Niklas Anzinger, Vitalia's CEO, and Erick Brimen, Próspera's CEO. The conversation happened in the special economic zone of Próspera on the island of Roatán in Honduras. With a common law-based, pro-liberty legal system that is probably the most crypto-friendly in the world.In this special zone, Vitalia has started to build a community of longevity enthusiasts, crypto natives and biotech founders - taking advantage of expedited clinical trials and medical reciprocity laws that allow access to treatments approved in 30+ countries.Crypto Cities In The Real WorldBrian and the team of Coinbase Ventures visited Próspera and Vitalia to explore the possibilities for real-world crypto adoption, and how it can solve humanities’ biggest challenges. There are several existing uses and enormous opportunities for crypto to build real cities.That is why, we're excited to introduce –Crypto Cities Builders' Program (Oct 19 - Nov 19)We’re inviting crypto/web3 builders & founders to join us in Vitalia’s Roatán Hub, to build real solutions or accelerate your existing startups & projects.→ https://vitalia.city/cryptocitybuildersMore about Brian's work:* https://www.brianarmstrong.org/* https://www.coinbase.com/* https://www.newlimit.com/ This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com

Joe Lonsdale, a technology entrepreneur and managing partner at 8VC, discusses radical ideas for improving governance through new cities and network states. He highlights the failures of institutions like the SEC and FDA in fostering innovation. Lonsdale encourages entrepreneurs to address regulatory gaps in sectors like transportation and biotech. He shares inspiring global examples, like Vitalia City in Honduras, and advocates for a 'city-state' model to reinvigorate the U.S., likening it to Singapore’s impact on China.

Bradley Tusk is a cofounder of Tusk Venture Partners, which invests in early-stage technology companies operating in highly regulated industries.Bradley was also Uber's first political advisor and instrumental in developing their strategy to disrupt the incumbent taxi monopolies.This is one of the most fascinating stories in the recent history of regulatory hacking.In this episode, we're demystifying political misconceptions and looking into practical advice for entrepreneurs on navigating regulatory roadblocks and changing them for their benefit.Key Takeaways:* Every policy output is the result of political input. Every politician makes every decision solely based on reelection and nothing else.* The vast majority of companies are regulated in some way. Rather than avoid dealing with regulations, run with the mindset that you'll figure it out. * To hack the regulatory system, you need to take into consideration that:* 1) The level of government really matters—focus on doing things on a local or state level rather than a federal level;* 2) Get your customers to advocate for you More about Bradley's work:* bradleytusk.com* Tusk Venture Partners* Podcast – Firewall* Book – The Fixer: My Adventures Saving Startups from Death by Politics This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.infinitacitytimes.com