Defiant Health Radio with Dr. William Davis

William Davis, MD
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Oct 22, 2025 • 8min

Why Weight Loss Can Be Harmful to Your Health

Yes, you can lose weight by reducing calories whether through a calorie-cutting diet, bariatric procedure, or pharmaceutical. But the effect is almost always temporary and followed by a return of weight followed by significant downturn in health. You were also likely not advised that losing weight by cutting calories, we now know through tracking of large numbers of people over many years, likely abbreviates your life by several years. In this and future podcasts, I will be introducing concepts that block these effects, concepts that I shall be exploring in even greater depth in my new book, Super Body. **Disclaimer:**The information presented in my books, blog posts, YouTube videos, podcasts, and other content is for informational and educational purposes only. The content I share should not be interpreted as medical advice, diagnosis, or treatment. Always consult with your personal physician or qualified healthcare professional before making any changes to your diet, medication, lifestyle, or healthcare regimen. Your individual health needs should be evaluated by a professional who is familiar with your unique medical history. I am also a co-founder and shareholder in Realize Therapeutics Corp.My new book is Super Body: A 3-Week Program to Harness the New Science of Body Composition and Restore Your Youthful ContoursAvailable on Amazon and other bookstores, now available for pre-order: Hachette (book publisher): https://www.hachettebookgroup.com/titles/william-davis-md/super-body/9780306835995/Amazon: https://www.amazon.com/gp/product/0306835991?tag=hacboogrosit-20Barnes & Noble: https://www.barnesandnoble.com/w/super-body-william-davis-md/1147241313?ean=9780306835995&st=AFF&2sid=Hachette%20Book%20Group_8040641_NA&sourceId=AFFHachette%20Book%20GroupBooks-a-Million: .https://www.booksamillion.com/p/9780306835995?cjdata=MXxOfDB8WXww&AID=11552245&PID=8040641&cjevent=dd19ff256e1711f081fe032d0a82b82dBookshop: https://bookshop.org/p/books/super-body-a-3-week-program-to-harness-the-new-science-of-body-composition-and-restore-your-youthful-contours/077984f489f568b2?ean=9780306835995&next=t&affiliate=2344Support the showYouTube channel: https://www.youtube.com/@WilliamDavisMD Blog: WilliamDavisMD.com Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com Books: Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight Wheat Belly: Lose the Wheat, Lose the Weight and Find Your Path Back to Health; revised & expanded ed
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4 snips
Oct 15, 2025 • 14min

Oxalate Hysteria

There are a number of people advocating a diet low in oxalates, essentially eliminating many green leafy vegetables, Brussels sprouts, asparagus, celery, most nuts, berries, cocoa, and numerous otherwise healthy foods. Unfortunately, this advice is misguided and based on an incomplete understanding of the evidence. While there is no harm in reducing dietary oxalates beyond inconvenience, lack of variety, and the absence of many genuinely healthy foods, reducing oxalate exposure is not the primary problem, just a Band-Aid. Oxalate hyperabsorption is due to disruption of the gastrointestinal microbiome: loss of the many species that metabolize oxalates but were eliminated or reduced due to antibiotic exposure, and the development of small intestinal bacterial overgrowth, SIBO, that is associated with abnormally increased oxalate absorption. Address the disrupted gastrointestinal and dietary oxalate consumption is no longer an issue for the vast majority of people.In this episode of the Defiant Health podcast, let’s discuss why so many people have been misled by this dietary oxalate issue and a smarter way to deal with what might be interpreted as oxalate intolerance. Support the showYouTube channel: https://www.youtube.com/@WilliamDavisMD Blog: WilliamDavisMD.com Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com Books: Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight Wheat Belly: Lose the Wheat, Lose the Weight and Find Your Path Back to Health; revised & expanded ed
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Sep 24, 2025 • 29min

What happens when you deprive yourself of blue light?

Science journalist Lynne Peeples did something extraordinary: She spent 10 days in a nuclear bunker exposed only to dim red light but no blue or other visible wavelength of light. She also rid the space of all clocks or other time-indicating devices and even avoided having any human contact. What she learned opened up numerous questions on how to best manage our day-to-day light exposure, wavelengths, and the implications they have on the quality of sleep, our moods, even various aspects of health and performance. After these sorts of unique experiences, along with discussions on circadian rhythms with numerous scientists working on this topic, Lynne comes to some unique conclusions. Lynne is the author of the book “The Inner Clock: Living in Sync with Our Circadian Rhythms” in which she explores the role of purposeful management of your circadian rhythm, your inner clock, for management of energy, focus, and mood. Here, Lynne and I talk about her novel insights, along with practical advice on how to better manage your light exposure and circadian rhythm. Lynne's book, The Inner Clock on Amazon:https://www.amazon.com/Inner-Clock-Living-Circadian-Rhythms/dp/0593538900/ref=tmm_hrd_swatch_0Lynne's YouTube channel: https://www.youtube.com/hashtag/lynnepeeples?app=desktopSupport the showYouTube channel: https://www.youtube.com/@WilliamDavisMD Blog: WilliamDavisMD.com Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com Books: Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight Wheat Belly: Lose the Wheat, Lose the Weight and Find Your Path Back to Health; revised & expanded ed
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Sep 17, 2025 • 13min

Why are you no longer hungry?

Discover how simple dietary strategies can revolutionize your appetite control. Learn about the role of gliadin-derived opioid peptides from grains in triggering unnatural cravings. Find out how managing insulin levels can foster a healthier relationship with food. Hear a powerful patient story highlighting the transformative effects of nutrition on chronic health conditions like coronary disease and rheumatoid arthritis. Embrace the balance between discipline and indulgence for optimal health!
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17 snips
Sep 9, 2025 • 18min

There's a 50:50 chance that you have this epidemic condition

A staggering 50% of people may be dealing with Small Intestinal Bacterial Overgrowth (SIBO), a condition linked to a host of health issues like depression, heart problems, and irritable bowel syndrome. The podcast delves into how SIBO disrupts gut health and spills harmful bacteria into the bloodstream. It offers practical remedies, including a unique fermented yogurt method to restore gut balance and prevent recurrence. Listeners learn to recognize the signs and take control of their health amidst this often-overlooked epidemic.
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Sep 3, 2025 • 10min

Here's a microbe you should know about: Bacillus subtilis

Discover the incredible benefits of Bacillus subtilis in gut health! The discussion dives into how this microbe excels at combating small intestinal bacterial overgrowth (SIBO) by producing powerful bacteriocins. Learn about its historical significance and why it outshines Bacillus coagulans in promoting gastrointestinal wellness. This episode highlights how harnessing the power of Bacillus subtilis can help reclaim control over your digestive health.
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10 snips
Aug 29, 2025 • 19min

Yogurt That's Not Yogurt: My Accidental Sleep Cure

Explore the intriguing link between gut health and sleep quality. Discover how the gut microbiome plays a pivotal role in determining your ability to rest, particularly focusing on the impact of endotoxemia. Hear personal stories of insomnia struggles and the surprising benefits of fermented foods. An innovative alternative resembling yogurt is introduced as a potential game-changer for enhancing sleep patterns. This accessible approach could be the key to transforming your nights into restful experiences.
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Aug 28, 2025 • 18min

Misplaced blame

You’re walking down the street, minding your own business, just out to run some errands. You’re wearing a black jacket, running shoes, a baseball cap. You pass the doors of a bank. Suddenly, the bank’s doors fly open and a man runs out, a man wearing a black jacket and a baseball cap. You see him running at top speed, disappearing around a corner. Moments later, two policemen burst through the bank’s doors, spot you, roughly spin you around, handcuff and arrest you. It’s a clear case of mistaken identify, of blaming you for something you had nothing to do with. It’s wrong, it’s frightening, and can lead to all sorts of misery and trouble. You’re going to spend some time in jail, have to hire a lawyer, spend thousands of dollars to defend yourself against accusations that were unimaginable just a short time before. Sounds awful, doesn’t it? Well, similar scenarios play out in health information every day: Something—a component of diet, a blood marker, a lifestyle practice—is wrongly blamed for some health problem such as heart disease or skin rashes or depression.In this episode of the Defiant Health podcast, let’s discuss how, just as someone could be blamed for a crime they did not commit, all too often, some aspect of life or health is wrong incriminated for some unhealthy outcome. But learn to recognize this pattern and you will be better equipped to protect yourself and get closer to the truth. Support the showYouTube channel: https://www.youtube.com/@WilliamDavisMD Blog: WilliamDavisMD.com Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com Books: Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight Wheat Belly: Lose the Wheat, Lose the Weight and Find Your Path Back to Health; revised & expanded ed
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Aug 17, 2025 • 15min

Microbiome Madness

It’s truly an exciting time. The information and science surrounding the microbiome is exploding. It seems that a day doesn’t pass without some new, interesting insight emerges on microbiome questions,  providing us with unprecedented insights and strategies to get better control over health, weight management, aging, etc. Look at what we are accomplishing, for example, with our cultivation of L. reuteri and L. crispatus. But it also means that misinformation, misinterpretation, and sometimes misrepresentation are becoming more common, leading you to make mistakes that could yield ineffective or even harmful results. In this episode of the Defiant Health podcast, let's cut through the misinformation and get a better understanding of what is going on.  Support the showYouTube channel: https://www.youtube.com/@WilliamDavisMD Blog: WilliamDavisMD.com Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com Books: Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight Wheat Belly: Lose the Wheat, Lose the Weight and Find Your Path Back to Health; revised & expanded ed
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Aug 5, 2025 • 15min

What was this Wheat Belly thing all about?

When the first Wheat Belly book was released in 2011, it quickly leapt to centerstage, gaining a huge worldwide following. Millions of copies of the book were sold in 37 countries, the conversation was featured in major media from network news to Dr. Oz to . I don’t believe that this was due to my personal charm or charisma, but because it worked: people experienced unexpected and substantial health and weight loss benefits even if such things had eluded them for years. Well, over those 15 years, memories have faded and, sadly, some people have gradually gravitated back to consuming this thing that was essentially created in a laboratory with geneticists and farmers amplifying its toxic effects. People succumb to media, marketing, and the pressures of people around them who are ready to say things like “How can that possibly be true?” or “Everything in moderation” or “Just a little won’t hurt.”  In this episode of the Defiant Health podcast, let’s review the arguments I made in the original Wheat Belly book to remind you that, yes, this is among the most toxic things that has ever emerged from the food and agribusiness industries. Support the showYouTube channel: https://www.youtube.com/@WilliamDavisMD Blog: WilliamDavisMD.com Membership website for two-way Zoom group meetings: InnerCircle.DrDavisInfiniteHealth.com Books: Super Gut: The 4-Week Plan to Reprogram Your Microbiome, Restore Health, and Lose Weight Wheat Belly: Lose the Wheat, Lose the Weight and Find Your Path Back to Health; revised & expanded ed

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