Health and Medicine (Audio)

A healthy microbiome can prevent disease and obesity. Dr. Sean Spencer discusses how a diet rich in fiber supports our health in various ways. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40458]

According to the World Health Organization (WHO) an estimated 1.3 billion people or 16% of the global population have a significant disability. A disability is a condition that can be mental or physical, and can affect a person's vision, movement, thinking, learning, communication, hearing, mental health or social relationships. However, not all disabilities are the same. Some disabilities are genetic, passed down from generation to generation, while others may have been caused by an incident out of the person's control. In this episode of Exploring Ethics, Professor Joseph Stramondo will discuss the narrative, identity and ethics of choosing disability. Series: "Exploring Ethics" [Health and Medicine] [Humanities] [Science] [Show ID: 40241]

Join us for a dynamic panel discussion where experts explore the contributions of Indigenous practices to modern agriculture. The conversation highlights traditional ecological knowledge, addresses gaps in food access, and proposes strategies to promote food sovereignty. Panelists examine how Indigenous wisdom and contemporary innovation create equitable, sustainable food systems, amplify Indigenous voices, and inspire collaboration for a resilient future. Series: "Future Thought Leaders" [Health and Medicine] [Agriculture] [Show ID: 40171]

Carissa Cascio, Ph.D., explores how autistic individuals perceive and process sensory experiences, focusing on internal sensations of the body, known as interoception, and their impact on emotions, anxiety, and sleep. Cascio highlights the challenges of heightened sensory awareness, including how it can disrupt rest, and underscores the importance of understanding these experiences to improve therapy and overall well-being. Cascio shares personal anecdotes and challenges myths about autism, emphasizing the rich internal worlds of autistic individuals. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Show ID: 40215]

Gordon Saxe, M.D., Ph.D., reveals the secrets to slowing down the aging process and living a healthier life. He uncovers how aging affects everything from our bones and muscles to our brain, leading to issues like memory loss, fatigue, and weakened immune responses. How can you make choices today that could help you live longer and feel better? Saxe dives into groundbreaking research on caloric restriction, a powerful tool for extending lifespan, and how a plant-based diet can prevent chronic diseases and improve overall health. He also shares practical tips on exercise, stress management, and social connection that can help you stay sharp, strong, and energized as you age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40322]

Martin Kampmann, Ph.D., explores how CRISPR screening and induced pluripotent stem cell (iPSC) technology can uncover new insights into neurological diseases such as Alzheimer's. His lab uses CRISPR to identify genes that influence protein aggregation and cellular vulnerability, focusing on neurons, astrocytes, and microglia derived from human stem cells. Kampmann highlights the roles of mitochondria, autophagy, and other cellular pathways in disease progression, emphasizing the importance of understanding both protective and damaging processes. He also discusses the potential contributions of glial cells—especially microglia and astrocytes—to neurodegeneration, sparking ideas for therapeutic targets. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39461]

Anthony Lim, M.D., J.D., explores how small, intentional steps can lead to lasting behavioral change. Lim breaks down a simple, four-step framework—awareness, intention, action, and reflection—to help people achieve their goals, whether it's improving health, forming better habits, or making positive life changes. Through real-life examples and insights from neuroscience, he emphasizes the power of connecting with your deeper "why," taking action, and practicing self-compassion. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40323]

Christine Wu Nordahl, Ph.F., offers an insightful exploration into the unique needs and experiences of autistic teens, focusing on fostering inclusive spaces. Highlighting themes of gender diversity, underdiagnosis in girls, and the impact of societal perceptions, she emphasizes the importance of tailored support for neurodiverse individuals. Through powerful participant stories and an inspiring poem, Nordahl underscores the resilience and creativity within the autistic community. Her passionate advocacy for better diagnostic tools and inclusive interventions makes this talk a must-watch for anyone seeking to understand and empower autistic youth. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Show ID: 40213]

Frank Furnari, Ph.D., and Alexander Khalessi, M.D., M.B.A., discuss exciting advancements in brain cancer research, focusing on glioblastoma, an aggressive and challenging tumor. They highlight how specific genetic mutations drive tumor growth and how targeting these mutations could lead to new treatments. They also delve into cutting-edge therapies, including using light to activate drugs aimed at combating cancer. A central theme of the talk is the complexity and ever-changing nature of these tumors, which makes them difficult to treat. However, technological breakthroughs, like single-cell genetic sequencing and lab-grown tumor models, are providing scientists with valuable insights into tumor behavior, paving the way for more personalized and effective treatment options in the future. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39871]

Le Xu, Ph.D., examines the intricate processes underlying lung development and disease, with a focus on idiopathic pulmonary fibrosis (IPF). Xu explores the roles of genetic and cellular mechanisms, including the hedgehog pathway, FGF signaling, and epithelial-mesenchymal interactions, in driving lung fibrosis. Xu also highlights links between congenital diaphragmatic hernia (CDH) and lung development, suggesting that both mechanical and genetic factors contribute to lung hypoplasia. The discussion includes the development of advanced mouse models that replicate key aspects of human IPF, offering insights into fibrosis progression. Xu's research ultimately seeks to identify the causes of lung tissue abnormalities and pave the way for targeted therapies. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39460]