BMJ Best Practice Podcast

Chronic congestive heart failure is a complex clinical syndrome that can result from any structural or functional cardiac disorder that impairs the ability of the ventricle to fill with or eject blood. It is a major and growing public health problem. In this podcast, Syed Wamique Yusuf, FACC, FRCPI Syed Wamique Yusuf, Professor of Medicine, Department of Cardiology, University of Texas MD Anderson Cancer Center, gives a clinical overview of the condition. For more on chronic congestive heart failure, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/61 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to Covid-19. Abigail Davis, GP and section editor, covers the latest evidence around vaccine immunogenicity in different immunosuppressed populations, as well as the use of interleukin-6 inhibitors in COVID-19 patients. And Emma Scott, section editor, updates us on mucormycosis, or black fungus infection in COVID-19 patients. For more, see: BMJ Best Practice's topic on COVID-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): new-learning.bmj.com/course/10065100 BMJ Learning COVID-19 in primary care module: new-learning.bmj.com/course/10065230 Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00676-0/fulltext Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19: https://www.nejm.org/doi/full/10.1056/NEJMoa2100433 WHO Therapeutics and COVID-19: living guideline: https://app.magicapp.org/#/guideline/nBkO1E/section/LrV7OL Indian Council of Medical Research advice on mucormycosis: https://www.icmr.gov.in/pdf/covid/techdoc/Mucormycosis_ADVISORY_FROM_ICMR_In_COVID19_time.pdf

Persistent depressive disorder is a category that includes various forms of chronic depression in which depressive symptoms are present 'more days than not' over at least a 2-year period (1 year in children and adolescents). David J. Hellerstein, Professor of Clinical Psychiatry, Columbia University Medical Center, gives us a clinical overview of the condition. For more on persistent depressive disorder, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/805 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Chronic sinusitis is inflammation of the paranasal sinuses lasting more than 12 weeks. Symptoms include facial pressure, rhinorrhoea, postnasal drainage, congestion, and general malaise. Raj Sindwani, Section Head of Rhinology, Sinus, and Skull Base Surgery, Head and Neck Institute, Cleveland Clinic Foundation, gives us a clinical overview of the condition. For more on chronic sinusitis, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/15 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Bulimia nervosa is an eating disorder, characterised by severe preoccupation about weight and body shape. Includes recurrent episodes of binge eating with compensatory mechanisms, such as self-induced vomiting, to prevent weight gain. Debra Safer, Associate Professor, Co-Director of Stanford Eating and Weight Disorders Program, Stanford University School of Medicine, gives us an overview of the condition. For more on bulimia nervosa, see BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/441 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Giant cell arteritis is a common form of vasculitis in people aged 50 years or older. The extracranial branches of the carotid artery are usually affected. Kenneth J. Warrington, Professor of Medicine, Mayo Clinic College of Medicine, gives us an overview of the condition. For more on giant cell arteritis, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/177 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Emma Scott, section editor, updates us on vaccination for pregnant and breastfeeding women. And Abigail Davis, GP and section editor, covers myocardial infarction and pre-existing respiratory conditions. For more, see: BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): new-learning.bmj.com/course/10065100 BMJ Learning covid-19 in primary care module: new-learning.bmj.com/course/10065230

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Emma Scott, section editor, updates us on vaccination and the risk of blood clots. And Abigail Davis, GP and section editor, covers acute kidney injury, venous thromboembolism prevention, and secondary bacterial pneumonia. For more, see: BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): new-learning.bmj.com/course/10065100 BMJ Learning covid-19 in primary care module: new-learning.bmj.com/course/10065230 EMA: ema.europa.eu/en/news/astrazenecas-covid-19-vaccine-ema-finds-possible-link-very-rare-cases-unusual-blood-clots-low-blood MHRA: gov.uk/government/news/mhra-issues-new-advice-concluding-a-possible-link-between-covid-19-vaccine-astrazeneca-and-extremely-rare-unlikely-to-occur-blood-clots JCVI: gov.uk/government/publications/use-of-the-astrazeneca-covid-19-vaccine-jcvi-statement/jcvi-statement-on-use-of-the-astrazeneca-covid-19-vaccine-7-april-2021 WHO: who.int/news/item/07-04-2021-interim-statement-of-the-covid-19-subcommittee-of-the-who-global-advisory-committee-on-vaccine-safety COVID-19 rapid guideline: managing COVID-19: nice.org.uk/guidance/NG191 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Depression can describe both a mood and an illness. Major depressive disorder is a clinical syndrome involving mood, neurovegetative functions, cognition, and behaviour. It affects 5% to 10% of patients in the primary care setting. Dean F. MacKinnon, Associate Professor, Psychiatry and Behavioral Sciences, The Johns Hopkins Hospital, Baltimore, gives us an overview of how to diagnose and manage depression in adults. For more on depression in adults, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/55 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Childhood constipation is typically characterised by infrequent bowel evacuations, large stools, and difficult or painful defecation. Symptoms may result from low fibre, poor nutrient, and/or insufficient water intake, which leads to excessive hardening of the stool. This often starts as an acute problem but can progress to faecal impaction and chronic constipation. Claire Zar-Kessler, Instructor in Pediatric Gastroenterology, Massachusetts General Hospital for Children, Boston gives us a clinical overview of the condition. Please always check the licensed indications for medications in your own country. For more on constipation in children, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/784 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.