

Brain Inspired
Paul Middlebrooks
Neuroscience and artificial intelligence work better together. Brain inspired is a celebration and exploration of the ideas driving our progress to understand intelligence. I interview experts about their work at the interface of neuroscience, artificial intelligence, cognitive science, philosophy, psychology, and more: the symbiosis of these overlapping fields, how they inform each other, where they differ, what the past brought us, and what the future brings. Topics include computational neuroscience, supervised machine learning, unsupervised learning, reinforcement learning, deep learning, convolutional and recurrent neural networks, decision-making science, AI agents, backpropagation, credit assignment, neuroengineering, neuromorphics, emergence, philosophy of mind, consciousness, general AI, spiking neural networks, data science, and a lot more. The podcast is not produced for a general audience. Instead, it aims to educate, challenge, inspire, and hopefully entertain those interested in learning more about neuroscience and AI.
Episodes
Mentioned books
May 27, 2024 • 1h 28min
BI 188 Jolande Fooken: Coordinating Action and Perception
Jolande Fooken, a post-postdoctoral researcher, discusses hand-eye coordination and naturalistic tasks. Topics include various eye movements, levels of expertise, Yarbus' work, experimental paradigms for the brain, evolving views about the brain, and the intersection of coordination, robots, and AI.

Apr 20, 2024 • 1h 4min
BI 187: COSYNE 2024 Neuro-AI Panel
Neuroscientists and AI experts discuss the relationship between neuroscience and AI at the COSYNE conference. They explore historical influences, evolving research approaches, and the need for interdisciplinary collaboration for progress. Topics include the shift in priorities from neuroscience to AI, the intersection of neuroscience and AI, and predictions for the future of neuro-AI in 2044.
19 snips
Mar 25, 2024 • 1h 44min
BI 186 Mazviita Chirimuuta: The Brain Abstracted
Philosopher Mazviita Chirimuuta discusses simplification in neuroscience, highlighting the use of models, math, and analogies to understand the complex brain. She explores the intersection of neuroscience and philosophy, delves into simplification strategies in science, and emphasizes the interplay of technology and scientific understanding. The discussion touches on the challenges of interpreting scientific results, the limitations of reductionism, and the importance of maintaining a critical mindset in scientific pursuits.
Mar 6, 2024 • 1h 45min
BI 185 Eric Yttri: Orchestrating Behavior
Support the show to get full episodes, full archive, and join the Discord community.
As some of you know, I recently got back into the research world, and in particular I work in Eric Yttris' lab at Carnegie Mellon University.
Eric's lab studies the relationship between various kinds of behaviors and the neural activity in a few areas known to be involved in enacting and shaping those behaviors, namely the motor cortex and basal ganglia. And study that, he uses tools like optogentics, neuronal recordings, and stimulations, while mice perform certain tasks, or, in my case, while they freely behave wandering around an enclosed space.
We talk about how Eric got here, how and why the motor cortex and basal ganglia are still mysteries despite lots of theories and experimental work, Eric's work on trying to solve those mysteries using both trained tasks and more naturalistic behavior. We talk about the valid question, "What is a behavior?", and lots more.
Yttri Lab
Twitter: @YttriLab
Related papers
Opponent and bidirectional control of movement velocity in the basal ganglia.
B-SOiD, an open-source unsupervised algorithm for identification and fast prediction of behaviors.
0:00 - Intro
2:36 - Eric's background
14:47 - Different animal models
17:59 - ANNs as models for animal brains
24:34 - Main question
25:43 - How circuits produce appropriate behaviors
26:10 - Cerebellum
27:49 - What do motor cortex and basal ganglia do?
49:12 - Neuroethology
1:06:09 - What is a behavior?
1:11:18 - Categorize behavior (B-SOiD)
1:22:01 - Real behavior vs. ANNs
1:33:09 - Best era in neuroscience
14 snips
Feb 20, 2024 • 1h 31min
BI 184 Peter Stratton: Synthesize Neural Principles
The podcast discusses synthesizing neural principles for better AI, focusing on a 'sideways-in' approach for computational brains. It explores integrating diverse brain operations, the challenges in achieving general-purpose AI, advancements in robotics inspired by biological principles, and the complexities of spiking neural networks for artificial general intelligence.
4 snips
Feb 6, 2024 • 1h 29min
BI 183 Dan Goodman: Neural Reckoning
Dan Goodman, co-founder of Neuromatch and creator of the Brian spiking neural network simulator, discusses the importance of spikes in intelligent systems and the curious choice of modern neural networks to disregard spiking. They delve into the intricacies of spiking neural networks, the transition from math to neuroscience, the creation of complex tasks for neural networks, and the challenges in training them. They also explore the impact of advanced technology on human intelligence.
27 snips
Jan 19, 2024 • 1h 26min
BI 182: John Krakauer Returns… Again
Neuroscientist and author John Krakauer returns to discuss brain reorganization, plasticity, motor problems after strokes, and artificial general intelligence. They explore the misconception of brain reorganization, the challenges in studying behavioral outcomes after a stroke, and the need to critically analyze scientific papers and challenge established ideas.
43 snips
Dec 25, 2023 • 1h 28min
BI 181 Max Bennett: A Brief History of Intelligence
Max Bennett, an entrepreneur and author, discusses the breakthroughs in brain evolution and their impact on intelligence. Topics covered include the role of the neocortex in simulating and imagining, counterfactual learning, episodic memory, and the challenges of building human-like AI systems.
Dec 11, 2023 • 1h 29min
BI 180 Panel Discussion: Long-term Memory Encoding and Connectome Decoding
Panel discussion on using neuroscience technologies to decode memory from connectomes, featuring a group of experts including Kenneth Hayworth. Topics include advancements in connectomics, decoding memory and connectomes, analyzing connectome complexity, the role of molecules, deep learning parallelism, studying connectome data with cultured neurons, understanding neuronal interactions, and the rules of connectome interpretation.
Nov 27, 2023 • 1h 39min
BI 179 Laura Gradowski: Include the Fringe with Pluralism
Laura Gradowski, a philosopher of science at the University of Pittsburgh, discusses the importance of scientific pluralism and the inclusion of fringe theories in science. She cites historical examples, including the Garcia effect, that challenge mainstream theories and highlight the need for tolerance and diversity in scientific research. The podcast explores various topics such as the transition of fringe ideas to mainstream acceptance, the validation of traditional ecological knowledge, and the role of constraints in generating movement and thoughts. It also delves into the concept of the 'no end principle' and the continuous exploration of new ideas in science.


