
PSYCHOACTIVE
Drugs, drugs, drugs. Almost everyone uses them. Almost everyone has an opinion about them. Drug policy pioneer Ethan Nadelmann gets to the bottom of our strange relationship to drugs by talking with those who love them, hate them, and study them.
We’d love to hear your stories and ideas. Send us a note at psychoactive@protozoa.com or leave a voicemail at 1-833-PSYCHO-0 (1-833-779-2460).
Latest episodes

Dec 30, 2021 • 56min
Simeon Schnapper on Psychedelics and Venture Capital
Recent years have seen a dramatic increase in start-ups and investors developing psychedelic medicines. Simeon Schanpper is a founder and managing partner of JLS Fund, a venture capital fund investing in plant based and psychedelic medicines that aim to heal illness and enhance wellness. We talked about the tensions between philanthropic and for-profit investment, the challenges and opportunities of this explosive new sector, and his own fascinating personal journey which included running a medical marijuana dispensary and psychedelic art gallery in Venice Beach, California. Learn more about your ad-choices at https://www.iheartpodcastnetwork.comSee omnystudio.com/listener for privacy information.

Dec 23, 2021 • 51min
Stephen Jackson on Drugs, Sports, and George Floyd
For decades, sports have been regulating drug use among athletes, but of course, anytime you make a rule, people break it, and today we are going to talk to one of the NBA's best-known rule breakers. Stephen Jackson played fourteen years in the NBA, and he was described by Larry Bird as one of the toughest competitors he ever knew. Yet, throughout his whole career, he was a regular marijuana user. I'll talk to him today about why he found marijuana beneficial, how he managed to evade the system, and his unlikely and close relationship with George Floyd. Listen to this episode and let me know what you think. Our number is 1-833-779-2460. Our email is psychoactive@protozoa.com. Or tweet at me, @ethannadelmann. Learn more about your ad-choices at https://www.iheartpodcastnetwork.comSee omnystudio.com/listener for privacy information.

Dec 16, 2021 • 1h
Matt Culley on the Culture, Business & Politics of E-Cigarettes
Matt Culley was an early adopter of vaping and became a prominent vaping activist. He's also worked as a product designer, consultant, and is a board member of Consumer Advocates for Smoke-free Alternatives Association. In this episode, he explains how and why e-cigarettes emerged, how the products and industry have evolved, and why he thinks vape shops should be thought of as for-profit harm reduction centers.Listen to this episode and let me know what you think. Our number is 1-833-779-2460. Our email is psychoactive@protozoa.com. Or tweet at me, @ethannadelmann. Learn more about your ad-choices at https://www.iheartpodcastnetwork.comSee omnystudio.com/listener for privacy information.

Dec 9, 2021 • 43min
Dimitri Mugianis on Iboga, Addiction, and Healing
The first sentence to Dimitri’s Wikipedia entry describes him as “a harm reductionist, activist, musician, poet, writer, anarchist, and psychedelic practitioner.” He spent years using large amounts of heroin and cocaine, then put that all behind him with the help of ibogaine, which prompted him to start helping others with underground ibogaine sessions, which got him arrested, which lead him to become a leader in providing innovative wellness services for people in harm reduction programs, which, which, which… And all that only skims the surface of describing Dimitri’s remarkable journey and ongoing evolution as a compassionate and innovative helper of those who struggle with drugs and life.Listen to this episode and let me know what you think. Our number is 1-833-779-2460. Our email is psychoactive@protozoa.com. Or tweet at me, @ethannadelmann. Learn more about your ad-choices at https://www.iheartpodcastnetwork.comSee omnystudio.com/listener for privacy information.

Dec 2, 2021 • 1h 5min
Maia Szalavitz on the Pioneers of Harm Reduction
Author Maia Szalavitz discusses the pioneers of harm reduction and their impact on drug policy and addiction treatment. Topics include evidence-based treatments for addiction, the Dutch cannabis decriminalization approach, and the role of harm reduction in traditional treatment perspectives. The chapter also explores the lasting impact of the Tuskegee syphilis experiment and highlights the pioneers of harm reduction and needle exchange programs.

Nov 25, 2021 • 42min
Ephemeral - Drugs
As a holiday bonus episode, here's an interview I did with the podcast Ephemeral. To listen to more Ephemeral go to https://www.ephemeral.show or subscribe to the Ephemeral podcast.Let me know what you think. Our number is 1-833-779-2460. Our email is psychoactive@protozoa.com. Or tweet at me, @ethannadelmann. Learn more about your ad-choices at https://www.iheartpodcastnetwork.comSee omnystudio.com/listener for privacy information.

Nov 18, 2021 • 55min
Kate Nicholson on the Health & Human Rights of People in Pain
Fifty million Americans suffer from chronic pain. Most of us know what happened when pharmaceutical opioids were over-marketed and overprescribed in the United States but few people appreciate how far the pendulum has now swung in the opposite direction, with many doctors now refusing to prescribe opioids even to patients who have clearly benefited from them. Kate Nicholson served as a civil rights attorney in the U.S. Department of Justice for 18 years, during which time she developed intractable pain that left her unable to sit or stand and barely able to walk for nearly two decades. She recently started an organization, the National Pain Advocacy Center (NPAC), to advance the health and human rights of people in pain. This is an issue I’m passionate about, which is why I recently joined NPAC’s advisory board.I'll talk to Kate today about her own experience with this topic, the various ways states and doctors have restricted the prescribing of opioids, and what makes this a particularly American problem.Listen to this episode and let me know what you think. Our number is 1-833-779-2460. Our email is psychoactive@protozoa.com. Or tweet at me, @ethannadelmann. Learn more about your ad-choices at https://www.iheartpodcastnetwork.comSee omnystudio.com/listener for privacy information.

Nov 11, 2021 • 47min
David Mansfield on the Taliban, Afghanistan & Drugs
Afghanistan has produced most of the world's opium and heroin since the 1990s. With the Taliban's recent return to power, I was eager to talk with the world's leading expert on this subject, David Mansfield. I wanted to know why Afghanistan has occupied this role for so long, and how the Taliban’s involvement in illicit production and trade has changed over the years. Why is it we never hear about the sorts of narco-lords who became infamous in Mexico, Colombia and Burma? Could a different US anti-drug policy have prevented the Taliban takeover? How do Pakistan, Iran, China and Russia deal with Afghanistan on this issue?David addressed these questions and many more, including what we can expect from the Taliban now that they're back in power.Listen to this episode and let me know what you think. Our number is 1-833-779-2460. Our email is psychoactive@protozoa.com. Or tweet at me, @ethannadelmann. Learn more about your ad-choices at https://www.iheartpodcastnetwork.comSee omnystudio.com/listener for privacy information.

Nov 4, 2021 • 38min
Patt Denning on Doing Harm Reduction Therapy
Few people can explain harm reduction therapy better than Patt Denning. She’s a clinical psychologist who has played a pioneering role in developing the field, teaching and training thousands of health professionals. I talked with Patt about her own evolution in embracing harm reduction and how she teaches those who had been committed to 12-step and abstinence-only approaches. I asked her how she deals with people who have lost control of their drug use – and why a therapeutic session sometimes works better if the client has taken drugs just before the session.Listen to this episode and let me know what you think. Our number is 1-833-779-2460. Our email is psychoactive@protozoa.com. Or tweet at me, @ethannadelmann. Learn more about your ad-choices at https://www.iheartpodcastnetwork.comSee omnystudio.com/listener for privacy information.

Oct 28, 2021 • 54min
Carl Hart on Studying Drugs, Using Drugs & Staying Safe
Carl Hart is one of the bravest academics I know. His specialty is neuropsychopharmacology. He's the Ziff Professor of Psychology at Columbia University. He's published hundreds of scientific articles on psychoactive drugs, including many which challenge conventional thinking. And he wrote a book earlier this year in which he discussed his experience using heroin while serving as chairman of the Psychology Department. We talked about that, of course, but I also wanted his perspective on all sorts of other drugs, including MDMA, psychedelics and the growing variety of synthetic substances.Listen to this episode and let me know what you think. Our number is 1-833-779-2460. Our email is psychoactive@protozoa.com. Or tweet at me, @ethannadelmann. Learn more about your ad-choices at https://www.iheartpodcastnetwork.comSee omnystudio.com/listener for privacy information.