Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics

Dr. Kara Fitzgerald
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Dec 16, 2025 • 1h 20min

The Oral Microbiome: The Hidden Biomarker Driving Aging, Fertility & Systemic Inflammation

Functional dentistry is emerging as a powerful missing link in systems-based care. In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald sits down with Staci Whitman, DMD, IFMCP, a leading voice in functional pediatric dentistry and co-founder of the upcoming Institute for Functional Dentistry. Together, they explore how the oral microbiome, airway health, saliva, hormones, nutrition, and stress physiology shape systemic inflammation, chronic disease risk, and long-term health outcomes. You’ll learn how to recognize oral contributors to gut issues, autoimmunity, cardiometabolic disease, cognitive decline, sleep disorders, and more—plus practical tools you can use right away in a medical setting, including a simple five-question airway and breathing screener. If you’re looking to expand your longevity and whole-body health framework, this conversation offers clear, actionable insights you won’t want to miss. Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/ GUEST DETAILS Dr. Staci Whitman is a board-certified pediatric and functional dentist and co-founder of the Institute for Functional Dentistry (IFD). She integrates the oral microbiome, airway and sleep health, nutrition, hormones, and early childhood development into modern dental care. She also founded Bloom Kids Dentistry and has an upcoming book on the oral microbiome. Website: http://doctorstaci.com THANKS TO OUR SPONSORS DIAMOND DUTCH: https://dutchtest.com/for-providers Biotics Research: https://bit.ly/2IHK6Xd GOLD TimeLine Nutrition: https://tinyurl.com/bdzx2xms Vibrant Wellness: https://www.vibrant-wellness.com/ EXCLUSIVE OFFERS FROM OUR SPONSORS OneSkin: Get 15% off OneSkin with the code DRKARA at http://oneskin.co/DRKARA Find out why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy. http://mitoq.com/drkara *CONNECT with DrKF* Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/ Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw
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Dec 2, 2025 • 1h 6min

The Hidden Immune Signal Accelerating Aging & the Beta-Glucan That Fixes It

Beta-glucans might be one of the most overlooked levers in immune resilience, and that has major implications for longevity. Talking with my long-time friends and colleagues Drs. Bob Rountree and Chris D’Adamo reminded me just how powerful this molecule truly is. The clinical reach here is stunning, from immune aging and cancer support to vaccine response, gut–brain effects, and overall resilience. What struck me most is how beta-glucans help the innate immune system respond more effectively over time, from overtraining and chronic infections to vaccine responsiveness. Clinicians really need this on their radar. I think you’re going to find this conversation eye-opening. ~DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Bob Rountree, MD, is a leading figure in integrative and functional medicine with more than 40 years of clinical experience. Medical Director of Boulder Wellcare and long-time IFM faculty, he is widely published and a respected educator in personalized medicine, botanical therapies, and immune health. Chris D’Adamo, PhD, is a research scientist and epidemiologist focused on how nutrition, lifestyle, and environmental factors influence health. An Assistant Professor at the University of Maryland School of Medicine, he has led numerous clinical studies, published widely, and is a trusted advisor and educator in integrative and lifestyle medicine. THANKS TO OUR SPONSOR BetterWay Health (Consumers) BWHLabs (Practitioners) WEBSITE: http://bwhlabs.com/kara EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS Book a practitioner call and receive a complimentary bottle of beta-glucan to try personally or with a patient at http://bwhlabs.com/kara CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/ Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw
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Nov 17, 2025 • 1h 4min

From Hot Flashes to Healthspan: The FxMed Guide to Hormones & Longevity

In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald sits down with hormone and women’s health expert Dr. Carrie Jones to explore the powerful connection between mitochondrial health and women’s hormones. Together, they unpack how mitochondrial function influences hormone balance, metabolism, energy, mood, and resilience, especially during perimenopause and menopause. Dr. Jones shares practical, evidence-based strategies to support mitochondrial health for optimal hormonal balance, improved sleep, and emotional well-being. Listeners will gain actionable insights into functional medicine approaches to women’s hormone health, including how mitochondrial vitality can help ease hormonal transitions and enhance longevity. Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Dr. Carrie Jones, ND, FABNE, MPH, MSCP is an internationally recognized expert in women’s health and hormones. Known as the “Queen of Hormones,” she’s a naturopathic physician, educator, and Chief Medical Officer at NuEthix Formulations. With over 20 years in the field, Dr. Jones has shaped hormone education through her work with major functional labs and her hit podcast, Hello Hormones. Email: drjones@drcarriejones.com Website: https://www.drcarriejones.com/ THANKS TO OUR SPONSORS DIAMOND DUTCH: https://dutchtest.com/for-providers Biotics Research: https://bit.ly/2IHK6Xd GOLD TimeLine Nutrition: https://tinyurl.com/bdzx2xms Vibrant Wellness: https://www.vibrant-wellness.com/ EXCLUSIVE OFFERS FROM OUR SPONSORS OneSkin: Get 15% off OneSkin with the code DRKARA at http://oneskin.co/DRKARA Find out why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy. http://mitoq.com/drkara *CONNECT with DrKF* Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/ Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw
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Nov 4, 2025 • 36min

Guide to Building a Sustainable Concierge Longevity Practice

Dr. Brooke Stubbs, a double board-certified physician and founder of Rooted Femme, shares her journey from hospitalist medicine to a concierge model focused on women's health. She discusses the transition to preventive care, emphasizing personalized lifestyle changes for fertility and overall well-being. Brooke also dives into the logistics of building a concierge practice, including pricing strategies and the benefits of opting out of insurance. Her insights on functional lab integration and community engagement through wellness retreats offer valuable guidance for modern practitioners.
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Oct 20, 2025 • 37min

Reversing Aging: Screening, Wearables & What To Do Now

Dr. Kara Fitzgerald talks with Sergey Young, founder of the Longevity Vision Fund and XPRIZE board member, about the future of aging medicine. Hear how AI, wearables, new diagnostics, and early screening are making longevity solutions more practical, affordable, and clinically relevant for functional medicine practitioners. Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Sergey Young is a longevity investor, author, and visionary committed to extending healthy lifespans for one billion people. He co-founded the BOLD Longevity Growth Fund, wrote the bestseller The Science and Technology of Growing Young, and serves on the boards of XPRIZE and AFAR. Website: https://sergeyyoung.com/ Follow Sergey: @sergeyyoung200 THANKS TO OUR SPONSORS DIAMOND DUTCH: https://dutchtest.com/for-providers GOLD Vibrant Wellness: https://www.vibrant-wellness.com/ TimeLine Nutrition: https://tinyurl.com/bdzx2xms EXCLUSIVE OFFERS FROM OUR SPONSORS Find out why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy. http://mitoq.com/drkara OneSkin: Get 15% off OneSkin with the code DRKARA at http://oneskin.co/DRKARA CONNECT with DrKF - Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/ Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw
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Oct 7, 2025 • 47min

Aging & Hair Loss Explained: OS-01’s Science-Backed Approach

Hair loss is more than cosmetic. In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald explores new research on the OS-01 peptide and its role in targeting senescent cells. Learn how peptide therapy compares to minoxidil, and how hormones, thyroid health, stress, UV exposure, and the scalp microbiome all play a role in thinning hair. Carolina Reis Oliveira, PhD, co-founder of OneSkin, shares insights on how polyphenols, prebiotics, and integrative strategies can support healthier growth. Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Carolina Reis Oliveira, PhD - OneSkin Co-Founder & CEO Carolina Reis Oliveira, PhD, is the CEO and co-founder of OneSkin and an advocate for healthy aging. With a doctorate in immunology, she moved from Brazil to Silicon Valley to pursue her vision of using science to prevent age-related diseases. At OneSkin, she leads pioneering research on aging biology, including the development of the proprietary OS-01 peptide, the first scientifically proven to reverse skin’s biological age. THANKS TO OUR SPONSOR OneSkin: http://oneskin.co/DRKARA EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS Interested in reclaiming your roots and addressing hair thinning? Visit https://oneskin.co/DRKARA for 15% off your purchase of OneSkin’s OS-01 HAIR peptide scalp serum. CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw
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Sep 25, 2025 • 56min

The Bile Acid Imbalance Accelerating Aging: How to Detect ​& Fix It

Dr. Tom Fabian, a translational scientist and microbiome research expert, sheds light on bile acid imbalances and their role in gut health. He discusses how specific types of inflammation and microbial patterns can guide interventions to improve patient outcomes. Notably, Tom connects low butyrate levels to inflammatory bowel disease and reveals the surprising ways some fibers might exacerbate gut irritation. He emphasizes using StoolOMX and GI-MAP tests for precision medicine in complex cases, making science practical for clinicians.
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Sep 3, 2025 • 55min

Why Functional Medicine Is the Future of Longevity

Can functional medicine unlock the secrets to healthy aging? In this special preview of the Functional Medicine is Longevity Medicine™ Masterclass happening on September 17- September 19, 2025, Dr. Kara Fitzgerald sits down with three leading voices in medicine and research: - Dr. Bob Rountree: functional medicine pioneer in integrative approaches to health - Dr. Dale Bredesen: internationally recognized expert on Alzheimer’s prevention and reversal - Dr. Charles Serhan: Harvard researcher on inflammation resolution and aging biology Together, they explore how functional medicine reframes longevity by addressing root causes, supporting cognitive health, and resolving chronic inflammation. Whether you’re a clinician, health professional, or simply passionate about living longer and healthier, this conversation offers a glimpse into the science and practical applications that are transforming longevity medicine. WATCH NOW TO LEARN: - Why functional medicine is central to extending healthspan - The latest insights on Alzheimer’s prevention and brain health - How inflammation resolution impacts aging and chronic disease - What to expect in the full Functional Medicine is Longevity Medicine™ Masterclass Learn more & register for the Masterclass here: www.functionalmedicineislongevitymedicine.com THANKS TO OUR SPONSORS DIAMOND DUTCH: https://dutchtest.com/for-providers Biotics Research: https://www.bioticsresearch.com/ GOLD TimeLine Nutrition: https://tinyurl.com/bdzx2xms Vibrant Wellness: https://www.vibrant-wellness.com/ EXCLUSIVE OFFERS FROM OUR SPONSORS OneSkin: Get 15% off OneSkin with the code DRKARA at http://oneskin.co/DRKARA Discover why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy. http://mitoq.com/drkara
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Aug 17, 2025 • 1h 22min

Why Centenarians Are Defying Science: Secrets to Living 100+

It was a pleasure to sit down with Dr. Nir Barzilai for a conversation that turned out to be both lively and thought-provoking. His decades of research on centenarians, biological age, and the hallmarks of aging have shaped how we think about longevity—and what’s possible when we start targeting aging itself, not just individual diseases. We get into the science behind why some people live 20–30 years longer and healthier, and what it means to measure the biological age of individual organs. But we also hit a few sparks—especially when it comes to nutraceuticals and the role of metformin in prevention. I don’t agree with everything you’ll hear, and I followed up with Dr. Barzilai afterward to unpack some of the more provocative claims. We may just need a second round for this one... stay tuned. Check out the show notes at www.drkarafitzgerald.com/fxmed-podcast/ for all the relevant links and resources. ~DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Nir Barzilai M.D. Director of the Einstein Institute for Aging Research Professor of Medicine and Genetics President of the Academy for Health & Lifespan Research Website: https://einsteinmed.edu/faculty/484/nir-barzilai Email: nir.barzilai@einsteinmed.edu Dr. Nir Barzilai is a pioneer in aging science, known for his work on centenarians, the biology of aging, and the TAME trial. He is Director of the Institute for Aging Research at Albert Einstein College of Medicine and author of Age Later and has published over 330 papers. THANKS TO OUR SPONSORS DIAMOND DUTCH: https://dutchtest.com/for-providers Biotics Research: https://www.bioticsresearch.com/ GOLD Vibrant Wellness: https://www.vibrant-wellness.com/ OneSkin: http://oneskin.co/DRKARA EXCLUSIVE OFFERS FROM OUR SPONSORS Find out why MitoQ’s mitochondria-targeting is a critical step for your healthspan and longevity strategy. http://mitoq.com/drkara OneSkin: Get 15% off OneSkin with the code DRKARA at oneskin.co/DRKARA CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Practitioner Training Program: https://www.drkarafitzgerald.com/trainingyyi/ Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw
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Aug 5, 2025 • 53min

The Science-Backed Bitter Compound That Mimics GLP-1 (No Injections Needed!)

I’ve been watching the science behind Calocurb evolve over the last year, and I have to say—this is one of the most exciting clinical tools I’ve seen emerge in the metabolic space in quite some time. A hops-derived compound that stimulates endogenous GLP-1, CCK, and PYY—without a prescription or injection? That’s a big deal, especially for patients struggling with appetite regulation, weight plateaus, or the aftermath of GLP-1 discontinuation. In this episode, I sit down with Sarah Kennedy, founder of New Zealand-based Calocurb, to talk about the years of government-funded research that led to this discovery, the remarkable clinical outcomes they’ve seen so far, and how I’ve personally used it in my practice with excellent results. If you’re looking for science-backed, natural strategies to support appetite control, fasting, or GLP-1 transitions—this one’s worth a listen. ~DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Sarah Kennedy, Founder and CEO of Calocurb Ltd. Email: sarah.kennedy@calocurb.com LinkedIn: https://www.linkedin.com/in/sarah-kennedy-0a840b13/ Sarah Kennedy, BVSc, is a veterinarian and health industry leader with 20+ years in nutrition science and innovation. Now CEO of Calocurb, she brings a unique perspective on natural GLP-1 activation—bridging plant-based research, gut physiology, and clinical application. THANKS TO OUR SPONSOR: Calocurb EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS Manage cravings and feel full faster with Calocurb, a 100% natural capsule that supports healthy weight management. Visit http://calocurb.com/drkara10 and use code DRKARA10 at checkout. CONNECT with DrKF Join Dr. Kara Fitzgerald and leading experts *LIVE on Sept 17–19, 2025* for a free virtual Masterclass on redefining healthcare & longevity through the lens of science-backed, systems-based approach. Register now: https://www.functionalmedicineislongevitymedicine.com/ Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

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