

Training Data
Sequoia Capital
Join us as we train our neural nets on the theme of the century: AI. Sonya Huang, Pat Grady and more Sequoia Capital partners host conversations with leading AI builders and researchers to ask critical questions and develop a deeper understanding of the evolving technologies—and their implications for technology, business and society.The content of this podcast does not constitute investment advice, an offer to provide investment advisory services, or an offer to sell or solicitation of an offer to buy an interest in any investment fund.
Episodes
Mentioned books

146 snips
Aug 5, 2025 • 1h 1min
Vercel CEO Guillermo Rauch: Building the Generative Web with AI
Guillermo Rauch, CEO of Vercel, is on a mission to demystify software creation, making it accessible to everyone. He discusses how AI tools like ChatGPT have transformed customer acquisition and reduced friction in coding. Guillermo emphasizes the shift toward ephemeral applications and the power of ‘virtual coworkers’ in design and development. He foresees a future where AI enhances user experiences and security in web applications, liberating software from traditional constraints and enabling real-time, personalized interactions.

165 snips
Jul 30, 2025 • 30min
OpenAI’s IMO Team on Why Models Are Finally Solving Elite-Level Math
Noam Brown and Alex Wei, members of OpenAI's IMO team, share their groundbreaking journey to achieve gold-level performance on International Mathematical Olympiad problems. They discuss their innovative approach using reinforcement learning techniques and admit the model's self-awareness in tackling tough challenges. The duo emphasizes the contrast between solving competition problems and genuine mathematical breakthroughs. They also explore the balance between formal and informal verification, highlighting the interplay of human oversight in developing advanced mathematical models.

280 snips
Jul 22, 2025 • 38min
OpenAI Just Released ChatGPT Agent, Its Most Powerful Agent Yet
Isa Fulford, Casey Chu, and Edward Sun from OpenAI's ChatGPT agent team share insights into their groundbreaking work on a powerful AI agent that integrates deep research with operator tasks. They reveal how this agent can perform complex, multi-step tasks by accessing a virtual computer and utilizing multiple tools simultaneously. The team discusses their reinforcement learning strategies, challenges faced during development, and the significance of safety measures. Their collaboration showcases how small teams can effectively innovate and enhance AI capabilities for real-world applications.

235 snips
Jul 11, 2025 • 41min
DeepMind's Pushmeet Kohli on AI's Scientific Revolution
Pushmeet Kohli leads AI for Science at DeepMind and spearheaded AlphaEvolve, an AI that discovers new algorithms and proves complex mathematical results. He discusses how AlphaEvolve is revolutionizing scientific methodologies, making strides in fields like chip design and materials science. Kohli describes the collaboration with mathematicians, the capabilities of Gemini models in refining hypotheses, and the broader transformative impacts of AI in healthcare and energy, shedding light on a future where AI drives unprecedented discoveries.

150 snips
Jul 8, 2025 • 47min
Mapping the Mind of a Neural Net: Goodfire’s Eric Ho on the Future of Interpretability
Eric Ho, founder of Goodfire, is at the forefront of AI interpretability, tackling the challenge of understanding neural networks. He shares breakthroughs in resolving superposition using sparse autoencoders and demonstrates innovative model editing techniques. The conversation touches on real-world applications, particularly in genomics, and the vital role of interpretability as AI grows in influence. Ho emphasizes the importance of independent research in making AI systems more transparent and mitigating risks associated with powerful technologies.

293 snips
Jul 1, 2025 • 60min
ElevenLabs’ Mati Staniszewski: Why Voice Will Be the Fundamental Interface for Tech
Mati Staniszewski, co-founder and CEO of ElevenLabs, dives into the world of audio innovation and its pivotal role in technology. He reveals how his company's breakthroughs in text-to-speech enhance emotional and contextual understanding. Mati discusses viral successes like crafting Darth Vader’s voice for Fortnite and enabling real-time translations, aimed at breaking language barriers. He also reflects on his journey from a high school friendship in Poland to leading a groundbreaking AI firm, emphasizing the transformative power of voice technology.

128 snips
Jun 24, 2025 • 41min
From DevOps ‘Heart Attacks’ to AI-Powered Diagnostics With Traversal’s AI Agents
Anish Agarwal and Raj Agrawal, co-founders of Traversal, are reshaping how enterprises tackle system failures with AI agents. They discuss the revolutionary speed of root cause analysis, slashing response times to mere minutes. The duo also explores the parallels between DevOps and healthcare, emphasizing a proactive approach to troubleshooting. With AI-generated code on the rise, they highlight the growing importance of AI in debugging and maintaining reliability. Their insights bridge academic research and real-world applications, showcasing the dynamic potential of AI in tech.

720 snips
Jun 17, 2025 • 49min
The Breakthroughs Needed for AGI Have Already Been Made: OpenAI Former Research Head Bob McGrew
Bob McGrew, former Head of Research at OpenAI, shares insights on AI's rapid evolution. He discusses the three essential pillars for artificial general intelligence: Transformers, scaled pre-training, and reasoning. McGrew predicts that 2025 will focus on reasoning as pre-training stagnates. He highlights how the agent economy will disrupt industries, including law and medicine, due to an abundance of AI services. Personal anecdotes reveal how his children use ChatGPT to fuel their curiosity, while he also explores opportunities for startups in AI and robotics.

307 snips
Jun 10, 2025 • 38min
OpenAI Codex Team: From Coding Autocomplete to Asynchronous Autonomous Agents
Hanson Wang, a researcher at OpenAI's Codex team, and Alexander Embiricos, product lead focused on agentic coding, delve into revolutionary coding agents that autonomously generate pull requests from simple prompts. They discuss training these AI models for real-world programming, the shift from AI as a pair to an independent agent, and envisioning a future where AI writes most code. Challenges around long-running inference and user task articulation are also explored, all while humorously comparing interactions with Codex to social media engagements.

258 snips
Jun 3, 2025 • 54min
Google I/O Afterparty: The Future of Human-AI Collaboration, From Veo to Mariner
Jaclyn Konzelmann, a Google Labs leader working on Project Mariner, discusses how this intelligent assistant enhances productivity by remembering context across tasks. Simon Tokumine highlights NotebookLM's evolution into a platform that personalizes information delivery. Thomas Iljic fascinates listeners with insights on merging filmmaking and gaming through generative AI in Whisk and Veo. The trio delves into creative media's future, the challenges of AI-powered e-commerce, and how user feedback shapes these innovative tools.