What is synthetic biology and why is the “next Industrial Revolution”? Michael Specter joins Adam to discuss MRNA vaccines, stunning new developments in biotech, and why biology is more dangerous than nuclear weapons. Learn more about your ad choices. Visit megaphone.fm/adchoices See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Adam talks with legendary organizer Jane McAlevey about why organizing is the only way for unions, workers, and activists to win gains, and how to do it in practice. Pick up Jane’s book at http://factuallypod.com/books Learn more about your ad choices. Visit megaphone.fm/adchoices See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What the hell is laughter? Why do we do it, and what is its purpose? This week, psychoanalyst Nuar Alsadir joins Adam to discuss her theories about the origins of laughter, its effect on other people, and its purpose in various scenarios. Buy Nuar’s book at http://factuallypod.com/books Learn more about your ad choices. Visit megaphone.fm/adchoices See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Cory Doctorow and Adam Conover discuss how chokepoint capitalism impacts creative workers, monopolistic practices by big companies like YouTube and Amazon, challenges faced by content creators, and the need for intervention to prevent monopolies in various industries.

It’s a very scary time to be a trans person in America. An unprecedented onslaught of transphobic legislation is being pushed in state houses across the country, including more than two dozen bills that would to restrict access to healthcare for trans people. This week, Adam is joined by the executive director of the Transgender Law Center, Shelby Chestnut, to discuss the state of trans rights in America, and the legal challenges that trans people and their loved ones face. Learn more about your ad choices. Visit megaphone.fm/adchoices See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Adam invites one of his favorite guests Carlo Rovelli back to the show to talk about the deep history of science, the first physicist, and the conceptual revolutions in understanding that may still await us in the future. Learn more about your ad choices. Visit megaphone.fm/adchoices See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This week Adam is joined by theoretical cosmologist and particle physicist Chanda Prescod-Weinstein to discuss what the hell dark matter actually IS and how much we know about it, why being a particle physicist is not just about making things up, and how much better not just science, but human life would be if everyone had equal access to the beautiful project of understanding the natural world.  Learn more about your ad choices. Visit megaphone.fm/adchoices See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

All of us have too much to do and too little time to do it in. Yet the more we try to increase our productivity, the less happy and productive we seem to be. Why, and what’s the solution? This week Oliver Burkeman, author of Four Thousand Weeks, Time Management for Mortals, joins Adam to discuss how to break the cycle of productivity shame with his radical new approach to looking at time. Learn more about your ad choices. Visit megaphone.fm/adchoices See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Our dependency on cars isn’t just bad for traffic and the environment; it also forces many Americans to take on debt, or interact with our dangerous and deadly criminal justice system. Today on the show, Andrew Ross and Julie Livingston join Adam to talk about why cars, famously a symbol of freedom, actually consign many to imprisonment and death. Learn more about your ad choices. Visit megaphone.fm/adchoices See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

We know we’re going to die. So why don’t we act like it? This week, Adam is joined by Caitlin Doughty to discuss human composting, aquamation, green burial, how to reform the funeral industry, and how to finally accept the inevitable. Learn more about your ad choices. Visit megaphone.fm/adchoices See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.