Dr. Seyfried's research suggests that cancer is a disruption of mitochondrial oxidative phosphorylation, not a genetic disease. Transitioning cells to ketones, targeting glucose and glutamine, and using hyperbaric oxygen therapy are potential strategies to combat cancer. The podcast also explores the use of the calorie-restricted ketogenic diet as a therapeutic approach, the potential use of D beta hydroxybutyrate as a ketone therapy, and the role of diet and nutrition in cancer prevention.

The Art of Medicine: A Soul-Stirring Chat with Sidney Baker, MD

Science has demonstrated for over a century that fat simply isn’t the macronutrient villain it’s been made out to be. Join me and Dr. Mark Hyman as we spend some time discussing his new NYT best-selling book Eat Fat, Get Thin. We drill down into the research that has been published over the years demonstrating the largely beneficial aspects of most fatty acids.

The oral-systemic disease connection has long been established (recall older recommendations for prophylactic antibiotics before dental work in individuals with endocarditis or joint implants), but with the emerging data on the oral microbiome, new attention is being paid to oral health and the prevention of diseases ranging from cardiovascular to autoimmune and more. A transient bacteremia is the normal course after brushing, but when there is a breakdown in oral health and alterations to the oral microbiome, this transient bacteremia leads to chronic, systemic inflammation, contributing to the course of systemic disease. There is much we can do to support our patients in correcting this inflammation, not the least of which includes a healthy, sugar-free diet; regular cleanings and appropriate brushing techniques. Ideally, the dentist is a part of the functional medicine team. Disordered sleep breathing is a wide-spread, underappreciated problem in children and adults. Once thought to be primarily stress or trauma related, bruxism is now understood to be evidence of disordered breathing (see reference link below). Additionally, a scalloped or fissured tongue (macroglossia) also contribute to disordered sleep breathing.

David S. Ludwig, MD, PhD, is a practicing endocrinologist and researcher at Boston Children’s Hospital, Professor of Pediatrics at Harvard Medical School and Professor of Nutrition at Harvard School of Public Health. He is Founding Director of the Optimal Weight for Life (OWL) program at Boston Children’s Hospital, one of the oldest and largest family based weight management programs. He also directs the New Balance Foundation Obesity Prevention Center. Described as an “obesity warrior” by Time Magazine, he has been featured in the New York Times, Boston Globe and USA Today and on NPR, ABC, NBC, CBS, CNN and other networks. His new book ALWAYS HUNGRY? published on January 5 is a New York Times bestseller drdavidludwig.com/ www.facebook.com/davidludwigmd/

As a clinician measuring urine, serum and salivary hormone levels in my patients routinely, I’ve always got questions around which testing method is the best. Thus, I was excited to chat with Mark Newman and pick his brain on all things hormone testing. As he says, “I’m an inch wide and a mile deep. I’ve spent pretty much my whole career in measuring reproductive and adrenal hormones.” It’s true. As you’ll hear, Mark is a font of knowledge in this arena. In this interview, Mark covers the various specimen type and their respective utility and limitations, we then dive into a discussion around the unique characteristics of the DUTCH test….In brief, DUTCH is an easy 4 specimen urine test, collected over the course of a day, covering the bases of sex and adrenal hormones, plus metabolites (including 2-Methoxyestrone) and melatonin. It’s reflective of 24-hour output, but diurnal variation is captured as well-- thus great for cortisol.

JEFFREY S. BLAND, PhD, FACN, CNS, is an internationally recognized leader in the nutritional medicine field. He co-founded of the Institute for Functional Medicine in 1991 and is known to many as the “father of functional medicine.” Over the past 35 years, Dr. Bland has traveled more than six million miles teaching more than 100,000 health care practitioners in the USA, Canada, and 50 other countries about functional medicine.

Imagine: You’re a busy FxMed clinician, working overtime treating, educating and supporting your patients as they transition to a new state of health. It’s exciting, and you’re inspired to be practicing medicine in a way you never thought possible. But (to put it mildly) you’re struggling with time management: FxMed is a lot of work! And then into your life comes an individual just as passionate as you are about functional medicine, who happens to be a trained, certified Functional Medicine Coach! They’ve learned the “ins and outs” of Positive Psychology, so they understand the change process and can guide your patients supportively and effectively. They’re also familiar with the Functional Medicine model, having been taught by many IFM faculty, so they can assist you with educating and “translating” the FxMed processes. Would this individual be a Godsend to your practice? YES! Learn about functional medicine’s newest team member in this podcast with the Founder and CEO of the Functional Medicine Coaching Academy, Dr. Sandy Scheinbaum. This podcast is perfect for clinicians, folks interested in a FxMed Coaching career, and anyone interested in the process of FxMed.

According to Dr. Bob Hedaya, it’s malpractice NOT to use functional medicine when practicing psychiatry. ALL of the nodes on the Functional Medicine Matrix [gastrointestinal, endocrine, immune, toxicity, nutritional status and especially psychological, social and spiritual] influence mental health, mental function and brain function. The bottom line is, a good functional approach yields better health, less medicine. In this case-focused inspiring podcast, hear about Dr. Hedaya’s years of clinical experience in using functional medicine to address tough psychiatric conditions.

From Cell to Soul: A Functional Approach to Women’s Hormone Management with Sara Gottfried, MD. Dr. Sara Gottfried has elegantly distilled her years of clinical experience and thousands of patient contacts into a user-friendly body of knowledge for physician and layperson alike. She’s truly a functional/systems medicine pioneer, combining the best of scientific data with the art (and heart) of medicine. An expert in the area of women's hormones, Dr. Gottfried candidly shares her own personal experience with hormone imbalances. Sara was pivotal on my own journey toward better self-care, as you’ll hear in this podcast.