This Week in Virology

Connor joins the TWiV team to discuss bats as hosts for major mammalian paramyxoviruses. Links for this episode: NIH response to Osterholm letter (pdf) Who's afraid of the big, bad bioterrorist? Bats host major mammalian paramyxoviruses (Nature Comm) TWiV on Facebook Letters read on TWiV 183 Weekly Science Picks Connor - Microbiology Twitter journal clubAlan - Where the Wild Types Are (YouTube)Rich - May 14th: Smallpox vaccination dayDickson - Searching for pore-fection (Science)Vincent - RRResearch Listener Pick of the Week Stephen - Every Major's Terrible (xkcd)

Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Michael J. Imperiale Michael joins the TWiV crew to discuss the recently published influenza H5N1 transmission paper and how it was viewed by the NSABB. Links for this episode: About the NSABB The Kawaoka paper (Nature) Mutant flu paper published (Ed Yong) Osterholm letter (pdf) US policy for dual research of concern (pdf) TWiV on Facebook Letters read on TWiV 182 Weekly Science Picks Alan - 18th century shipping mappedRich - Brave New World by Aldous HuxleyVincent - Air France 447 (Telegraph) Listener Pick of the Week Josh - Vaccines course by Dr. Paul Offit

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Vincent, Rich, and Kathy discuss Cotia virus, a new poxvirus, Orf virus infections associated with handling goats and lamb, and the innate immune response to prions. Links for this episode: Cotia virus (J Virol) Human Orf virus exposures (MMWR) IRF3 protects agains prion infection (J Virol) A mad cow in America (virology blog) Human orf (pdf) Space shuttle flies outside my window (YouTube) TWiV on Facebook Letters read on TWiV 181 Weekly Science Picks Kathy - Astronomy Picture of the Day (especially this and this)Rich - Tom Lehrer Element Song (YouTube)Vincent - Albert B. Sabin Archives Listener Pick of the Week Mark - Netter's Infectious Diseases by Elaine C. Jong and Dennis L. StevensRichard - Germs, Genes & Civilization by David P. Clark

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich review association of an interferon-induced protein with severe influenza, and stabilization of HCV RNA by a microRNA. Links for this episode: IFITM3 and severe influenza (Nature) Genetics of flu susceptibiligy (EurekAlert!) Stabilization of HCV RNA by Ago2-miR-122 (PNAS) Clinical trial of anti-mIR-122 TWiV on Facebook Letters read on TWiV 180 Weekly Science Picks Alan - Micro Empire (Vimeo)Rich - Census of marine lifeVincent - Pinterest Listener Pick of the Week Mark - The Secret Life of Plankton (YouTube)

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Gertrud Radu Gertrud joins the TWiVoners to review how dengue virus infection of mosquitoes alters blood feeding behavior, and gene therapy as practiced by parasitoid wasps. Links for this episode: Renato Dulbecco, 1914-2012 (virology blog) William Jarrett, 83 (thanks, Lynn Enquist) Dengue virus infection of mosquitoes alters their behavior (PLoS Path) Does dengue make mosquitoes thirstier for blood? (NY Times) Polydnaviruses of braconid wasps (Science) Making nice with viruses (Science) Viral and wasp genes involved in symbiotic replication (J Virol) Amazing parasitic wasp images The Far Side cartoon on mosquitoes (gif) TWiV on Facebook Letters read on TWiV 179 Weekly Science Picks Gertrud - Bat on a plane! (MMWR)Alan - The Rings of Earth (YouTube)Rich - Giant Magellan telescopeVincent - Hepatitis C new drug pipeline Listener Pick of the Week Ricardo - Evolution: The Natural History of Animal SkeletonsPeter - Self-assembly line (YouTube)

The TWiValians meet up with Tyler Sharp for a discussion on the Epidemic Intelligence Service and controlling dengue. Links for this episode: 2010 dengue epidemic in Puerto Rico Marshall Islands dengue outbreak (one and two) Photo of Tyler by Loren Rodgers TWiV shout-out by NPR and CIDRAP NSABB reverses decision on H5N1 publication TWiV on Facebook Letters read on TWiV 178 Weekly Science Picks Tyler - Co-infection with dengue and Leptospira (Emerging Inf Dis)Alan - The Winged Scourge (YouTube)Rich - Deepsea ChallengeVincent - Why did a US advisory board reverse its stance? (Ed Yong) Listener Pick of the Week Sasha - Microfluidic FutureAdam - The ConversationJim - ENIAC Programmers Project

A discussion of avian influenza H5N1 transmission experiments in ferrets and novel bunyaviruses at the 2012 Spring Conference of the Society for General Microbiology in Dublin, Ireland. Links for this episode: Restricted data on H5N1 transmission (Science) Novel bunyavirus in China (NEJM and TWiV 127) Ten things about Schmallenberg virus (Microbiology Bytes) NSABB reverses decision on H5N1 papers (virology blog) TWiV on Facebook Letters read on TWiV 177 Weekly Science Picks Connor - Wellcome Trust Science Writing Prize 2012Vincent - Thoughts on academic scientists giving media interviews

Vincent, Alan, and Rich answer listener email about MS, CFS, EBV, B cells, virii, influenza B, scientific papers, and more. Links for this episode: More than one way to skin a virus (comments) Aerobie aeropress Papers software Vaccinia movies (one and two) Lloyd Kozloff dies BSL4 facilities TWiV on Facebook Letters read on TWiV 176 Weekly Science Picks Rich - Alan Alda's Flame Challenge (NY Times article, Science editorial)Alan - ChronoZoomVincent - Academic Publishing is Broken by Michael P. Taylor Listener Pick of the Week Joel - Fighting a dengue outbreak by Tyler M. Sharp (parts one and two)Sven-Urban - Fooled by Randomness and The Black Swan by Nassim Nicholas Taleb

Vincent, Alan, and Matt discuss herpes simplex encephalitis in children with innate immune deficiency, and the local response to microneedle-based influenza skin immunization. Links for this episode: Herpes encephalitis in children with TRIF deficiency (J Clin Inv) Toll-like receptor and cytosolic pattern recognition receptors Skin responses to influenza microneedle vaccine (mBio) Microneedles Fluzone intradermal influenza vaccine QDot nanocrystal technology TWiV on Facebook Letters read on TWiV 175 Weekly Science Picks Matt - Phage and the Origins of Molecular BiologyAlan - Digital Imagine InstituteVincent - iPad apps Goodreader and Notability Listener Pick of the Week Jane -Smoking Ears and Screaming Teeth by Trevor Norton

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich consider whether pet dogs might transmit human noroviruses, and an RNA virus microRNA that might be involved in oncogenesis. Links for this episode: Do pet dogs transmit human norovirus? (J Clin Virol) RNA virus miRNA that mimics oncomiR (PNAS) MicroRNA expression by an RNA virus (PNAS) Lab safety stickers jpg (thanks, Jon!) Amateur virologists (Zimmer, NY Times) Genome at home (Wired) Barbergators sing national anthem (YouTube) TWiV on Facebook Letters read on TWiV 174 Weekly Science Picks Rich - NOAA Buoy DataAlan - Autism's False Prophets by Paul OffitVincent - Media Mining Listener Pick of the Week Mark - How the West fueled the AIDS epidemicHenry - RegenesisRick - Biopunk: DIY scientists hack the software of life by Marcus Wohlsen